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Direct detection of alpha synuclein oligomers in vivo
scientific article published on 09 May 2013
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Europe PubMed Central
PMC publication ID
3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
title
Direct detection of alpha synuclein oligomers in vivo
(English)
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
main subject
Synuclein
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author
Darius Ebrahimi-Fakhari
series ordinal
6
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
Nikolaus R McFarland
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7
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Europe PubMed Central
PMC publication ID
3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
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Hemi Dimant
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1
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PMC publication ID
3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
Suneil K Kalia
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2
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3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
Lorraine V Kalia
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3
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PMC publication ID
3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Liya N Zhu
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4
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PMC publication ID
3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Laura Kibuuka
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5
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PMC publication ID
3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
Zhanyun Fan
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8
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PMC publication ID
3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Pamela J McLean
series ordinal
10
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
Bradley T Hyman
series ordinal
9
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
publication date
9 May 2013
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3776213
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
published in
Acta Neuropathologica Communications
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
1
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
6
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
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Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies
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Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).
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In vivo demonstration that alpha-synuclein oligomers are toxic
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6 September 2017
Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.
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6 September 2017
Expression of human A53T alpha-synuclein in the rat substantia nigra using a novel AAV1/2 vector produces a rapidly evolving pathology with protein aggregation, dystrophic neurite architecture and nigrostriatal degeneration with potential to model t
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Heat‐shock protein 70 modulates toxic extracellular α‐synuclein oligomers and rescues trans‐synaptic toxicity
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In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility
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Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.
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Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies
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6 September 2017
Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity
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Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy.
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6 September 2017
Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody
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6 September 2017
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6 September 2017
Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease
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6 September 2017
Imaging amyloid-beta deposits in vivo
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PubMed Central
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6 September 2017
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy
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6 September 2017
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6 September 2017
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6 September 2017
Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
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6 September 2017
CHIP targets toxic alpha-Synuclein oligomers for degradation
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14 September 2017
Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease
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14 September 2017
Alpha-synuclein S129 phosphorylation mutants do not alter nigrostriatal toxicity in a rat model of Parkinson disease
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26 June 2018
Molecular imaging of drug-modulated protein-protein interactions in living subjects
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26 June 2018
Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity
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26 June 2018
Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.
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3 September 2018
In vivo imaging of amyloid-beta deposits in mouse brain with multiphoton microscopy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3776213
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3 September 2018
Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3776213
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3 September 2018
Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3776213
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3 September 2018
6-hydroxy-dopamine induced degeneration of central monoamine neurons
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3776213
retrieved
3 September 2018
Identifiers
DOI
10.1186/2051-5960-1-6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Dimensions Publication ID
1044189504
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PMC publication ID
3776213
1 reference
stated in
Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
24252244
1 reference
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Europe PubMed Central
PMC publication ID
3776213
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252244%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
ResearchGate publication ID
258765605
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