(Q35827491)

10 August 2017

1 reference

title

Clinically relevant drug interactions with antiepileptic drugs (English)

1 reference

10 August 2017

1

Emilio Perucca

1 reference

PMC publication ID

1885026

10 August 2017

language of work or name

English

0 references

publication date

1 March 2006

1 reference

British Journal of Clinical Pharmacology

10 August 2017

1 reference

10 August 2017

61

1 reference

10 August 2017

3

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10 August 2017

246-255

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Pharmacokinetic interactions of topiramate

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Anticonvulsant and antiretroviral interactions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Antiepileptic-induced resistance to neuromuscular blockers: mechanisms and clinical significance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Epilepsy and comorbidity: infections and antimicrobials usage in relation to epilepsy management

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

The pharmacokinetics of oxcarbazepine and its active metabolite 10-hydroxy-carbazepine in healthy subjects and in epileptic patients treated with phenobarbitone or valproic acid

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Interactions between antiepileptic and chemotherapeutic drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Drug treatment of epilepsy in elderly people: focus on valproic Acid

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Drugs as P-glycoprotein substrates, inhibitors, and inducers

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

The importance of drug interactions in epilepsy therapy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Interactions between antiepileptic drugs and hormonal contraception

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Changes in plasma protein binding have little clinical relevance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Clinical significance of pharmacokinetic interactions between antiepileptic and psychotropic drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Implications of cytochrome P450 interactions when prescribing medication for hypertension

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Clinical pharmacology and therapeutic use of the new antiepileptic drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

New antiepileptic drugs: review on drug interactions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Harnessing the clinical potential of antiepileptic drug therapy: dosage optimisation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Therapeutic dilemma: the use of anticonvulsants in HIV-positive individuals

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Metabolism-based drug interactions involving oral azole antifungals in humans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Population analysis of the pharmacokinetics of tiagabine in patients with epilepsy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

A mechanistic approach to antiepileptic drug interactions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Carbamazepine toxicity with lamotrigine: pharmacokinetic or pharmacodynamic interaction?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

In vitro approaches to predicting drug interactions in vivo.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

A review of enzyme induction of warfarin metabolism with recommendations for patient management

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Status epilepticus associated with the combination of valproic acid and clomipramine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Reduced plasma nisoldipine concentrations in phenytoin-treated patients with epilepsy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Clinically important drug interactions with anticoagulants. An update

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Antiepileptic medication and oral contraceptive interactions: a national survey of neurologists and obstetricians.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Oxcarbazepine: pharmacokinetic interactions and their clinical relevance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Macrolide antibacterials. Drug interactions of clinical significance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Influence of phenytoin and phenobarbital on the disposition of a single oral dose of clonazepam

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Effect of valproate on free plasma phenytoin concentrations

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Clinical implications of hepatic microsomal enzyme induction by antiepileptic drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

The interaction of phenytoin and carbamazepine with combined oral contraceptive steroids

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Differential effects of valproic acid and enzyme-inducing anticonvulsants on nimodipine pharmacokinetics in epileptic patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Sodium valproate acutely inhibits lamotrigine metabolism

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Interactions between clobazam and standard antiepileptic drugs in patients with epilepsy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Disposition of sodium valproate in epileptic patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Serum valproate levels with oral contraceptive use.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

The complexity of achieving anticoagulation control in the face of warfarin-phenytoin interaction: an Asian case report.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Pharmacokinetic and metabolic investigation of topiramate disposition in healthy subjects in the absence and in the presence of enzyme induction by carbamazepine

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Oral contraceptives reduce lamotrigine plasma levels

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Effect of topiramate or carbamazepine on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in healthy obese and nonobese female subjects

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Observational series on women using the contraceptive Mirena concurrently with anti-epileptic and other enzyme-inducing drugs

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Factors contributing to carbamazepine-macrolide interactions

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Lamotrigine plasma levels reduced by oral contraceptives

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Lack of an effect of valproate concentration on lamotrigine pharmacokinetics in developmentally disabled patients with epilepsy.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Carbamazepine--indinavir interaction causes antiretroviral therapy failure.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Gender difference in management of epilepsy-what women are hearing.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885026

Effect of topiramate on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in patients with epilepsy

24 September 2018

1 reference

12 December 2020

The influence of dosage, age, and comedication on steady state plasma lamotrigine concentrations in epileptic children: a prospective study with preliminary assessment of correlations with clinical response

1 reference

12 December 2020

Lowering of plasma valproic acid concentrations during concomitant therapy with meropenem and amikacin

1 reference

12 December 2020

Lamotrigine serum concentration-to-dose ratio: influence of age and concomitant antiepileptic drugs and dosage implications

1 reference

12 December 2020

Clinical Observations of Possible Barbiturate Interference With Anticoagulation

1 reference

12 December 2020

Influence of phenobarbital and diphenylhydantoin on plasma carbamazepine levels in patients with epilepsy

1 reference

12 December 2020

Interaction between phenytoin and valproic acid: plasma protein binding and metabolic effects

1 reference

12 December 2020

Mechanism of valproate-phenobarbital interaction in epileptic patients

1 reference

12 December 2020

Interference of oral phenytoin absorption by continuous nasogastric feedings

1 reference

12 December 2020

Valproate-ethosuximide combination therapy for refractory absence seizures

1 reference

12 December 2020

Phenytoin and nasogastric feedings

1 reference

12 December 2020

Oxcarbazepine placebo-controlled, dose-ranging trial in refractory partial epilepsy

1 reference

12 December 2020

Serum concentrations of valproic acid: influence of dose and comedication

1 reference

12 December 2020

Acute effects of lamotrigine (BW430C) in persons with epilepsy

1 reference

12 December 2020

Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy

1 reference

12 December 2020

Sodium valproate and valpromide: differential interactions with carbamazepine in epileptic patients

1 reference

12 December 2020

Discontinuation of phenytoin and carbamazepine in patients receiving felbamate

1 reference

12 December 2020

Phenytoin and carbamazepine decreased oral bioavailability of praziquantel

1 reference

12 December 2020

Changes in unbound and total valproic acid concentrations after replacement of carbamazepine with oxcarbazepine

1 reference

12 December 2020

Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin

1 reference

12 December 2020

10.1111/J.1365-2125.2005.02529.X

Identifiers

DOI

1 reference

10 August 2017

1 reference

PMC publication ID

1885026

10 August 2017

PubMed publication ID

16487217

1 reference

PMC publication ID

1885026