(Q37145116)

18 August 2017

1 reference

title

Endosomal sorting complex required for transport proteins in cancer pathogenesis, vesicular transport, and non-endosomal functions (English)

1 reference

18 August 2017

0 references

Nobuyuki Tanaka

1

1 reference

PubMed ID

18429951

18 August 2017

Masanao Kyuuma

series ordinal

2

1 reference

PubMed ID

18429951

18 August 2017

Kazuo Sugamura

series ordinal

3

1 reference

18 August 2017

22 April 2008

1 reference

18 August 2017

1 reference

18 August 2017

99

1 reference

18 August 2017

7

1 reference

18 August 2017

1293-1303

1 reference

The biogenesis of multivesicular endosomes

18 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

21 January 2018

A protein's final ESCRT.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Endosomal compartmentalization in three dimensions: Implications for membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Receptor downregulation and multivesicular-body sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The ESCRT complexes: structure and mechanism of a membrane-trafficking network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The emerging shape of the ESCRT machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Protein sorting into multivesicular endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Ubiquitylation and cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Regulating protein degradation by ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Protein regulation by monoubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Ubiquitin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Ubiquitin interactions of NZF zinc fingers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Endocytosis: the DUB version

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

AMSH, an ESCRT-III associated enzyme, deubiquitinates cargo on MVB/late endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hrs is associated with STAM, a signal-transducing adaptor molecule. Its suppressive effect on cytokine-induced cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Vps27 recruits ESCRT machinery to endosomes during MVB sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hse1, a component of the yeast Hrs-STAM ubiquitin-sorting complex, associates with ubiquitin peptidases and a ligase to control sorting efficiency into multivesicular bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hrs regulates early endosome fusion by inhibiting formation of an endosomal SNARE complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

ESCRTing cell proliferation off the beaten path: lessons from the drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Structural and functional organization of the ESCRT-I trafficking complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

AAA+ proteins: have engine, will work

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Structural and mechanistic studies of VPS4 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Vta1p and Vps46p regulate the membrane association and ATPase activity of Vps4p at the yeast multivesicular body

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Structure/function analysis of four core ESCRT-III proteins reveals common regulatory role for extreme C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Defective downregulation of receptor tyrosine kinases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Separate endocytic pathways of kinase-defective and -active EGF receptor mutants expressed in same cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Clathrin-independent endocytosis of ubiquitinated cargos

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

EGF receptor ubiquitination is not necessary for its internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Epidermal growth factor receptor fate is controlled by Hrs tyrosine phosphorylation sites that regulate Hrs degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Regulating the regulator: negative regulation of Cbl ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Degradation of HER2 by Cbl-based chimeric ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Down-regulation of MET, the receptor for hepatocyte growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Endosomal dynamics of Met determine signaling output

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Protein degradation: four E3s for the notch pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hrs mediates downregulation of multiple signalling receptors in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Inhibition of tumor growth and metastasis by depletion of vesicular sorting protein Hrs: its regulatory role on E-cadherin and beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Cloning and characterization of ELL-associated proteins EAP45 and EAP20. a role for yeast EAP-like proteins in regulation of gene expression by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Identification and purification of the Holo-ELL complex. Evidence for the presence of ELL-associated proteins that suppress the transcriptional inhibitory activity of ELL

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

bicoid RNA localization requires specific binding of an endosomal sorting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Exosome secretion: the art of reutilizing nonrecycled proteins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

The Protein Network of HIV Budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Cell cycle arrest and cell death are controlled by p53-dependent and p53-independent mechanisms in Tsg101-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

Oiling the wheels of the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00825.X

10.1111/J.1349-7006.2008.00825.X

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference

PubMed ID

18429951