(Q37164665)

18 August 2017

1 reference

title

Molecular pharmacodynamics, clinical therapeutics, and pharmacokinetics of topiramate (English)

1 reference

18 August 2017

1 reference

1 reference

Richard P Shank

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

14 May 2020

Bruce E Maryanoff

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

14 May 2020

publication date

1 January 2008

1 reference

18482025

CNS Neuroscience & Therapeutics

18 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

14 May 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

14 May 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

14 May 2020

page(s)

120-142

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

Topiramate serum concentration-to-dose ratio: influence of age and concomitant antiepileptic drugs and monitoring implications

14 May 2020

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Topiramate inhibits trigeminovascular activation: an intravital microscopy study

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Topiramate inhibits cortical spreading depression in rat and cat: impact in migraine aura

21 January 2018

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Newer antiepileptic drugs and cognitive issues

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Pathogenesis and pharmacology of epilepsy in the lithium-pilocarpine model.

21 January 2018

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Topiramate reduces AMPA-induced Ca(2+) transients and inhibits GluR1 subunit phosphorylation in astrocytes from primary cultures

21 January 2018

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Effects of antiepileptic drugs on extracellular pH regulation in the hippocampal CA1 region in vivo

21 January 2018

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Topiramate: a new potential pharmacological treatment for obesity

21 January 2018

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Predictors of Weight Loss in Adults with Topiramate‐Treated Epilepsy

21 January 2018

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Painful posttraumatic trigeminal neuropathy: a case report of relief with topiramate

21 January 2018

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Oligohydrosis and hyperthermia: pilot study of a novel topiramate adverse effect.

21 January 2018

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Prospective open-label study of add-on and monotherapy topiramate in civilians with chronic nonhallucinatory posttraumatic stress disorder

21 January 2018

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Pharmacokinetic interactions of topiramate

21 January 2018

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The pharmacokinetics and interactions of new antiepileptic drugs: an overview

21 January 2018

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Evaluation of topiramate as an anti-hyperalgesic and neuroprotective agent in the peripheral nervous system

21 January 2018

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Novel anticonvulsants in the treatment of alcoholism

21 January 2018

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A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity

21 January 2018

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Topiramate attenuates withdrawal signs after chronic intermittent ethanol in rats

21 January 2018

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Antiepileptic drugs in migraine: from clinical aspects to cellular mechanisms

21 January 2018

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Role of topiramate for the treatment of painful diabetic peripheral neuropathy

21 January 2018

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Pharmacologic treatment of binge eating disorder

21 January 2018

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Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Effect of topiramate following recurrent and prolonged seizures during early development

21 January 2018

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Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: a case-series

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

A double-blind placebo-controlled trial of topiramate treatment for essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Palatability-dependent appetite and benzodiazepines: new directions from the pharmacology of GABA(A) receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Protein-kinase C-dependent phosphorylation inhibits the effect of the antiepileptic drug topiramate on the persistent fraction of sodium currents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Antiepileptic drugs in the prophylaxis of migraine, chronic headache forms and cluster headache: a review of their efficacy and tolerability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate for binge eating disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Transient hypohidrosis induced by topiramate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate reduces headache days in chronic migraine: a randomized, double-blind, placebo-controlled study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Single-dose pharmacokinetics and effect of food on the bioavailability of topiramate, a novel antiepileptic drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Effect of topiramate or carbamazepine on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in healthy obese and nonobese female subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Clinical activity of venlafaxine and topiramate against oxaliplatin-induced disabling permanent neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate as a neuroprotectant in a rat model of global ischemia-induced neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate monotherapy in the maintenance treatment of bipolar I disorder: effects on mood, weight and serum lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Gabapentin and vigabatrin increase GABA in the human neocortical slice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, and glutamine concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate for migraine prophylaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The combination of topiramate and diazepam is partially neuroprotective in the hippocampus but not antiepileptogenic in the lithium-pilocarpine model of temporal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The antiepileptic drug topiramate preserves metabolism-secretion coupling in insulin secreting cells chronically exposed to the fatty acid oleate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

A double-blind, placebo-controlled, crossover trial of topiramate in essential tremor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Amelioration of water maze performance deficits by topiramate applied during pilocarpine-induced status epilepticus is negatively dose-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Severe topiramate-associated hyperthermia resulting in persistent neurological dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Clinical pharmacology of topiramate: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Impact of topiramate on serum bicarbonate concentrations in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Low doses of topiramate are effective in essential tremor: a report of three cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Therapeutic doses of topiramate are not toxic to the developing rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Migraine--current understanding and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The influence of antiepileptic drugs on cognition: a comparison of levetiracetam with topiramate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Differential sensitivity of recombinant GABA(A) receptors expressed in Xenopus oocytes to modulation by topiramate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Beneficial biochemical outcomes of late-onset dietary restriction in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate and metabolic acidosis: a case series and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Experience with topiramate monotherapy in elderly patients with recent-onset epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Response of recurrent binge eating and weight gain to topiramate in patients with binge eating disorder after bariatric surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Comparison of obese men and women with binge eating disorder seeking weight management

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Two new actions of topiramate: inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate plus paroxetine in treatment-resistant obsessive-compulsive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Identification of arylsulfonamides as Aquaporin 4 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

New treatments of bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Therapeutic drug monitoring of the newer antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate-induced neuromodulation of cortico-mesolimbic dopamine function: a new vista for the treatment of comorbid alcohol and nicotine dependence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Uses of topiramate in the treatment of alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate for treating alcohol dependence: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Suicidality and antiepileptic drugs: is there a link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

A pilot trial of topiramate for the treatment of cocaine dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Multiple actions of the novel anticonvulsant drug topiramate in the rat subiculum in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate attenuates exaggerated acoustic startle in an animal model of PTSD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The effect of topiramate on GABA(B) receptor, vesicular GABA transporter and paired-pulse inhibition in the gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Painful diabetic peripheral neuropathy relieved with use of oral topiramate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Cognitive profile of topiramate as compared with lamotrigine in epilepsy patients on antiepileptic drug polytherapy: relationships to blood serum levels and comedication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate blocks perinatal hypoxia-induced seizures in rat pups

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

NBQX or topiramate treatment after perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate in children with west syndrome: a retrospective multicenter evaluation of 100 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The mechanism of neuroprotection by topiramate in an animal model of epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate monotherapy in the management of acute mania: results of four double-blind placebo-controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate inhibits the initiation of plateau potentials in CA1 neurons by depressing R-type calcium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate increases cerebral GABA in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Drug-induced acute angle closure glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Additive effects of leptin and topiramate in reducing fat deposition in lean and obese ob/ob mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Obsessive-compulsive beliefs and magical ideation in eating disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate modulates pH of hippocampal CA3 neurons by combined effects on carbonic anhydrase and Cl-/HCO3- exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Basic research in epilepsy and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Aquaporins and CFTR in ocular epithelial fluid transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate ameliorates hyperglycaemia and improves glucose-stimulated insulin release in ZDF rats and db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Isolation, culture, and characterization of human fetal trabecular meshwork cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Role of hepatic carbonic anhydrase in de novo lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate reduces the harm of excessive drinking: implications for public health and primary care

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate reduced sweat secretion and aquaporin-5 expression in sweat glands of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate protects against motor neuron degeneration in organotypic spinal cord cultures but not in G93A SOD1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Comparison of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-II by using topiramate as a structural platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Age-dependent effects of topiramate on the acquisition and the retention of rapid kindling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Open-label adjunctive topiramate in the treatment of bipolar disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Inhibition of alpha(1E) Ca(2+) channels by carbonic anhydrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate: efficacy and tolerability in children according to epilepsy syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The water channels, new druggable targets to combat cancer cell survival, invasiveness and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The role of anticonvulsant drugs in anxiety disorders: a critical review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate reduces neuronal injury after experimental status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Exocytosis mechanism as a new targeting site for mechanisms of action of antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Biphasic actions of topiramate on monoamine exocytosis associated with both soluble N-ethylmaleimide-sensitive factor attachment protein receptors and Ca(2+)-induced Ca(2+)-releasing systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate in essential tremor: a double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The suppression of primary palmar-plantar hyperhidrosis by topiramate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The clinical pharmacokinetics of the new antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Clinically relevant drug interactions with antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate and metabolic acidosis in infants and toddlers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate alters excitatory synaptic transmission in mouse hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate vs placebo in painful diabetic neuropathy: analgesic and metabolic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Rapid resolution of topiramate-induced angle-closure glaucoma with methylprednisolone and mannitol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Reversal of phrenic nerve palsy with topiramate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Influence of topiramate in the regulation of energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Neuroprotective properties of topiramate in the lithium-pilocarpine model of epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate hyperpolarizes and modulates the slow poststimulus AHP of rat olfactory cortical neurones in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Kidney Stones and the Ketogenic Diet: Risk Factors and Prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Ocular adverse effects associated with systemic medications : recognition and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate selectively attenuates nicotine-induced increases in monoamine release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Neuroprotective effects of topiramate after hypoxia-ischemia in newborn piglets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate prevents excitotoxic damage in the newborn rodent brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Plasma and whole blood pharmacokinetics of topiramate: the role of carbonic anhydrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Calcium channels modulate nociceptive transmission in the trigeminal nucleus of the cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Control of topiramate-induced paresthesias with supplemental potassium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Efficacy and safety of topiramate for the treatment of chronic migraine: a randomized, double-blind, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Subunit selectivity of topiramate modulation of heteromeric GABA(A) receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Effects of topiramate on kainate- and domoate-activated [14C]guanidinium ion flux through GluR6 channels in transfected BHK cells using Cytostar-T scintillating microplates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Distinct cognitive neurophysiologic profiles for lamotrigine and topiramate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate promotes neurite outgrowth and recovery of function after nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Emerging pharmacological strategies in the fight against cocaine addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Safety and efficacy of anticonvulsants in elderly patients with psychiatric disorders: oxcarbazepine, topiramate and gabapentin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

A comparison of topiramate and acetazolamide on seizure duration and paired-pulse inhibition in the dentate gyrus of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Treatment of experimental status epilepticus in immature rats: dissociation between anticonvulsant and antiepileptogenic effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Carbamazepine and topiramate modulation of transient and persistent sodium currents studied in HEK293 cells expressing the Na(v)1.3 alpha-subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Functional switching of GABAergic synapses by ryanodine receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Modelling intracellular H(+) ion diffusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate and metabolic acidosis in pediatric epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate in painful diabetic polyneuropathy: findings from three double-blind placebo-controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Efficacy and safety of topiramate in the treatment of obese subjects with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Spontaneous epileptiform activity mediated by GABA(A) receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABA(B) antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Efficacy and tolerability of topiramate in children younger than 2 years old.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate augmentation in treatment-resistant obsessive-compulsive disorder: a retrospective, open-label case series

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The role of glutamate and its receptors in migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate: as monotherapy in newly diagnosed epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Donepezil treatment of topiramate-related cognitive dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

A randomized double-blind placebo-controlled study of the long-term efficacy and safety of topiramate in the treatment of obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate treatment causes skeletal muscle insulin sensitization and increased Acrp30 secretion in high-fat-fed male Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Sulfamates and their therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Frequency-dependent inhibition of neuronal activity by topiramate in rat hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Neuroprotection by delayed administration of topiramate in a rat model of middle cerebral artery embolization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Effect of topiramate on body weight and body composition of osborne-mendel rats fed a high-fat diet: alterations in hormones, neuropeptide, and uncoupling-protein mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Effect of topiramate on cognitive function and activity level following neonatal seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Neurochemical phenotype of hypothalamic neurons showing Fos expression 23 h after intracranial AgRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

The Effects of Topiramate Adjunctive Treatment Added to Antidepressants in Patients with Resistant Obsessive-compulsive Disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2008.00041.X

Inhibition of transient and persistent Na+ current fractions by the new anticonvulsant topiramate

21 January 2018

1 reference

12 December 2020

Treatment of acute mania with topiramate

1 reference

12 December 2020

Topiramate depresses carbachol-induced plateau potentials in subicular bursting cells

1 reference

12 December 2020

Enhanced neuroprotection and reduced hemorrhagic incidence in focal cerebral ischemia of rat by low dose combination therapy of urokinase and topiramate

1 reference

12 December 2020

Protective effect of topiramate against hippocampal neuronal damage after global ischemia in the gerbils

1 reference

12 December 2020

An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanism of action

1 reference

12 December 2020

Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism

1 reference

12 December 2020

Effects of topiramate on sodium-dependent action-potential firing by mouse spinal cord neurons in cell culture

1 reference

12 December 2020

Concentration-effect studies with topiramate on selected enzymes and intermediates of the GABA shunt

1 reference

12 December 2020

Topiramate as an inhibitor of carbonic anhydrase isoenzymes

1 reference

12 December 2020

Topiramate blocks kainate-evoked cobalt influx into cultured neurons

1 reference

12 December 2020

Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate

1 reference

12 December 2020

Topiramate reduces energy and fat gains in lean (Fa/?) and obese (fa/fa) Zucker rats

1 reference

12 December 2020

A new form of feedback at the GABA(A) receptor

1 reference

12 December 2020

Topiramate in posttraumatic stress disorder: preliminary clinical observations.

1 reference

12 December 2020

Topiramate-induced metabolic acidosis: report of two cases

1 reference

12 December 2020

Behavioral analysis of anorexia produced by hindbrain injections of AMPA receptor antagonist NBQX in rats

1 reference

12 December 2020

Open-label topiramate as primary or adjunctive therapy in chronic civilian posttraumatic stress disorder: a preliminary report.

1 reference

12 December 2020

The effects of topiramate and sex hormones on energy balance of male and female rats

1 reference

12 December 2020

Facilitation of intracellular H(+) ion mobility by CO(2)/HCO(3)(-) in rabbit ventricular myocytes is regulated by carbonic anhydrase

1 reference

12 December 2020

Oral potassium citrate treatment for idiopathic hypocitruria in children with calcium urolithiasis

1 reference

12 December 2020

Topiramate treatment for SSRI-induced weight gain in anxiety disorders.

1 reference

12 December 2020

Interaction of calcineurin and type-A GABA receptor gamma 2 subunits produces long-term depression at CA1 inhibitory synapses

1 reference

12 December 2020

AMPA blockade may be the mechanism underlying the efficacy of topiramate in PTSD.

1 reference

12 December 2020

Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons

1 reference

12 December 2020

Mechanism of the anticonvulsant action of acetazoleamide, a carbonic anhydrase inhibitor

1 reference

12 December 2020

Treatment of bulimia nervosa with topiramate in a randomized, double-blind, placebo-controlled trial, part 1: improvement in binge and purge measures.

1 reference

12 December 2020

Topiramate modulation of kainate-induced calcium currents is inversely related to channel phosphorylation level.

1 reference

12 December 2020

Inhibitory effect of topiramate on Lewis lung carcinoma metastasis and its relation with AQP1 water channel

1 reference

12 December 2020

Neuroprotective effects of topiramate

1 reference

12 December 2020

Topiramate in the long-term treatment of binge-eating disorder associated with obesity

1 reference

12 December 2020

An open trial of topiramate in the treatment of generalized social phobia.

1 reference

12 December 2020

Pharmacotherapy for obesity

1 reference

12 December 2020

Dysfunctional fat cells, lipotoxicity and type 2 diabetes

1 reference

12 December 2020

[Topiramate and pregnancy. Neonate with bone anomalies]

1 reference

12 December 2020

Symptomatic and asymptomatic hypohidrosis in children under topiramate treatment.

1 reference

12 December 2020

Topiramate stimulates glucose transport through AMP-activated protein kinase-mediated pathway in L6 skeletal muscle cells

1 reference

12 December 2020

Hypohidrosis during topiramate treatment: a rare and reversible side effect

1 reference

12 December 2020

New insights into migraine pathophysiology

1 reference

12 December 2020

Efficacy and safety of topiramate in combination with metformin in the treatment of obese subjects with type 2 diabetes: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Topiramate may induce obsessive-compulsive disorder

1 reference

12 December 2020

Topiramate induces type 3 renal tubular acidosis by inhibiting renal carbonic anhydrase

1 reference

12 December 2020

Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements

1 reference

12 December 2020

Topiramate-induced bilateral angle-closure glaucoma

1 reference

12 December 2020

The impact of migraine on daily activities: effect of topiramate compared with placebo

1 reference

12 December 2020

Facial hyperhidrosis-induced social fear alleviated with topiramate

1 reference

12 December 2020

[Topiramate for the treatment of post traumatic stress disorder. A case study]

1 reference

12 December 2020

Biochemical and stone-risk profiles with topiramate treatment

1 reference

12 December 2020

Examination of two independent kinetic assays for determining the inhibition of carbonic anhydrases I and II: structure-activity comparison of sulfamates and sulfamides

1 reference

12 December 2020

Prospective study of first-choice topiramate therapy in newly diagnosed infantile spasms

1 reference

12 December 2020

Adjunctive topiramate therapy in patients receiving a mood stabilizer for bipolar I disorder: a randomized, placebo-controlled trial

1 reference

12 December 2020

Topiramate for the treatment of binge eating disorder associated with obesity: a placebo-controlled study

1 reference

12 December 2020

Bilateral angle closure glaucoma induced by sulphonamide-derived medications

1 reference

12 December 2020

Efficacy and safety of topiramate monotherapy in civilian posttraumatic stress disorder: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients

1 reference

12 December 2020

Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam

1 reference

12 December 2020

Topiramate in the treatment of obese subjects with drug-naive type 2 diabetes

1 reference

12 December 2020

[Experimental study on the possibility of brain damage induced by chronic treatment with phenobarbital, clonazepam, valproic acid and topiramate in immature rats]

1 reference

12 December 2020

Use of the newer antiepileptic drugs in pediatric epilepsies

1 reference

12 December 2020

Truncated AUCs in the assessment of the bioequivalence of topiramate, a long half-life drug

1 reference

12 December 2020

Topiramate monotherapy in newly diagnosed epilepsy in children and adolescents

1 reference

12 December 2020

[Rational combination therapy in epilepsy. II. Clinical and pharmacological aspects]

1 reference

12 December 2020

Aquaporins as Targets for Drug Discovery

1 reference

12 December 2020

Use of topiramate for glossodynia

1 reference

12 December 2020

Low-dose topiramate (topamax) in the treatment of essential tremor

1 reference

12 December 2020

[Bilateral angle-closure glaucoma induced by trimetoprim and sulfamethoxazole combination: case report]

1 reference

12 December 2020

Topiramate: a review of its use in the treatment of epilepsy

1 reference

12 December 2020

A randomized, double-blind, placebo-controlled trial of augmentation topiramate for chronic combat-related posttraumatic stress disorder

1 reference

12 December 2020

Carbonic anhydrase inhibition. Insight into the characteristics of zonisamide, topiramate, and the sulfamide cognate of topiramate

1 reference

12 December 2020

Sugar sulfamates for seizure control: discovery and development of topiramate, a structurally unique antiepileptic drug

1 reference

12 December 2020

Mechanisms of tolerance to the anticonvulsant effects of acetazolamide in mice: relation to the activity and amount of carbonic anhydrase in brain

1 reference

12 December 2020

Carbonic anhydrase: chemistry, physiology, and inhibition

1 reference

12 December 2020

Bilateral acute angle-closure glaucoma associated with drug sensitivity to hydrochlorothiazide

1 reference

12 December 2020

Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors

1 reference

12 December 2020

Heterogeneity of carbonic anhydrase and 68 kDa neurofilament in nerve roots analyzed by two-dimensional electrophoresis

1 reference

12 December 2020

Topiramate: preclinical evaluation of structurally novel anticonvulsant.

1 reference

12 December 2020

Inhibition by topiramate of seizures in spontaneously epileptic rats and DBA/2 mice

1 reference

12 December 2020

Steady-state pharmacokinetics of topiramate and carbamazepine in patients with epilepsy during monotherapy and concomitant therapy

1 reference

12 December 2020

Topiramate reduces abnormally high extracellular levels of glutamate and aspartate in the hippocampus of spontaneously epileptic rats (SER)

1 reference

12 December 2020

Comparison of the steady-state pharmacokinetics of topiramate and valproate in patients with epilepsy during monotherapy and concomitant therapy

1 reference

12 December 2020

10.1111/J.1527-3458.2008.00041.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494007&resulttype=core&format=json

14 May 2020

18482025

1 reference