(Q37181708)

18 August 2017

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title

Gene-environment interactions for complex traits: definitions, methodological requirements and challenges (English)

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18 August 2017

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2

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18 August 2017

5

Jenny Chang-Claude

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author name string

Astrid Dempfle

1

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18 August 2017

Rebecca Hein

3

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18 August 2017

Lars Beckmann

4

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18 August 2017

Helmut Schäfer

6

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18 August 2017

4 June 2008

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European Journal of Human Genetics

18 August 2017

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18 August 2017

16

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18 August 2017

1164-1172

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18 August 2017

10

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https://scigraph.springernature.com/pub.10.1038/ejhg.2008.106

18 August 2017

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Nutrigenomics and nutrigenetics

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Gene-environment interaction and aetiology of cancer: what does it mean and how can we measure it?

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Pharmacogenetic testing for drug metabolizing enzymes: is it happening in practice?

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

The genetics of sun sensitivity in humans

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Where the rubber meets the road in pharmacogenetics: assessment of gene-environment interactions.

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Replication validity of genetic association studies

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Sick individuals and sick populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Balancing life-style and genomics research for disease prevention

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Pharmacogenetics and drug development: the path to safer and more effective drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Pharmacogenetics goes genomic

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Evolving methods in genetic epidemiology. III. Gene-environment interaction in epidemiologic research

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

An epidemiologic approach to gene-environment interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Effect modification and the limits of biological inference from epidemiologic data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Epidemiological methods for studying genes and environmental factors in complex diseases

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Testing linkage and gene x environment interaction: comparison of different affected sib-pair methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Gene-environment interactions in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Study of genes and environmental factors in complex diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Nontraditional epidemiologic approaches in the analysis of gene-environment interaction: case-control studies with no controls!

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Potential misinterpretation of the case-only study to assess gene-environment interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Further development of the case-only design for assessing gene-environment interaction: evaluation of and adjustment for bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Differential misclassification and the assessment of gene-environment interactions in case-control studies.

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

A self-fulfilling prophecy: are we underestimating the role of the environment in gene-environment interaction research?

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Designing and analysing case-control studies to exploit independence of genotype and exposure

21 January 2018

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https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Genetics and genomics of infectious disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Iatrogenic Creutzfeldt-Jakob disease: an example of the interplay between ancient genes and modern medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Statistical design and analysis of pharmacogenetic trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Sample size requirements for indirect association studies of gene-environment interactions (G x E).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

The multiethnic cohort study: exploring genes, lifestyle and cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Sample size determination for studies of gene-environment interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Power and sample size calculations for case-control studies of gene-environment interactions with a polytomous exposure variable.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Using multiple drug exposure levels to optimize power in pharmacogenetic trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Trick or treat: the effect of placebo on the power of pharmacogenetic association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

The study of candidate genes in drug trials: sample size considerations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Power and sample size calculations in case-control studies of gene-environment interactions: comments on different approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

Sample size requirements for matched case-control studies of gene-environment interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Prospective dosing of warfarin based on cytochrome P-450 2C9 genotype.

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

The role of interacting determinants in the localization of genes

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Exploiting gene-environment interaction to detect genetic associations

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Case-parents design for gene-environment interaction

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Study of genes and environmental factors in complex diseases

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Study of genes and environmental factors in complex diseases

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Study of genes and environmental factors in complex diseases

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Genetic dissection methods: designs used for tests of gene-environment interaction

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Exploiting gene-environment independence in family-based case-control studies: increased power for detecting associations, interactions and joint effects

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Genetic epidemiology of infectious diseases in humans: design of population-based studies

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Genetic susceptibility to infectious diseases

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Testing drug response in the presence of genetic information: sampling issues for clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Regression to the truth: replication of association in pharmacogenetic studies

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2008.106

7 January 2021

Identifiers

DOI

10.1038/EJHG.2008.106

1 reference

18 August 2017

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