(Q37140623)

18 August 2017

1 reference

title

Molecular mechanisms that could contribute to prolonged effectiveness of PDE5 inhibitors to improve erectile function (English)

1 reference

18 August 2017

S H Francis

1

1 reference

PubMed ID

18418391

18 August 2017

G Z Morris

series ordinal

2

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PubMed ID

18418391

18 August 2017

J D Corbin

series ordinal

3

1 reference

18 August 2017

17 April 2008

1 reference

International Journal of Impotence Research

18 August 2017

1 reference

18 August 2017

20

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18 August 2017

333-342

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18 August 2017

4

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https://scigraph.springernature.com/pub.10.1038/ijir.2008.4

18 August 2017

0 references

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Allosteric sites of phosphodiesterase-5 (PDE5). A potential role in negative feedback regulation of cGMP signaling in corpus cavernosum

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Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation

21 January 2018

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21 January 2018

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PDE5 inhibitors beyond erectile dysfunction

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21 January 2018

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21 January 2018

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STa and cGMP stimulate CFTR translocation to the surface of villus enterocytes in rat jejunum and is regulated by protein kinase G

21 January 2018

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21 January 2018

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Allosteric sites of phosphodiesterase-5 sequester cyclic GMP.

21 January 2018

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cGMP-dependent protein kinase protects cGMP from hydrolysis by phosphodiesterase-5

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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7 January 2021

Mechanisms of NO/cGMP-dependent vasorelaxation

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https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Molecular biology and pharmacology of PDE-5-inhibitor therapy for erectile dysfunction.

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Potential roles of conserved amino acids in the catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Contribution of phosphodiesterase isoenzymes and cyclic nucleotide efflux to the regulation of cyclic GMP levels in aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Phosphorylation of phosphodiesterase-5 is promoted by a conformational change induced by sildenafil, vardenafil, or tadalafil

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Arginine 75 in the pseudosubstrate sequence of type Ibeta cGMP-dependent protein kinase is critical for autoinhibition, although autophosphorylated serine 63 is outside this sequence

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Autophosphorylation of cGMP‐dependent protein kinase is stimulated only by occupancy of one the two cGMP binding sites

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Conversion of phosphodiesterase-5 (PDE5) catalytic site to higher affinity by PDE5 inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Toxicokinetics of [14C]hexafluoroacetone in the rat

1 reference

https://api.crossref.org/works/10.1038%2FIJIR.2008.4

7 January 2021

Identifiers

DOI

10.1038/IJIR.2008.4

1 reference

18 August 2017

1 reference

PubMed ID

18418391