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The landscape of DNA methylation amid a perfect storm of autism aetiologies.
scientific article published on 06 May 2016
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scholarly article
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Europe PubMed Central
PMCID
4966286
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
review article
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title
The landscape of DNA methylation amid a perfect storm of autism aetiologies
(English)
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stated in
Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
main subject
DNA methylation
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autism
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author
Janine M. LaSalle
series ordinal
2
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Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
author name string
Annie Vogel Ciernia
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1
1 reference
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Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
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4 April 2020
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English
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publication date
6 May 2016
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Europe PubMed Central
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4966286
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
published in
Nature Reviews Neuroscience
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Europe PubMed Central
PMCID
4966286
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
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4 April 2020
volume
17
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Europe PubMed Central
PMCID
4966286
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
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4 April 2020
issue
7
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Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
page(s)
411-423
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Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
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4 April 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nrn.2016.41
0 references
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14 September 2017
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Large-scale methylation domains mark a functional subset of neuronally expressed genes.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
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PubMed Central
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14 September 2017
Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Transcriptomic analysis of autistic brain reveals convergent molecular pathology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Methylation, memory and addiction
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
In search of cellular immunophenotypes in the blood of children with autism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Autism spectrum disorders and autistic traits: a decade of new twin studies
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Somatic coding mutations in human induced pluripotent stem cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Neuronal chromatin dynamics of imprinting in development and disease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Distinct DNA methylation changes highly correlated with chronological age in the human brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Conserved role of intragenic DNA methylation in regulating alternative promoters
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Functional impact of global rare copy number variation in autism spectrum disorders
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Evolving role of MeCP2 in Rett syndrome and autism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Novel variants identified in methyl-CpG-binding domain genes in autistic individuals
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Genomic and epigenetic evidence for oxytocin receptor deficiency in autism
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Human DNA methylomes at base resolution show widespread epigenomic differences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
The methylenetetrahydrofolate reductase 677C-->T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Covalent modification of DNA regulates memory formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Epigenetics of autism spectrum disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
14 September 2017
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
A mixed epigenetic/genetic model for oligogenic inheritance of autism with a limited role for UBE3A
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Tetraspanin Proteins Mediate Cellular Penetration, Invasion, and Fusion Events and Define a Novel Type of Membrane Microdomain
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Phemx, a novel mouse gene expressed in hematopoietic cells maps to the imprinted cluster on distal chromosome 7
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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14 September 2017
Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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29 September 2017
Prenatal Infection and Autism Spectrum Disorders in Childhood: A Population-Based Case-Control Study in Taiwan
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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29 September 2017
Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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27 June 2018
TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
27 June 2018
Increased methylation variation in epigenetic domains across cancer types
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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27 June 2018
Experience-dependent DNA methylation regulates plasticity in the developing visual cortex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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3 September 2018
The DNA methylation landscape of human early embryos.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
3 September 2018
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
3 September 2018
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
3 September 2018
DNA-binding factors shape the mouse methylome at distal regulatory regions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
3 September 2018
Maternal use of folic acid supplements during pregnancy and four-year-old neurodevelopment in a population-based birth cohort
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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3 September 2018
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
retrieved
3 September 2018
Folate status of mothers during pregnancy and mental and psychomotor development of their children at five years of age.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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3 September 2018
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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3 September 2018
Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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3 September 2018
C11orf21, a novel gene within the Beckwith-Wiedemann syndrome region in human chromosome 11p15.5.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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3 September 2018
Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966286
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3 September 2018
DSM-5
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNRN.2016.41
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31 March 2020
Corrigendum: DNA-binding factors shape the mouse methylome at distal regulatory regions
1 reference
stated in
Crossref
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31 March 2020
Identifiers
DOI
10.1038/NRN.2016.41
1 reference
stated in
Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
PMCID
4966286
1 reference
stated in
Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
PubMed ID
27150399
1 reference
stated in
Europe PubMed Central
PMCID
4966286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27150399%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 April 2020
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