(Q37136752)

English

The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB

scientific article published on 12 January 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

apoptotic process

0 references

Francesca Demarchi

object named as

Francesca Demarchi

7

0 references

Claudio Brancolini

object named as

Claudio Brancolini

8

0 references

Roberta Maestro

object named as

Roberta Maestro

5

0 references

object named as

Paolo Bernardi

6

0 references

author name string

Alessandra Fontanini

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Carmela Foti

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Harish Potu

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Enrico Crivellato

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

12 January 2009

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

284

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

8369-8381

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Inhibitors of the Ubiquitin-Proteasome System and the cell death machinery: How many pathways are activated?

1 reference

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14 September 2017

Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities

1 reference

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Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

1 reference

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The roles of therapy-induced autophagy and necrosis in cancer treatment

1 reference

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

1 reference

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Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus

1 reference

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The proteasome: a worthwhile target for the treatment of solid tumours?

1 reference

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Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance

1 reference

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Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death

1 reference

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

1 reference

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Role of alterations in the apoptotic machinery in sensitivity of cancer cells to treatment

1 reference

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Cell death by necrosis: towards a molecular definition

1 reference

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14 September 2017

Role of the mitochondrial membrane permeability transition in cell death

1 reference

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Calpain is required for macroautophagy in mammalian cells

1 reference

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Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis.

1 reference

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The mitochondrial permeability transition from in vitro artifact to disease target

1 reference

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14 September 2017

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis

1 reference

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Altering protein turnover in tumor cells: new opportunities for anti-cancer therapies

1 reference

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14 September 2017

Necrotic death as a cell fate

1 reference

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A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

1 reference

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Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

1 reference

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Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

1 reference

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A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death

1 reference

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14 September 2017

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

1 reference

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14 September 2017

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659195

14 September 2017

Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

1 reference

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Proapoptotic BAX and BAK control multiple initiator caspases

1 reference

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Proteasome inhibition as a novel therapeutic target in human cancer.

1 reference

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Mechanism and function of deubiquitinating enzymes

1 reference

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Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

1 reference

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The novel functions of ubiquitination in signaling

1 reference

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

1 reference

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14 September 2017

Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3

1 reference

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14 September 2017

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

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14 September 2017

The ubiquitin system

1 reference

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Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

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1 reference

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Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

1 reference

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1 reference

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1 reference

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

1 reference

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1 reference

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3 September 2018

Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential

1 reference

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Thyroxine induces cyclosporin A-insensitive, Ca2+-dependent reversible permeability transition pore in rat liver mitochondria.

1 reference

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Dual responses of CNS mitochondria to elevated calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/19139105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death in the absence of Bax and Bak

1 reference

https://pubmed.ncbi.nlm.nih.gov/19139105

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M806113200

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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