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Activation of ATR and related PIKKs
scientific article published on 30 September 2008
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
title
Activation of ATR and related PIKKs
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
author name string
Daniel A Mordes
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
David Cortez
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
publication date
30 September 2008
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stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
number of pages
4
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based on heuristic
inferred from page(s)
published in
Cell Cycle
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
volume
7
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
page(s)
2809-2812
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stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
issue
18
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
cites work
ATR: an essential regulator of genome integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
The DNA damage response: ten years after
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Function of a conserved checkpoint recruitment domain in ATRIP proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
TopBP1 activates the ATR-ATRIP complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Oncogenic PI3K deregulates transcription and translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Identification and functional analysis of TopBP1 and its homologs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Rheb binds and regulates the mTOR kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Regulation of DNA replication by ATR: signaling in response to DNA intermediates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
ATR and ATRIP: partners in checkpoint signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
The DNA-dependent protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Enhanced phosphorylation of p53 by ATM in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
6 September 2017
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
14 September 2017
The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
14 September 2017
ATRIP oligomerization is required for ATR-dependent checkpoint signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
27 June 2018
Aven-dependent activation of ATM following DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
3 September 2018
How ATR turns on: TopBP1 goes on ATRIP with ATR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
3 September 2018
The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
3 September 2018
Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
3 September 2018
The ATRs, ATMs, and TORs are giant HEAT repeat proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672405
retrieved
3 September 2018
Identifiers
DOI
10.4161/CC.7.18.6689
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
PMCID
2672405
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
PubMed ID
18769153
1 reference
stated in
Europe PubMed Central
PMCID
2672405
retrieved
18 August 2017
ResearchGate publication ID
23235769
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