(Q37160327)

English

The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes

scientific article published on 18 June 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

type-1 diabetes

0 references

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2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

7

object named as

Csaba Szabo

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Jon G Mabley

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Kanneganti G K Murthy

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

William Williams

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Garry J Southan

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Andrew L Salzman

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

18 June 2008

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Endocrinology

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

198

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

581-589

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Imbalance in Th cell polarization and its relevance in type 1 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Adenosine receptor activation ameliorates type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Immunomodulatory and neuroprotective effects of inosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Reversal of established autoimmune diabetes by restoration of endogenous beta cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Mycophenolate mofetil and its mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

IMP and AMP deaminase in reperfusion injury down-regulates neutrophil recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

The NOD mouse model of type 1 diabetes: as good as it gets?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

6 September 2017

Inosine improves islet xenograft survival in immunocompetent diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

14 September 2017

Insulin-dependent diabetes mellitus as an autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

14 September 2017

Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

14 September 2017

Complete protection from low-dose streptozotocin-induced diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

14 September 2017

Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

29 September 2017

Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

29 September 2017

Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

29 September 2017

Inosine infusion prevents mortality in endotoxic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

27 June 2018

Down-regulation of multiple low dose streptozotocin-induced diabetes by mycophenolate mofetil.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

27 June 2018

An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

27 June 2018

Chemokines and T lymphocytes: more than an attraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

27 June 2018

Uric acid as radical scavenger and antioxidant in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

27 June 2018

Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

The combined inducible nitric oxide synthase inhibitor and free radical scavenger guanidinoethyldisulfide prevents multiple low-dose streptozotocin-induced diabetes in vivo and interleukin-1beta-induced suppression of islet insulin secretion in vitr

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Inhibition of autoimmune diabetes by mycophenolate mofetil is associated with down-regulation of TH1 cytokine-induced apoptosis in the target tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Inosine reduces inflammation and improves survival in a murine model of colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Inosine improves gut permeability and vascular reactivity in endotoxic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2669843

3 September 2018

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of inosine on reperfusion injury after heart transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remote reperfusion lung injury is associated with AMP deaminase 3 activation and attenuated by inosine monophosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Very-low-dose streptozotocin induces diabetes in insulin promoter-mB7-1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of cyclophosphamide induced diabetes development and pancreatic Th1 reactivity in NOD mice treated with the interleukin (IL)-12 antagonist IL-12(p40)2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inosiplex: a novel treatment in rheumatoid arthritis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 12 mRNA expression in islets correlates with beta-cell destruction in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chemokine binding protein M3 prevents diabetes induced by multiple low doses of streptozotocin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18562629

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1677/JOE-07-0511

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

release_y4xqzs7jwnc4tjxburqx2f5qpa

1 reference

https://api.fatcat.wiki/v0/release/y4xqzs7jwnc4tjxburqx2f5qpa

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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