(Q37151978)

18 August 2017

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title

Nox enzymes in immune cells (English)

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18 August 2017

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William M Nauseef

1

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18 August 2017

publication date

1 May 2008

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Seminars in Immunopathology

18 August 2017

published in

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18 August 2017

volume

30

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18 August 2017

issue

3

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18 August 2017

page(s)

195-208

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https://scigraph.springernature.com/pub.10.1007/s00281-008-0117-4

18 August 2017

exact match

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cites work

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

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12 December 2020

Novel Human Homologues of p47 and p67 Participate in Activation of Superoxide-producing NADPH Oxidases

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12 December 2020

Cell transformation by the superoxide-generating oxidase Mox1

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12 December 2020

Mechanism of hydrogen peroxide formation catalyzed by NADPH oxidase in thyroid plasma membrane

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12 December 2020

[Leukocyte metabolism in phagocytosis]

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12 December 2020

The distribution and function of peroxidases in the respiratory tract.

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12 December 2020

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

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12 December 2020

Hypochlorite-induced oxidation of amino acids, peptides and proteins.

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12 December 2020

How human neutrophils kill and degrade microbes: an integrated view

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12 December 2020

Phosphorylation of the oxidase-related 48K phosphoprotein family in the unusual autosomal cytochrome-negative and X-linked cytochrome-positive types of chronic granulomatous disease

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12 December 2020

Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

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12 December 2020

Direct involvement of the small GTPase Rac in activation of the superoxide-producing NADPH oxidase Nox1.

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12 December 2020

The Nox family of NAD(P)H oxidases: host defense and beyond

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12 December 2020

Lactoperoxidase and hydrogen peroxide metabolism in the airway

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12 December 2020

Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation

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12 December 2020

Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system

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12 December 2020

Transcellular thiocyanate transport by human airway epithelia

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12 December 2020

Purification of cytochrome b-245 from human neutrophils

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12 December 2020

Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system

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12 December 2020

The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis

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12 December 2020

Dual oxidase2 is expressed all along the digestive tract

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12 December 2020

Chloramines as intermediates of oxidation reaction of amino acids by myeloperoxidase.

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12 December 2020

Purification of the 47 kDa phosphoprotein associated with the NADPH oxidase of human neutrophils

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12 December 2020

Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease

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12 December 2020

Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis

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12 December 2020

Novel cytochrome b system in phagocytic vacuoles of human granulocytes

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12 December 2020

Monoclonal antibody 7D5 raised to cytochrome b558 of human neutrophils: immunocytochemical detection of the antigen in peripheral phagocytes of normal subjects, patients with chronic granulomatous disease, and their carrier mothers

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12 December 2020

Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity

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12 December 2020

Innate host defense: Nox and Duox on phox's tail

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12 December 2020

The enzymic reduction and kinetics of oxidation of cytochrome b-245 of neutrophils

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12 December 2020

Reactive oxygen species signaling in response to pathogens

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12 December 2020

Absence of a newly described cytochrome b from neutrophils of patients with chronic granulomatous disease

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12 December 2020

The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes

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12 December 2020

HaCaT Keratinocytes Overexpressing the S100 Proteins S100A8 and S100A9 Show Increased NADPH Oxidase and NF-κB Activities

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12 December 2020

Hypochlorous acid and myeloperoxidase-catalyzed oxidation of iron-sulfur clusters in bacterial respiratory dehydrogenases

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12 December 2020

Brominating oxidants generated by human eosinophils

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12 December 2020

H2O2 release from human granulocytes during phagocytosis. Relationship to superoxide anion formation and cellular catabolism of H2O2: studies with normal and cytochalasin B-treated cells

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12 December 2020

The PX domain as a novel phosphoinositide- binding module

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12 December 2020

A novel host defense system of airways is defective in cystic fibrosis

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12 December 2020

Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism

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12 December 2020

Electron and proton transport by NADPH oxidases

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12 December 2020

Regulation and termination of NADPH oxidase activity

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12 December 2020

Unsaturated fatty acids stimulate NADPH-dependent superoxide production by cell-free system derived from macrophages

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12 December 2020

Processing and Maturation of Flavocytochromeb558Include Incorporation of Heme as a Prerequisite for Heterodimer Assembly

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12 December 2020

Role of myeloperoxidase in the respiratory burst of human neutrophils

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12 December 2020

Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox

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12 December 2020

Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system

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12 December 2020

The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators

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12 December 2020

How antibiotics can make us sick: the less obvious adverse effects of antimicrobial chemotherapy

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12 December 2020

Novel mechanism of activation of NADPH oxidase 5. calcium sensitization via phosphorylation.

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12 December 2020

Regulation of Nox and Duox enzymatic activity and expression

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12 December 2020

Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases

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12 December 2020

A fatal granulomatous disease of childhood; the clinical, pathological, and laboratory features of a new syndrome.

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12 December 2020

NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox

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12 December 2020

The signaling pathway involved in neutrophil elastase stimulated MUC1 transcription

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12 December 2020

Effects of oxygen tension and pH on the respiratory burst of human neutrophils

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12 December 2020

A new cytochrome in neurophilic granules of rabbit leucocyte.

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12 December 2020

Lactoperoxidase and human airway host defense

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12 December 2020

Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3

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12 December 2020

Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells

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12 December 2020

Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells

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12 December 2020

Expression of mRNA for ROS-generating NADPH oxidases in the aging stomach

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12 December 2020

Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor

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12 December 2020

Retrovirus-mediated reconstitution of respiratory burst activity in X-linked chronic granulomatous disease cells

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12 December 2020

Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds

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12 December 2020

Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit

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12 December 2020

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

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12 December 2020

In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood

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12 December 2020

Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA.

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12 December 2020

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

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12 December 2020

Improved superoxide-generating ability by interferon gamma due to splicing pattern change of transcripts in neutrophils from patients with a splice site mutation in CYBB gene.

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12 December 2020

Electrophysiology of the phagocyte respiratory burst. Focus on "Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity".

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12 December 2020

Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes. Potentiometric studies of a mutant form of gp91phox

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12 December 2020

Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis

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12 December 2020

Chlorinating Ability of Human Phagocytosing Leucocytes

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12 December 2020

Superoxide production by digitonin-stimulated guinea pig granulocytes. The effects of N-ethyl maleimide, divalent cations; and glycolytic and mitochondrial inhibitors on the activation of the superoxide generating system

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12 December 2020

The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels

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12 December 2020

Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components

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12 December 2020

NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells

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12 December 2020

Regulated hydrogen peroxide production by Duox in human airway epithelial cells

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12 December 2020

Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.

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12 December 2020

Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia.

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12 December 2020

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12 December 2020

Oxygen consumption of phagocytizing cells in human leukocyte and granulocyte preparations: a comparative study

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12 December 2020

Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome: implications for microbial killing

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12 December 2020

NOX family NADPH oxidases: not just in mammals

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12 December 2020

The respiratory burst oxidase of fertilization. A physiological target for regulation by protein kinase C.

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12 December 2020

Protein phosphorylation associated with synergistic stimulation of neutrophils

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12 December 2020

Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

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12 December 2020

Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas

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12 December 2020

Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells

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12 December 2020

Role of myeloperoxidase-mediated antimicrobial systems in intact leukocytes

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12 December 2020

Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras

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12 December 2020

Reactive oxygen species modulate Anopheles gambiae immunity against bacteria and Plasmodium

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12 December 2020

Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304.

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12 December 2020

Mechanisms of expression of NADPH oxidase components in human cultured monocytes: role of cytokines and transcriptional regulators involved

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12 December 2020

[Electron microscopic and biochemical study of the neutrophilic granules from leucocytes]

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12 December 2020

Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense

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12 December 2020

The membrane-associated component of the amphiphile-activated, cytosol-dependent superoxide-forming NADPH oxidase of macrophages is identical to cytochrome b559

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12 December 2020

The peroxidase-thiocyanate-hydrogen peroxide antimicrobial system

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12 December 2020

Mutagenesis of p22(phox) histidine 94. A histidine in this position is not required for flavocytochrome b558 function

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12 December 2020

The host defense of Drosophila melanogaster

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12 December 2020

Free radical generation and coupled thiol oxidation by lactoperoxidase/SCN-/H2O2

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12 December 2020

The oxidative burst at fertilization is dependent upon activation of the dual oxidase Udx1.

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12 December 2020

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

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12 December 2020

Analysis of human phagocyte flavocytochrome b(558) by mass spectrometry

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12 December 2020

Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease

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12 December 2020

The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems

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12 December 2020

A direct role for dual oxidase in Drosophila gut immunity

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12 December 2020

The O2(-) -forming oxidase responsible for the respiratory burst in human neutrophils. Properties of the solubilized enzyme

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12 December 2020

A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes

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12 December 2020

NADPH oxidases in lung biology and pathology: host defense enzymes, and more

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12 December 2020

Activation of protein kinase C in neutrophil cytoplasts. Localization of protein substrates and possible relationship with stimulus-response coupling

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12 December 2020

Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease

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12 December 2020

Current molecular models for NADPH oxidase regulation by Rac GTPase

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12 December 2020

The cytosolic activating factors p47phox and p67phox have distinct roles in the regulation of electron flow in NADPH oxidase

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12 December 2020

Phage display epitope mapping of human neutrophil flavocytochrome b558. Identification of two juxtaposed extracellular domains

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12 December 2020

Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid

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12 December 2020

Regulation of interleukin-8 via an airway epithelial signaling cascade

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12 December 2020

Solution structure of the PX domain, a target of the SH3 domain

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12 December 2020

Oxidation of chloride and thiocyanate by isolated leukocytes

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12 December 2020

Biosynthesis of the phagocyte NADPH oxidase cytochrome b558. Role of heme incorporation and heterodimer formation in maturation and stability of gp91phox and p22phox subunits

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12 December 2020

Reactions of superoxide with myeloperoxidase

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12 December 2020

Lactoperoxidase-catalyzed oxidation of thiocyanate by hydrogen peroxide: 15N nuclear magnetic resonance and optical spectral studies

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12 December 2020

Bromination and chlorination reactions of myeloperoxidase at physiological concentrations of bromide and chloride

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12 December 2020

Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

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12 December 2020

Lactoperoxidase, peroxide, thiocyanate antimicrobial system: correlation of sulfhydryl oxidation with antimicrobial action

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12 December 2020

NADPH and NADH oxidation by guinea pig polymorphonuclear leucocytes

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12 December 2020

Interferon-gamma improves splicing efficiency of CYBB gene transcripts in an interferon-responsive variant of chronic granulomatous disease due to a splice site consensus region mutation

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12 December 2020

Production of superoxide anion by an nadph-oxidase from rat pulmonary macrophages

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12 December 2020

Further evidence for the involvement of a phosphoprotein in the respiratory burst oxidase of human neutrophils

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12 December 2020

NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin

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12 December 2020

Origin, structure, and biological activities of peroxidases in human saliva

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12 December 2020

Strboh A homologue of NADPH oxidase regulates wound-induced oxidative burst and facilitates wound-healing in potato tubers

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12 December 2020

p22-phox-deficient chronic granulomatous disease: reconstitution by retrovirus-mediated expression and identification of a biosynthetic intermediate of gp91-phox.

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12 December 2020

The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex

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12 December 2020

Physiology and pathophysiology of the DUOXes

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12 December 2020

Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location

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12 December 2020

Chemiluminescence and superoxide production by myeloperoxidase-deficient leukocytes

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12 December 2020

Nox1-dependent reactive oxygen generation is regulated by Rac1

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12 December 2020

A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease

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12 December 2020

Relationship of protein phosphorylation to the activation of the respiratory burst in human neutrophils. Defects in the phosphorylation of a group of closely related 48-kDa proteins in two forms of chronic granulomatous disease.

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12 December 2020

Reactive oxygen species regulate Pseudomonas aeruginosa lipopolysaccharide-induced MUC5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alpha signaling pathways in human airway epithelial cells

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12 December 2020

Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity

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12 December 2020

New phenotypes in thyroid dyshormonogenesis: hypothyroidism due to DUOX2 mutations

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12 December 2020

Phosphorylation of cytosolic proteins by resting and activated human neutrophils

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12 December 2020

Myeloperoxidase: friend and foe

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12 December 2020

Patients with chronic granulomatous disease have a reduced peripheral blood memory B cell compartment.

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12 December 2020

Generation of reactive oxygen species by fungal NADPH oxidases is required for rice blast disease

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12 December 2020

Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.

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12 December 2020

Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5

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12 December 2020

Isolation and characterization of a peroxidase from the airway

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12 December 2020

Studies of the Metabolic Activity of Leukocytes from Patients with a Genetic Abnormality of Phagocytic Function*

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12 December 2020

Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils

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12 December 2020

Role of Nox family NADPH oxidases in host defense

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12 December 2020

Heme-ligating histidines in flavocytochrome b(558): identification of specific histidines in gp91(phox).

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12 December 2020

Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease.

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12 December 2020

Location of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b558, to the extracellular peptide portion of primate gp91phox

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12 December 2020

Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558.

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12 December 2020

Respiratory burst oxidase of fertilization

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12 December 2020

NADPH oxidase deficiency in X-linked chronic granulomatous disease

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12 December 2020

The Ca2+/NADPH-dependent H2O2 generator in thyroid plasma membrane: inhibition by diphenyleneiodonium

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12 December 2020

Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity

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12 December 2020

Sensitive immunometric assays for secretory peroxidase and myeloperoxidase in human saliva

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12 December 2020

A Controlled Trial of Interferon Gamma to Prevent Infection in Chronic Granulomatous Disease

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12 December 2020

Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes

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12 December 2020

Reactive oxygen species produced by NADPH oxidase regulate plant cell growth

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12 December 2020

Electron transfer in the superoxide-generating NADPH oxidase complex reconstituted in vitro

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12 December 2020

Chlorination of bacterial and neutrophil proteins during phagocytosis and killing of Staphylococcus aureus

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12 December 2020

Myeloperoxidase-mediated inhibition of microbial respiration: damage to Escherichia coli ubiquinol oxidase

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12 December 2020

Lactoperoxidase-catalyzed oxidation of thiocyanate ion: a carbon-13 nuclear magnetic resonance study of the oxidation products

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12 December 2020

Biosynthesis of flavocytochrome b558 . gp91(phox) is synthesized as a 65-kDa precursor (p65) in the endoplasmic reticulum.

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12 December 2020

Hydrogen peroxide-scavenging properties of normal human airway secretions.

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12 December 2020

NADPH oxidases: new kids on the block

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12 December 2020

Continuous phosphorylation of both the 47 and the 49 kDa proteins occurs during superoxide production by neutrophils

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12 December 2020

Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase.

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12 December 2020

NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

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12 December 2020

Termination of the Respiratory Burst in Human Neutrophils

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12 December 2020

Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation

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12 December 2020

Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase

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12 December 2020

Assembly of the phagocyte NADPH oxidase

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12 December 2020

Two forms of autosomal chronic granulomatous disease lack distinct neutrophil cytosol factors.

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12 December 2020

Antibacterial effect of lactoperoxidase and myeloperoxidase against Bacillus cereus

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12 December 2020

Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5).

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12 December 2020

Reactions of myeloperoxidase-derived oxidants with biological substrates: gaining chemical insight into human inflammatory diseases

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12 December 2020

The p40phox and p47phox PX domains of NADPH oxidase target cell membranes via direct and indirect recruitment by phosphoinositides.

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12 December 2020

The p67(phox) activation domain regulates electron flow from NADPH to flavin in flavocytochrome b(558)

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12 December 2020

Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein

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12 December 2020

Studies on the labile, stable Nadi oxidase and peroxidase staining reactions in the isolated particles of horse granulocyte

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12 December 2020

Two novel proteins activate superoxide generation by the NADPH oxidase NOX1

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12 December 2020

Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

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12 December 2020

Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.

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12 December 2020

Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3

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12 December 2020

Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells

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12 December 2020

Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase

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12 December 2020

NADPH oxidase-dependent acid production in airway epithelial cells

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12 December 2020

Changes in protein phosphorylation in guinea pig polymorphonuclear leukocytes by treatment with membrane-perturbing agents which stimulate superoxide anion production

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12 December 2020

NOX3, a superoxide-generating NADPH oxidase of the inner ear

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12 December 2020

Functional and metabolic properties of polymorphonuclear leucocytes. I. Observations on the requirements and consequences of particle ingestion

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12 December 2020

Long-lived oxidants generated by human neutrophils: characterization and bioactivity

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12 December 2020

Production of reactive oxygen species by hemocytes from the cattle tick Boophilus microplus.

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12 December 2020

Two modes of pathogen recognition by plants

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12 December 2020

Mutation of the Cyba gene encoding p22phox causes vestibular and immune defects in mice

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12 December 2020

Absence of both cytochrome b−245 subunits from neutrophils in X-linked chronic granulomatous disease

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12 December 2020

Charge compensation during the phagocyte respiratory burst

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12 December 2020

Duox2 exhibits potent heme peroxidase activity in human respiratory tract epithelium.

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12 December 2020

Free radical generation during the activation of hemolymph prepared from the homopteran Dactylopius coccus.

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12 December 2020

Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245

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12 December 2020

NAD(P)H-dependent superoxide production by phagocytic vesicles from guinea pig and human granulocytes

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12 December 2020

NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation.

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12 December 2020

Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

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12 December 2020

PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation

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12 December 2020

Role of NF-κB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-α

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12 December 2020

10.1007/S00281-008-0117-4

Identifiers

DOI

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18 August 2017

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