(Q37138952)

English

Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor.

scientific article published on 26 February 2016

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26918260%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26918260%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

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inferred from title

pharmacokinetics

1 reference

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monoclonal antibody

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

Charles Boswell

4

1 reference

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9 March 2020

author name string

Rong Deng

1

1 reference

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9 March 2020

Daniela Bumbaca

2

1 reference

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9 March 2020

Cinthia V Pastuskovas

3

1 reference

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9 March 2020

David West

5

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9 March 2020

Kyra J Cowan

6

1 reference

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9 March 2020

Henry Chiu

7

1 reference

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9 March 2020

Jacqueline McBride

8

1 reference

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9 March 2020

Clarissa Johnson

9

1 reference

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9 March 2020

Yan Xin

10

1 reference

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9 March 2020

Hartmut Koeppen

11

1 reference

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9 March 2020

Maya Leabman

12

1 reference

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9 March 2020

Suhasini Iyer

13

1 reference

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9 March 2020

publication date

26 February 2016

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9 March 2020

Monoclonal Antibodies

1 reference

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9 March 2020

8

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9 March 2020

3

1 reference

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9 March 2020

593-603

1 reference

Europe PubMed Central

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9 March 2020

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

1 reference

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1 reference

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PD-1 pathway inhibitors: changing the landscape of cancer immunotherapy

1 reference

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1 reference

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Antitumor activity of targeted and cytotoxic agents in murine subcutaneous tumor models correlates with clinical response

1 reference

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Immunogenicity to therapeutic proteins: impact on PK/PD and efficacy

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1 reference

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1 reference

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Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets

1 reference

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14 September 2017

Maximizing tumour exposure to anti-neuropilin-1 antibody requires saturation of non-tumour tissue antigenic sinks in mice

1 reference

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14 September 2017

Effects of anti-VEGF on predicted antibody biodistribution: roles of vascular volume, interstitial volume, and blood flow

1 reference

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14 September 2017

Effect of immune complex formation on the distribution of a novel antibody to the ovarian tumor antigen CA125.

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14 September 2017

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

1 reference

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14 September 2017

PD-1 and its ligands in tolerance and immunity

1 reference

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14 September 2017

Estimation of dose requirements for sustained in vivo activity of a therapeutic human anti-CD20 antibody

1 reference

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14 September 2017

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer

1 reference

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14 September 2017

Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4966836

14 September 2017

Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

1 reference

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14 September 2017

Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy

1 reference

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1 reference

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29 September 2017

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1 reference

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3 September 2018

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1 reference

https://api.crossref.org/works/10.1080%2F19420862.2015.1136043

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26918260

12 December 2020

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Identifiers

10.1080/19420862.2015.1136043

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26918260%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26918260%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26918260%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

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