(Q37163495)

English

Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets

scientific article published on 17 February 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ubiquitin-proteasome system

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Christophe Broca

object named as

Christophe Broca

4

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author name string

Safia Costes

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Brigitte Vandewalle

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Cécile Tourrel-Cuzin

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Nathalie Linck

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Gyslaine Bertrand

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Julie Kerr-Conte

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Bernard Portha

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

François Pattou

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Joel Bockaert

10

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Stéphane Dalle

11

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Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

17 February 2009

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Europe PubMed Central

PMC publication ID

18 August 2017

number of pages

11

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based on heuristic

inferred from page(s)

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Europe PubMed Central

PMC publication ID

18 August 2017

58

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1105-1115

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

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Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.

1 reference

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Sumoylation regulates the transcriptional activity of MafA in pancreatic beta cells

1 reference

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The GK rat beta-cell: a prototype for the diseased human beta-cell in type 2 diabetes?

1 reference

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Emerging role of SUMO in pancreatic beta-cells

1 reference

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Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats

1 reference

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Protein transduction technology offers a novel therapeutic approach for diabetes.

1 reference

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6 September 2017

Islet beta cell failure in type 2 diabetes

1 reference

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6 September 2017

Interventional strategies to prevent beta-cell apoptosis in islet transplantation.

1 reference

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6 September 2017

Role of ubiquitin-proteasome degradation pathway in biogenesis efficiency of {beta}-cell ATP-sensitive potassium channels

1 reference

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Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells

1 reference

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6 September 2017

Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt?

1 reference

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Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

1 reference

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6 September 2017

Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications

1 reference

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6 September 2017

Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection

1 reference

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Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia

1 reference

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

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6 September 2017

Proteasomes in apoptosis: villains or guardians?

1 reference

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6 September 2017

Phosphorylation-dependent targeting of cAMP response element binding protein to the ubiquitin/proteasome pathway in hypoxia

1 reference

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CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

1 reference

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6 September 2017

In vivo protein transduction: delivery of a biologically active protein into the mouse

1 reference

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6 September 2017

Substrate targeting in the ubiquitin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671045

6 September 2017

The ubiquitin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671045

6 September 2017

Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

1 reference

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6 September 2017

CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme

1 reference

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6 September 2017

ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671045

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Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion

1 reference

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14 September 2017

ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity

1 reference

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Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells.

1 reference

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Cooperative effects between protein kinase A and p44/p42 mitogen-activated protein kinase to promote cAMP-responsive element binding protein activation after beta cell stimulation by glucose and its alteration due to glucotoxicity.

1 reference

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Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells

1 reference

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Extracellularly regulated kinases 1/2 (p44/42 mitogen-activated protein kinases) phosphorylate synapsin I and regulate insulin secretion in the MIN6 beta-cell line and islets of Langerhans

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cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

1 reference

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Cytokine-mediated down-regulation of the transcription factor cAMP-response element-binding protein in pancreatic beta-cells

1 reference

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Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets.

1 reference

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The proteasome is required for rapid initiation of death receptor-induced apoptosis

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Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

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Protection of islets in culture by delivery of oxygen binding neuroglobin via protein transduction

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Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective po

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Altered bcl-2 and bax expression and intracellular Ca2+ signaling in apoptosis of pancreatic cells and the impairment of glucose-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19223597

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based on heuristic

inferred from PubMed ID database lookup

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19223597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a Role of the Ubiquitin-Proteasome Pathway in Pancreatic Islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/19223597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of preservation solution on human islet isolation outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19223597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB08-0926

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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