(Q37171158)

English

6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo

scientific article published on March 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

0 references

1 reference

based on heuristic

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author name string

Hongxia Wang

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Yinsheng Wang

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

1 March 2009

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

48

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

2290-2299

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

In vitro replication and thermodynamic studies of methylation and oxidation modifications of 6-thioguanine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Genomic DNA methylation: the mark and its mediators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Azathioprine and UVA light generate mutagenic oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Worms gang up on bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

DNA methylation in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

The DNA methyltransferases of mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Human RNase H-mediated RNA cleavage from DNA-RNA duplexes is inhibited by 6-deoxythioguanosine incorporation into DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Identification and characterization of a family of mammalian methyl-CpG binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

Free radical adducts induce alterations in DNA cytosine methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

The purine path to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

6 September 2017

The effect of thiopurine drugs on DNA methylation in relation to TPMT expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

14 September 2017

Mutagenic and cytotoxic properties of 6-thioguanine, S6-methylthioguanine, and guanine-S6-sulfonic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

14 September 2017

Novel DNA lesions generated by the interaction between therapeutic thiopurines and UVA light

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

14 September 2017

Peripheral blood mononuclear cell DNA 6-thioguanine metabolite levels correlate with decreased interferon-gamma production in patients with Crohn's disease on AZA therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

14 September 2017

In vitro methylation of DNA with Hpa II methylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

14 September 2017

Quantitation of 6-thioguanine residues in peripheral blood leukocyte DNA obtained from patients receiving 6-mercaptopurine-based maintenance therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

28 September 2017

Cellular differentiation, cytidine analogs and DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

27 June 2018

Recognition of unusual DNA structures by human DNA (cytosine-5)methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

27 June 2018

Consequences of 6-thioguanine incorporation into DNA on polymerase, ligase, and endonuclease reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

27 June 2018

Analysis of Oligonucleotides by HPLC-Electrospray Ionization Mass Spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

3 September 2018

Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673989

3 September 2018

The stereochemistry of benzo[a]pyrene-2'-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioguanine substitution alters DNA cleavage mediated by topoisomerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of DNA methylation in malignant MOLT F4 lymphoblasts by 6-mercaptopurine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of oligonucleotides containing 6-O-methylguanine with human DNA (cytosine-5-)-methyltransferase [published erratumm appears in Biochemistry 1992 Aug 4;31(30):7008]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic mechanism of 6-thioguanine: hMutSalpha, the human mismatch binding heterodimer, binds to DNA containing S6-methylthioguanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tandem Mass Spectrometry of Small, Multiply Charged Oligonucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fundamental role of epigenetic events in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19236003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI801467Z

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

0 references

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