(Q26830569)

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Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets

scientific article

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scholarly article

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Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets (English)

1 reference

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

monoclonal antibody

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based on heuristic

inferred from title

author name string

Peter J Bugelski

1

1 reference

Pauline L Martin

2

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language of work or name

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publication date

June 2012

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British Journal of Pharmacology

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166

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3

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823-46

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CD20 deficiency in humans results in impaired T cell-independent antibody responses

1 reference

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The biology of CD20 and its potential as a target for mAb therapy

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Tocilizumab for the treatment of rheumatoid arthritis

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FDA drug approval summary: alemtuzumab as single-agent treatment for B-cell chronic lymphocytic leukemia

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28 September 2017

Rituximab therapy in malignant lymphoma

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The IL-6/sIL-6R complex as a novel target for therapeutic approaches

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28 September 2017

Antiviral antibodies are necessary for control of simian immunodeficiency virus replication

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28 September 2017

A regulatory T cell-dependent novel function of CD25 (IL-2Ralpha) controlling memory CD8(+) T cell homeostasis

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28 September 2017

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28 September 2017

Alemtuzumab in T-cell lymphoproliferative disorders

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28 September 2017

Strategies in the management of alemtuzumab-related side effects

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28 September 2017

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28 September 2017

CD3 deficiencies

1 reference

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28 September 2017

Alefacept: a safety profile

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28 September 2017

Aggravated Lyme carditis in CD11a-/- and CD11c-/- mice

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28 September 2017

Natalizumab for the treatment of multiple sclerosis and Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Anti-erbB-2 antibody trastuzumab in the treatment of HER2-amplified breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Tolerability and safety of rituximab (MabThera).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Anti-adhesion therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

CD4+CD25+ regulatory T cells control induction of autoimmune hemolytic anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Critical period for a teratogenic VLA-4 antagonist: Developmental effects and comparison of embryo drug concentrations of teratogenic and non-teratogenic VLA-4 antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Essential roles of Her2/erbB2 in cardiac development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

A benefit-risk assessment of basiliximab in renal transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Mouse CD20 expression and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Basiliximab: a review of its use as induction therapy in renal transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

The Role of CD28 and CTLA4 in the Function and Homeostasis of CD4 + CD25 + Regulatory T Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Adhesion molecules as therapeutic targets for autoimmune diseases and transplant rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Deaths associated with platelet glycoprotein IIb/IIIa inhibitor treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Modulating T cell responses for the treatment of psoriasis: a focus on efalizumab

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

The mechanisms of action of rituximab in the elimination of tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Platelet glycoprotein IIb/IIIa receptor antagonist (abciximab) inhibited platelet activation and promoted skin flap survival after ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Trastuzumab-associated cardiotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Development of a non-human primate sub-clinical model of heparin-induced thrombocytopenia: platelet responses to human anti-heparin-platelet factor 4 antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

CD25+CD4+ T cells contribute to the control of memory CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Targeting HER2 in other tumor types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

The EGF receptor family as targets for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Pharmacokinetics, pharmacodynamics, and platelet binding of an anti-glycoprotein IIb/IIIa monoclonal antibody (7E3) in the rat: a quantitative rat model of immune thrombocytopenic purpura

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Enhanced survival of grafts genetically endowed with the ability to block CD2 and B7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Glanzmann thrombasthenia: integrin alpha IIb beta 3 deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

CTLA4-Ig: a novel immunosuppressive agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Prevention of acute allograft rejection in nonhuman primate lung transplant recipients: induction with chimeric anti-interleukin-2 receptor monoclonal antibody improves the tolerability and potentiates the immunosuppressive activity of a regimen usi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Insights and questions arising from studies of a mouse model of Glanzmann thrombasthenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Interleukin-4-independent acceleration of cutaneous leishmaniasis in susceptible BALB/c mice following treatment with anti-CTLA4 antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

In vivo or in vitro anti-CD3 epsilon chain monoclonal antibody therapy for the prevention of lethal murine graft-versus-host disease across the major histocompatibility barrier in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

The biology of CD2: adhesion, transmembrane signal, and regulatory receptor of immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Toxicity of OKT3 increases with dosage: a controlled study in renal transplant recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Treatment of acute renal allograft rejection with OKT3 monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

Symptomatic cytomegalovirus disease in the cytomegalovirus antibody seropositive renal transplant recipient treated with OKT3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 September 2017

CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

An integrated analysis of thirteen trials summarizing the long-term safety of alefacept in psoriasis patients who have received up to nine courses of therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

Therapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

A role for alpha4-integrin in the pathology following Semliki Forest virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

alpha 4 integrins and tumor metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

Monoclonal antibodies against human T cell adhesion molecules--modulation of immune function in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

31 May 2018

Abatacept treatment does not exacerbate chronic Mycobacterium tuberculosis infection in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Monoclonal antibodies generated by DNA immunization recognize CD2 from a broad range of primates.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Depletion of natural CD4+CD25+ T regulatory cells with anti-CD25 antibody does not change the course of Pseudomonas aeruginosa-induced acute lung infection in mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Evaluation of a surrogate antibody for preclinical safety testing of an anti-CD11a monoclonal antibody

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Effect of IIb-IIIa glycoprotein inhibitors in a partial limb amputation model submitted to warm ischemia in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Involvement of LFA-1 and ICAM-1 in the herpetic disease resulting from HSV-1 corneal infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

TCR/CD3 mediated stop-signal is decoupled in T-cells from Ctla4 deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

T regulatory cells contribute to the attenuated primary CD8+ and CD4+ T cell responses to herpes simplex virus type 2 in neonatal mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Perturbation of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 results in differential outcomes in cardiac vs islet allograft survival

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

CD52 is synthesized in cumulus cells and secreted into the cumulus matrix during ovulation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Efficacy and safety of single-agent pertuzumab, a human epidermal receptor dimerization inhibitor, in patients with non small cell lung cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

The role of CD4CD25 T cells in autoantibody production in murine lupus.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Progressive multifocal leukoencephalopathy associated with efalizumab use in psoriasis patients

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Anti-CD25 mAb administration prevents spontaneous liver transplant tolerance.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Correlation of pharmacokinetics with the antitumor activity of Cetuximab in nude mice bearing the GEO human colon carcinoma xenograft

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Overexpression of a mutant CTLA4 inhibits T-cell activation and homeostasis-driven expansion.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

The involvement of CD4+CD25+ T cells in the acute phase of Trypanosoma cruzi infection.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Alemtuzumab as treatment of steroid-refractory acute graft-versus-host disease: results of a phase II study.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Differences in wound healing in mice with deficiency of IL-6 versus IL-6 receptor.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Influences of anti-mouse interleukin-6 receptor antibody on immune responses in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Clot lysis in a primate model of peripheral arterial occlusive disease with use of systemic or intraarterial reteplase: addition of abciximab results in improved vessel reperfusion.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Swedish natalizumab (Tysabri) multiple sclerosis surveillance study

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Effect of anti-mouse CD52 monoclonal antibody on mouse intestinal intraepithelial lymphocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

No evidence of JC virus reactivation in natalizumab treated multiple sclerosis patients: an 18 month follow-up study

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

The reverse stop-signal model for CTLA4 function.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Diffuse alveolar hemorrhage following alemtuzumab.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Involvement of neutrophils and natural killer cells in the anti-tumor activity of alemtuzumab in xenograft tumor models.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Modulation of the CD2 receptor and not disruption of the CD2/CD48 interaction is the principal action of CD2-mediated immunosuppression in the rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Novel humanized anti-CD3 antibodies induce a predominantly immunoregulatory profile in human peripheral blood mononuclear cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, ameliorates joint swelling in established monkey collagen-induced arthritis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Developmental immunotoxicology assessment of rituximab in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Effect of molecular therapeutics on liver regeneration in a murine model.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Immunotoxicity profile of natalizumab.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Embryo/fetal development in cynomolgus monkeys exposed to natalizumab, an alpha4 integrin inhibitor.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Postnatal development in cynomolgus monkeys following prenatal exposure to natalizumab, an alpha4 integrin inhibitor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Effects of natalizumab, an alpha4 integrin inhibitor, on the development of Hartley guinea pigs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Effects of natalizumab, an alpha4 integrin inhibitor, on fertility in male and female guinea pigs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Investigation of lymphocyte depletion and repopulation using alemtuzumab (Campath-1H) in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Severe cardiac toxicity after monoclonal antibody therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Abatacept Limits Breach of Self-Tolerance in a Murine Model of Arthritis via Effects on the Generation of T Follicular Helper Cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

CTLA-4-/- mice display T cell-apoptosis resistance resembling that ascribed to autoimmune-prone non-obese diabetic (NOD) mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

CTLA4 engagement is required for induction of murine liver transplant spontaneous tolerance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Effect of interleukin-6 receptor blockage on renal injury in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01811.X

21 January 2018

Effects of cytotoxic T lymphocyte antigen 4 (CTLA4) signaling and locally applied steroid on retinal dysfunction by recoverin, cancer-associated retinopathy antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 November 2018

Cytomegalovirus reactivation during alemtuzumab therapy for chronic lymphocytic leukemia: incidence and treatment with oral ganciclovir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 November 2018

Humanized antibodies against the alpha-chain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 November 2018

A prospective randomized study of prophylactic OKT3 versus equine antithymocyte globulin after heart transplantation--increased morbidity with OKT3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 November 2018

CD2-deficient mice generate virus-specific cytotoxic T lymphocytes upon infection with lymphocytic choriomeningitis virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417412

28 November 2018

Severe erythroderma in a patient under intermittent therapy with efalizumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinically significant liver injury in patients treated with natalizumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of murine alphaIIbbeta3 (GPIIb/IIIa): studies using monoclonal antibodies and beta3-null mice,

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human CD2 is functional in CD2 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple roles for platelet GPIIb/IIIa and alphavbeta3 integrins in tumor growth, angiogenesis, and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic potential of humanized anti-interleukin-6 receptor antibody: antitumor activity in xenograft model of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The course of untreated acute rejection and effect of repeated anti-CD3 monoclonal antibody treatment in rhesus monkey liver transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complications and monitoring of OKT3 therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basiliximab: a review of its use as induction therapy in renal transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppression of collagen-induced arthritis in mice with an anti-IL-2 receptor antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

7E3 F(ab')2, an effective antagonist of rat alphaIIbbeta3 and alphavbeta3, blocks in vivo thrombus formation and in vitro angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+CD25+ T cell depletion impairs tolerance induction in a murine model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycoprotein IIB/IIIA-inhibition and microcirculatory alterations during experimental endotoxemia--an intravital microscopic study in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of anti-CD2 antibodies on the differentiation of mouse thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of CD4+CD25+ T cells in the development of experimental murine allergic conjunctivitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD25+ regulatory T cell inhibition enhances vaccine-induced immunity to neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fatal case of alemtuzumab-associated interstitial pneumonitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chimeric monoclonal antibody abciximab: a systematic review of its safety in contemporary practice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of psoriasis with efalizumab in patients with hepatitis C viral infection: report of five cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking VLA-4 prevents progression of experimental crescentic glomerulonephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of monoclonal antibodies to adhesion molecules on eosinophilic myocarditis in Toxocara canis-infected CBA/J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of integrin VLA-4 prevents inflammation and matrix metalloproteinase expression in a murine model of accelerated collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical studies of allograft tolerance in rhesus monkeys: a novel anti-CD3-immunotoxin given peritransplant with donor bone marrow induces operational tolerance to kidney allografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of tumour metastasis in a murine osteosarcoma model with anti-CD25 monoclonal antibody treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of proteoglycan-induced arthritis by anti-CD20 B Cell depletion therapy is mediated by reduction in autoantibodies and CD4+ T cell reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function and Regulation of the Murine Lymphocyte CD2 Receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-modulation of CD2 delays deletion of superantigen-responsive T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An approach to natalizumab hypersensitivity: a case series of induction of tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of mortality and lymphadenopathy in MRL-lpr/lpr mice treated with nonmitogenic anti-CD3 monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The repopulation capacity of bone marrow grafts following pretreatment with monoclonal antibodies against T lymphocytes in rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation of allograft and xenograft survival in mice by anti-CD2 monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daclizumab: humanized monoclonal antibody to the interleukin-2 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different role for mouse and human CD3delta/epsilon heterodimer in preT cell receptor (preTCR) function: human CD3delta/epsilon heterodimer restores the defective preTCR function in CD3gamma- and CD3gammadelta-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, improved anemia in monkey arthritis by suppressing IL-6-induced hepcidin production

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using an analogous monoclonal antibody to evaluate the reproductive and chronic toxicity potential for a humanized anti-TNFalpha monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-fed db/db mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abolition of in vivo platelet thrombus formation in primates with monoclonal antibodies to the platelet GPIIb/IIIa receptor. Correlation with bleeding time, platelet aggregation, and blockade of GPIIb/IIIa receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: prevention by high doses of methylprednisolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of an immunomodulatory LFA3-IgG1 fusion protein on nonhuman primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basiliximab, mechanism of action and pharmacological properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-interleukin 6 (IL-6) receptor antibody suppresses Castleman's disease like symptoms emerged in IL-6 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular basis of the resistance of newborn mice to the pathogenic effects of anti-CD3 treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell depletion of Cercopithecus aethiops monkey bone marrow with Campath-1 monoclonal antibody and complement

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inheritance of a Macaca fascicularis red cell antigen detected by CAMPATH-1 antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/22168282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2011.01811.X

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1 reference

PubMed publication ID

1 reference

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