(Q37153996)

English

PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease

scientific article published on April 2008

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease (English)

1 reference

Europe PubMed Central

18 August 2017

Parkinson's disease

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Arnulfo Quesada

1

1 reference

Europe PubMed Central

18 August 2017

Becky Y Lee

2

1 reference

Europe PubMed Central

18 August 2017

Paul E Micevych

3

1 reference

Europe PubMed Central

18 August 2017

publication date

1 April 2008

1 reference

Europe PubMed Central

18 August 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

Developmental Neurobiology

1 reference

Europe PubMed Central

18 August 2017

68

1 reference

Europe PubMed Central

18 August 2017

5

1 reference

Europe PubMed Central

18 August 2017

632-644

1 reference

Europe PubMed Central

18 August 2017

Distribution and localization patterns of estrogen receptor-beta and insulin-like growth factor-1 receptors in neurons and glial cells of the female rat substantia nigra: localization of ERbeta and IGF-1R in substantia nigra

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

6 September 2017

Implications for estrogens in Parkinson's disease: an epidemiological approach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

6 September 2017

Estrogen receptor protein interaction with phosphatidylinositol 3-kinase leads to activation of phosphorylated Akt and extracellular signal-regulated kinase 1/2 in the same population of cortical neurons: a unified mechanism of estrogen action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

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Dose and temporal pattern of estrogen exposure determines neuroprotective outcome in hippocampal neurons: therapeutic implications

1 reference

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Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

1 reference

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6 September 2017

Is there a connection between estrogen and Parkinson's disease?

1 reference

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Are men at greater risk for Parkinson's disease than women?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

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Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice

1 reference

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Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity.

1 reference

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Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites

1 reference

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Cell type-specificity of nonclassical estrogen signaling in the developing midbrain

1 reference

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Function and regulation of CREB family transcription factors in the nervous system

1 reference

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Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway

1 reference

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Functional interactions between estrogen and insulin-like growth factor-I in the regulation of alpha 1B-adrenoceptors and female reproductive function

1 reference

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6 September 2017

Cyclic changes in estradiol regulate synaptic plasticity through the MAP kinase pathway

1 reference

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6 September 2017

Transcriptional regulation by the phosphorylation-dependent factor CREB

1 reference

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6 September 2017

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

1 reference

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Multiple actions of steroid hormones--a focus on rapid, nongenomic effects

1 reference

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6 September 2017

Parkinson's disease and parkinsonism in a longitudinal study: two-fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging.

1 reference

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

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6 September 2017

Cellular survival: a play in three Akts

1 reference

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MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

1 reference

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6 September 2017

Novel mechanisms of estrogen action in the brain: new players in an old story.

1 reference

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6 September 2017

Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

6 September 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology

1 reference

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6 September 2017

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

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Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity

1 reference

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1 reference

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6 September 2017

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

6 September 2017

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

6 September 2017

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

6 September 2017

Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

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Molecular and cellular aspects of the insulin-like growth factor I receptor

1 reference

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6 September 2017

Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals

1 reference

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6 September 2017

Erythropoietin protects against 6-hydroxydopamine-induced dopaminergic cell death

1 reference

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14 September 2017

Investigative models for determining hormone therapy-induced outcomes in brain: evidence in support of a healthy cell bias of estrogen action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

14 September 2017

Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell-surface redistribution

1 reference

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The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17beta-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene

1 reference

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Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

29 September 2017

Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures

1 reference

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29 September 2017

Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease

1 reference

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1 reference

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Studies of the biogenic amine transporters. VIII: identification of a novel partial inhibitor of dopamine uptake and dopamine transporter binding

1 reference

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Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667142

27 June 2018

The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons.

1 reference

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Estrogen decreases corpus striatal neurotoxicity in response to 6-hydroxydopamine.

1 reference

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Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system.

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1 reference

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3 September 2018

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1 reference

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17-Beta estradiol rapidly enhances extracellular signal-regulated kinase 2 phosphorylation in the rat brain

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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3 September 2018

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1 reference

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1 reference

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1 reference

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1 reference

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3 September 2018

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1 reference

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1 reference

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3 September 2018

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic action of R-Ras and IGF-1 on Bcl-xL expression and caspase-3 inhibition in BaF3 cells: R-Ras and IGF-1 control distinct anti-apoptotic kinase pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/18278798

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-Like Growth Factor-I Protects Axotomized Rat Retinal Ganglion Cells from Secondary Death via PI3-K-Dependent Akt Phosphorylation and Inhibition of Caspase-3

1 reference

https://api.crossref.org/works/10.1002%2FDNEU.20609

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/DNEU.20609

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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