(Q37145037)

English

Efficacy of opsonic and nonopsonic serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibodies against intranasal challenge with Streptococcus pneumoniae in mice

scientific article published on 21 January 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Efficacy of opsonic and nonopsonic serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibodies against intranasal challenge with Streptococcus pneumoniae in mice (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1 reference

based on heuristic

inferred from title

Streptococcus pneumoniae

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

monoclonal antibody

1 reference

based on heuristic

inferred from title

Thomas R. Kozel

4

1 reference

Europe PubMed Central

PMC publication ID

10 December 2018

Liise-anne Pirofski

5

object named as

Liise-Anne Pirofski

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Haijun Tian

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Sarah Weber

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Peter Thorkildson

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

21 January 2009

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Infection and Immunity

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

77

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1502-1513

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

THE PROTECTIVE ACTION OF TYPE I ANTIPNEUMOCOCCUS SERUM IN MICE : I. THE QUANTITATIVE ASPECTS OF THE MOUSE PROTECTION TEST

1 reference

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Antibody to the type 3 capsule facilitates immune adherence of pneumococci to erythrocytes and augments their transfer to macrophages

1 reference

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Pneumococcal necrotizing pneumonia in Utah: does serotype matter?

1 reference

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6 September 2017

Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis

1 reference

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6 September 2017

Fcgamma receptors as regulators of immune responses

1 reference

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Phase 1 trial of a 13-valent pneumococcal conjugate vaccine in healthy adults

1 reference

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Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

1 reference

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6 September 2017

Decline in pneumonia admissions after routine childhood immunisation with pneumococcal conjugate vaccine in the USA: a time-series analysis

1 reference

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6 September 2017

A human monoclonal immunoglobulin M reduces bacteremia and inflammation in a mouse model of systemic pneumococcal infection

1 reference

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6 September 2017

Influence of neutropenia on the course of serotype 8 pneumococcal pneumonia in mice

1 reference

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6 September 2017

Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006).

1 reference

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FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin

1 reference

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6 September 2017

Pneumococcal capsular polysaccharide vaccine-mediated protection against serotype 3 Streptococcus pneumoniae in immunodeficient mice

1 reference

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6 September 2017

Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule

1 reference

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6 September 2017

Use of opsonophagocytosis for serological evaluation of pneumococcal vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Correlation of molecular characteristics, isotype, and in vitro functional activity of human antipneumococcal monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Fcgamma receptors: old friends and new family members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Streptococcus pneumoniae : Epidemiology, Risk Factors, and Clinical Features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

THP-1 monocytes up-regulate intercellular adhesion molecule 1 in response to pneumolysin from Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Modulation of the lung inflammatory response to serotype 8 pneumococcal infection by a human immunoglobulin m monoclonal antibody to serotype 8 capsular polysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

A peptide mimotope of type 8 pneumococcal capsular polysaccharide induces a protective immune response in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Depletion of complement has distinct effects on the primary and secondary antibody responses to a conjugate of pneumococcal serotype 14 capsular polysaccharide and a T-cell-dependent protein carrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

The pathogenesis of fatal outcome in murine pulmonary aspergillosis depends on the neutrophil depletion strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

VBASE2, an integrative V gene database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Serotype-specific mortality from invasive Streptococcus pneumoniae disease revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

The 23-valent pneumococcal polysaccharide vaccine. Part I. Efficacy of PPV in the elderly: a comparison of meta-analyses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

The innate immune response to pneumococcal lung infection: the untold story.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Modulation of polymorphonuclear cell interleukin-8 secretion by human monoclonal antibodies to type 8 pneumococcal capsular polysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Effectiveness of pneumococcal polysaccharide vaccine in older adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Contribution of epitope specificity to the binding of monoclonal antibodies to the capsule of Cryptococcus neoformans and the soluble form of its major polysaccharide, glucuronoxylomannan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Structure-function relationships for human antibodies to pneumococcal capsular polysaccharide from transgenic mice with human immunoglobulin Loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Production of protective human antipneumococcal antibodies by transgenic mice with human immunoglobulin loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Opsonic and nonopsonic interactions of C3 with Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Molecular and functional characteristics of a protective human monoclonal antibody to serotype 8 Streptococcus pneumoniae capsular polysaccharide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Use of highly encapsulated Streptococcus pneumoniae strains in a flow-cytometric assay for assessment of the phagocytic capacity of serotype-specific antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Standardization of an opsonophagocytic assay for the measurement of functional antibody activity against Streptococcus pneumoniae using differentiated HL-60 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Opsonization of Cryptococcus neoformans by human anticryptococcal glucuronoxylomannan antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Pneumococcal polysaccharide vaccine efficacy. An evaluation of current recommendations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

FcR gamma chain deletion results in pleiotrophic effector cell defects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Hereditary properdin deficiency in three families of Tunisian Jews

1 reference

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6 September 2017

Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

6 September 2017

Mechanisms of host defense against infection with Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

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The monoclonal antibody against the major diagnostic antigen of Paracoccidioides brasiliensis mediates immune protection in infected BALB/c mice challenged intratracheally with the fungus.

1 reference

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14 September 2017

Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998-2004.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

14 September 2017

Promotion of opsonization by antibodies and phagocytosis of Gram-positive bacteria by a bifunctional polyacrylamide

1 reference

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Trends in antimicrobial drug development: implications for the future

1 reference

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14 September 2017

Serum therapy revisited: animal models of infection and development of passive antibody therapy

1 reference

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14 September 2017

Perspective: hypothesis: serum IgG antibody is sufficient to confer protection against infectious diseases by inactivating the inoculum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

14 September 2017

Approach to validating an opsonophagocytic assay for Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

29 September 2017

Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb

1 reference

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27 June 2018

Fc gamma receptors regulate immune activation and susceptibility during Mycobacterium tuberculosis infection

1 reference

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27 June 2018

Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

27 June 2018

Correlation of opsonophagocytosis and passive protection assays using human anticapsular antibodies in an infant mouse model of bacteremia for Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

27 June 2018

Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae--and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization--in HIV-Infected and HIV-uninfected childre

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Invasive pneumococcal disease in solid organ transplant recipients--10-year prospective population surveillance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Effect of prior pneumococcal vaccination on clinical outcome of hospitalized adults with community-acquired pneumococcal pneumonia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Impact of the pneumococcal conjugate vaccine on pneumococcal parapneumonic empyema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Streptococcus pneumoniae-associated human macrophage apoptosis after bacterial internalization via complement and Fcgamma receptors correlates with intracellular bacterial load.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Neutropenia alters lung cytokine production in mice and reduces their susceptibility to pulmonary cryptococcosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Role of leukocyte immunoglobuin G receptors in vaccine-induced immunity to Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Immune-mediated phagocytosis and killing of Streptococcus pneumoniae are associated with direct and bystander macrophage apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

The protective efficacy of polyvalent pneumococcal polysaccharide vaccine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663166

3 September 2018

Development of an opsonin inhibition assay for evaluation of complex polysaccharide protective epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of pneumococcal vaccine against death by pneumonia in elderly subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice Deficient for the Complement Factor B Develop and Reproduce Normally

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pneumococcal pneumonia and bacteremia model in mice for the analysis of protective antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non-typable Haemophilus influenzae: a randomised double-blind efficacy study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct and indirect effects of routine vaccination of children with 7-valent pneumococcal conjugate vaccine on incidence of invasive pneumococcal disease--United States, 1998-2003

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of humoral and phagocytic defenses against Streptococcus pneumoniae serotypes 1 and 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agglutination and phagocytosis of pneumococci by immunoglobulin G antibodies of restricted heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing characteristics of invasive pneumococcal disease in Metropolitan Atlanta, Georgia, after introduction of a 7-valent pneumococcal conjugate vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of the immune response following pneumococcal PD conjugate vaccination

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of serotype-specific IgG concentration, IgG subclasses and relative antibody avidity to opsonophagocytic activity against Streptococcus pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiplex opsonophagocytosis assay (MOPA): a useful tool for the monitoring of the 7-valent pneumococcal conjugate vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of cross-reactive antibodies with low opsonophagocytic activity for Streptococcus pneumoniae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central role of complement in passive protection by human IgG1 and IgG2 anti-pneumococcal antibodies in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies reveal additional epitopes of serotype D Cryptococcus neoformans capsular glucuronoxylomannan that elicit protective antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mouse complement by monoclonal mouse antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing epidemiology of invasive pneumococcal disease among older adults in the era of pediatric pneumococcal conjugate vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19168739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.01075-08

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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