(Q37163044)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

0 references

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Lipeng Bi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Wen-Xing Ding

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Winston Dunn

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Benjamin Roberts

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Tiangang Li

6

1 reference

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6 March 2020

publication date

31 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

6 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

54

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

2754-2762

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3770088/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

A ceramide-centric view of insulin resistance

6 September 2017

1 reference

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Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

The degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathways

6 September 2017

1 reference

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Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications

6 September 2017

1 reference

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Sphingolipids and cardiovascular diseases: lipoprotein metabolism, atherosclerosis and cardiomyopathy

6 September 2017

1 reference

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Human fatty liver disease: old questions and new insights

6 September 2017

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Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease

6 September 2017

1 reference

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Circulating sphingolipid biomarkers in models of type 1 diabetes

6 September 2017

1 reference

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Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

A functional role for the p62-ERK1 axis in the control of energy homeostasis and adipogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

The Vps10p-domain receptor family.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Mechanisms of Disease: hepatic steatosis in type 2 diabetes--pathogenesis and clinical relevance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Vascular function, insulin resistance and fatty acids

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Multiple CHD risk factors in type 2 diabetes: beyond hyperglycaemia

6 September 2017

1 reference

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The role of the LDL receptor in apolipoprotein B secretion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Acute effects of insulin in the control of VLDL production in humans. Implications for the insulin-resistant state

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Free fatty acid metabolic profile and biomarkers of isolated post-challenge diabetes and type 2 diabetes mellitus based on GC–MS and multivariate statistical analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770088

Free fatty acids (FFA) and endothelial dysfunction; role of increased oxidative stress and inflammation. --to: Steinberg et al. (2002) Vascular function, insulin resistance and fatty acids

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23904453

12 December 2020

inferred from PubMed ID database lookup

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23904453

12 December 2020

inferred from PubMed ID database lookup

Sortilin turnover is mediated by ubiquitination

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23904453

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1194/JLR.M039347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23904453%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

23904453

1 reference