(Q37134357)

English

Bioluminescence resonance energy transfer studies reveal constitutive dimerization of the human lutropin receptor and a lack of correlation between receptor activation and the propensity for dimerization

scientific article published on 15 January 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Bioluminescence resonance energy transfer studies reveal constitutive dimerization of the human lutropin receptor and a lack of correlation between receptor activation and the propensity for dimerization (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

bioluminescence

0 references

author name string

Rongbin Guan

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Xiuyan Feng

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Xueqing Wu

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Meilin Zhang

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Xuesen Zhang

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Terence E Hébert

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Deborah L Segaloff

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

15 January 2009

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

284

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

7483-7494

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

G protein-coupled receptor dimers: functional consequences, disease states and drug targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

An intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.

1 reference

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Allosteric modulation of heterodimeric G-protein-coupled receptors.

1 reference

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A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization

1 reference

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14 September 2017

Allosteric properties of G protein-coupled receptor oligomers

1 reference

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Follice-stimulating hormone receptor forms oligomers and shows evidence of carboxyl-terminal proteolytic processing

1 reference

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14 September 2017

G protein-coupled receptor dimerisation: molecular basis and relevance to function

1 reference

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14 September 2017

Potential Leydig cell mitogenic signals generated by the wild-type and constitutively active mutants of the lutropin/choriogonadotropin receptor (LHR).

1 reference

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14 September 2017

Calcium-sensing receptor dimerizes in the endoplasmic reticulum: biochemical and biophysical characterization of CASR mutants retained intracellularly.

1 reference

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Detecting and imaging protein-protein interactions during G protein-mediated signal transduction in vivo and in situ by using fluorescence-based techniques.

1 reference

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Functional and structural characterization of rhodopsin oligomers

1 reference

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14 September 2017

Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET).

1 reference

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14 September 2017

Cell-surface targeting of alpha2-adrenergic receptors -- inhibition by a transport deficient mutant through dimerization

1 reference

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14 September 2017

Methods to monitor the quaternary structure of G protein-coupled receptors

1 reference

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14 September 2017

The formation of a salt bridge between helices 3 and 6 is responsible for the constitutive activity and lack of hormone responsiveness of the naturally occurring L457R mutation of the human lutropin receptor

1 reference

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14 September 2017

Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation

1 reference

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14 September 2017

A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia

1 reference

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14 September 2017

Insight into mutation-induced activation of the luteinizing hormone receptor: molecular simulations predict the functional behavior of engineered mutants at M398.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

A molecular dissection of the glycoprotein hormone receptors.

1 reference

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14 September 2017

Roles of G-protein-coupled receptor dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Dimerization of G-protein-coupled receptors: roles in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Self-association and raft localization of functional luteinizing hormone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716

1 reference

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14 September 2017

G protein-coupled receptor allosterism and complexing

1 reference

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14 September 2017

The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Lutropin receptor function: insights from natural, engineered, and computer-simulated mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

1 reference

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14 September 2017

Constitutive and agonist-dependent homo-oligomerization of the thyrotropin-releasing hormone receptor. Detection in living cells using bioluminescence resonance energy transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Luteinizing hormone receptors are self-associated in slowly diffusing complexes during receptor desensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Heterodimerization of mu and delta opioid receptors: A role in opiate synergy

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14 September 2017

Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

1 reference

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14 September 2017

AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration

1 reference

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14 September 2017

Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity

1 reference

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14 September 2017

HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.

1 reference

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14 September 2017

The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway

1 reference

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14 September 2017

Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors.

1 reference

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14 September 2017

The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2

1 reference

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14 September 2017

Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function

1 reference

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14 September 2017

Serotonin 5-HT2C receptor homodimer biogenesis in the endoplasmic reticulum: real-time visualization with confocal fluorescence resonance energy transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

14 September 2017

The CXCR1 and CXCR2 receptors form constitutive homo- and heterodimers selectively and with equal apparent affinities

1 reference

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14 September 2017

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

1 reference

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14 September 2017

Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting

1 reference

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14 September 2017

Constitutive and agonist-dependent self-association of the cell surface human lutropin receptor

1 reference

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14 September 2017

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer

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29 September 2017

Constitutive activation of the LH receptor is associated with an alteration in the conformation of the ectodomain

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29 September 2017

Cis- and trans-activation of hormone receptors: the LH receptor

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29 September 2017

Two defective heterozygous luteinizing hormone receptors can rescue hormone action

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29 September 2017

Involvement of the amino terminus of the B(2) receptor in agonist-induced receptor dimerization.

1 reference

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29 September 2017

Constitutively-active human LH receptors are self-associated and located in rafts.

1 reference

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1 reference

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27 June 2018

An inactivating mutation of the luteinizing hormone receptor causes amenorrhea in a 46,XX female.

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27 June 2018

BRET analysis of GPCR oligomerization: newer does not mean better

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Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells.

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3 September 2018

Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers.

1 reference

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3 September 2018

Negative cooperativity of glutamate binding in the dimeric metabotropic glutamate receptor subtype 1.

1 reference

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3 September 2018

Intracellularly located misfolded glycoprotein hormone receptors associate with different chaperone proteins than their cognate wild-type receptors

1 reference

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3 September 2018

A constitutively active somatic mutation of the human lutropin receptor found in Leydig cell tumors activates the same families of G proteins as germ line mutations associated with Leydig cell hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658044

3 September 2018

Ligand-dependent inhibition of oligomerization at the human thyrotropin receptor

1 reference

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3 September 2018

Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells.

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3 September 2018

Brief report: testicular and ovarian resistance to luteinizing hormone caused by inactivating mutations of the luteinizing hormone-receptor gene.

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3 September 2018

Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors

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21 January 2018

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4 December 2018

Theoretical study on mutation-induced activation of the luteinizing hormone receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

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inferred from PubMed ID database lookup

Luteinizing hormone receptors are self-associated in the plasma membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of two distinct structural motifs that, when added to the C-terminal tail of the rat LH receptor, redirect the internalized hormone-receptor complex from a degradation to a recycling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model for constitutive lutropin receptor activation based on molecular simulation and engineered mutations in transmembrane helices 6 and 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane organization of luteinizing hormone receptors differs between actively signaling and desensitized receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporation of Radiolabeled Amino Acids into Protein Subunits of the Rat Leydig Cell Gonadotropin Receptor: Application to the Study of Receptor Structure and Turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of mechanistic proposals for the binding of agonists to cardiac muscarinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of ovarian gonadotropin receptor. Monomer and associated form of the receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor 5 is a disulfide-linked dimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfected cells express mostly the intracellular precursor of the lutropin/choriogonadotropin receptor but this precursor binds choriogonadotropin with high affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lutropin/choriogonadotropin receptor, a 2002 perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/19147490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M809150200

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

release_fvavgsbb6jbztoex5nadyyeg2q

1 reference

https://api.fatcat.wiki/v0/release/fvavgsbb6jbztoex5nadyyeg2q

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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