(Q37168156)

18 August 2017

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title

Protein-glycan interactions in the control of innate and adaptive immune responses (English)

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18 August 2017

1

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18 August 2017

Gabriel A Rabinovich

2

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PubMed ID

18490910

18 August 2017

language of work or name

English

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publication date

1 June 2008

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18 August 2017

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18 August 2017

9

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18 August 2017

593-601

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18 August 2017

6

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Glycosylation in cellular mechanisms of health and disease

18 August 2017

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7 January 2021

Introduction to galectins

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7 January 2021

Siglecs and their roles in the immune system

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7 January 2021

Myeloid C-type lectins in innate immunity

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7 January 2021

The C-type lectin superfamily in the immune system

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7 January 2021

Oligosaccharide specificity of galectins: a search by frontal affinity chromatography.

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7 January 2021

Functions of cell surface galectin-glycoprotein lattices

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7 January 2021

Galectins as modulators of tumour progression

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7 January 2021

Visualization of galectin-3 oligomerization on the surface of neutrophils and endothelial cells using fluorescence resonance energy transfer

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7 January 2021

The C-type lectin-like domain superfamily

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7 January 2021

C-type lectin receptors on dendritic cells and Langerhans cells

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7 January 2021

Cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cells

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7 January 2021

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

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7 January 2021

Multiple Modes of Binding Enhance the Affinity of DC-SIGN for High Mannose N-Linked Glycans Found on Viral Glycoproteins

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7 January 2021

Sweet preferences of MGL: carbohydrate specificity and function

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7 January 2021

Dectin-1: a signalling non-TLR pattern-recognition receptor

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7 January 2021

Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins

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7 January 2021

Paradigms for glycan-binding receptors in cell adhesion.

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7 January 2021

DC-SIGN: escape mechanism for pathogens

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7 January 2021

Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein.

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7 January 2021

Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact.

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7 January 2021

Toll-like receptor signaling pathways

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7 January 2021

In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

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7 January 2021

Self- and nonself-recognition by C-type lectins on dendritic cells

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7 January 2021

DC-SIGN mediates binding of dendritic cells to authentic pseudo-LewisY glycolipids of Schistosoma mansoni cercariae, the first parasite-specific ligand of DC-SIGN.

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7 January 2021

C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB

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7 January 2021

Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication

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7 January 2021

Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production

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7 January 2021

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

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7 January 2021

Helicobacter pylori phase variation, immune modulation and gastric autoimmunity

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7 January 2021

Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation

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7 January 2021

Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells

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7 January 2021

Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

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7 January 2021

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

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7 January 2021

Langerin is a natural barrier to HIV-1 transmission by Langerhans cells

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7 January 2021

Human macrophage C-type lectin specific for galactose and N-acetylgalactosamine promotes filovirus entry

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7 January 2021

Siglecs in innate immunity

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7 January 2021

Sampling and signaling in plasmacytoid dendritic cells: the potential roles of Siglec-H.

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7 January 2021

Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity

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7 January 2021

Specific recognition of Leishmania major poly-beta-galactosyl epitopes by galectin-9: possible implication of galectin-9 in interaction between L. major and host cells.

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7 January 2021

LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition

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7 January 2021

Galectin-3 interacts with naive and primed neutrophils, inducing innate immune responses

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7 January 2021

Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression

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7 January 2021

Evidence of a role for galectin-1 in acute inflammation

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7 January 2021

A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation.

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7 January 2021

Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells

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7 January 2021

Galectin-9 induces maturation of human monocyte-derived dendritic cells

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7 January 2021

Galectin-1-matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix.

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7 January 2021

Regulation of alternative macrophage activation by galectin-3.

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7 January 2021

Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophages

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7 January 2021

Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis.

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7 January 2021

DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2.

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7 January 2021

Close encounters of neutrophils and DCs

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7 January 2021

Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45.

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7 January 2021

Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death

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7 January 2021

Galectin-2 induces apoptosis of lamina propria T lymphocytes and ameliorates acute and chronic experimental colitis in mice

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7 January 2021

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

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7 January 2021

The ST6Gal I sialyltransferase selectively modifies N-glycans on CD45 to negatively regulate galectin-1-induced CD45 clustering, phosphatase modulation, and T cell death

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7 January 2021

Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens

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7 January 2021

Clustering of pre-B cell integrins induces galectin-1-dependent pre-B cell receptor relocalization and activation

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7 January 2021

Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling.

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7 January 2021

Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking

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7 January 2021

ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling

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7 January 2021

A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP

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7 January 2021

Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population

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7 January 2021

Sweet spots in functional glycomics

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7 January 2021

Carbohydrate recognition systems in autoimmunity.

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7 January 2021

Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- and T regulatory-mediated anti-inflammatory responses.

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7 January 2021

Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice.

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7 January 2021

Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

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7 January 2021

Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells

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7 January 2021

Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation.

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7 January 2021

Strongly enhanced IL-10 production using stable galectin-1 homodimers

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7 January 2021

A pivotal role for galectin-1 in fetomaternal tolerance

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7 January 2021

The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphoma

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7 January 2021

Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells.

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7 January 2021

Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function

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7 January 2021

Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation

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7 January 2021

Galectin-1 induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transduction

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7 January 2021

Soluble mannosylated myelin peptide inhibits the encephalitogenicity of autoreactive T cells during experimental autoimmune encephalomyelitis

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7 January 2021

Mannosylated PLP(139-151) induces peptide-specific tolerance to experimental autoimmune encephalomyelitis

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7 January 2021

A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists

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7 January 2021

Glycosylation defining cancer malignancy: new wine in an old bottle

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7 January 2021

Glycans in cancer and inflammation--potential for therapeutics and diagnostics

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7 January 2021

Recognition of tumor glycans by antigen-presenting cells

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7 January 2021

The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma.

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7 January 2021

Introduction of Sd(a) carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis

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7 January 2021

Loss of disialyl Lewis(a), the ligand for lymphocyte inhibitory receptor sialic acid-binding immunoglobulin-like lectin-7 (Siglec-7) associated with increased sialyl Lewis(a) expression on human colon cancers.

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7 January 2021

Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

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7 January 2021

Cutting edge: langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo

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7 January 2021

Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege.

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7 January 2021

O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1.

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7 January 2021

Sweet 'n' sour: the impact of differential glycosylation on T cell responses

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7 January 2021

Activation of murine CD4+ and CD8+ T lymphocytes leads to dramatic remodeling of N-linked glycans

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7 January 2021

N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells

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7 January 2021

Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins

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7 January 2021

Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.

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7 January 2021

Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis

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7 January 2021

Polylactosamine on glycoproteins influences basal levels of lymphocyte and macrophage activation.

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7 January 2021

Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis

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7 January 2021

Structural and mechanistic features of protein O glycosylation linked to CD8+ T-cell apoptosis

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7 January 2021

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

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7 January 2021

The impact of glycosylation on the biological function and structure of human immunoglobulins.

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7 January 2021

Protein glycosylation: chaperone mutation in Tn syndrome

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7 January 2021

Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans

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7 January 2021

Oligosaccharide microarrays to decipher the glyco code

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7 January 2021

Identifiers

DOI

10.1038/NI.F.203

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18 August 2017

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PubMed ID

18490910