(Q37182767)

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A fusion protein between streptavidin and the endogenous TLR4 ligand EDA targets biotinylated antigens to dendritic cells and induces T cell responses in vivo.

scientific article published on 05 September 2013

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093105%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

A fusion protein between streptavidin and the endogenous TLR4 ligand EDA targets biotinylated antigens to dendritic cells and induces T cell responses in vivo (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093105%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

toll-like receptor

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inferred from title

11

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26 February 2020

12

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26 February 2020

Juan José Lasarte

13

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26 February 2020

Lorea Villanueva

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Lorea Villanueva

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26 February 2020

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Noelia Casares

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26 February 2020

Francisco Borrás-Cuesta

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Francisco Borrás-Cuesta

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26 February 2020

Francesc Rudilla

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Francesc Rudilla

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26 February 2020

Laura Arribillaga

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Laura Arribillaga

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26 February 2020

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Maika Durantez

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26 February 2020

9

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Marta Gorraiz

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26 February 2020

author name string

Teresa Lozano

3

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26 February 2020

Federico Rehberger

5

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26 February 2020

Marta Martinez

8

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26 February 2020

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publication date

5 September 2013

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26 February 2020

BioMed Research International

1 reference

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26 February 2020

2013

1 reference

Europe PubMed Central

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26 February 2020

864720

1 reference

Europe PubMed Central

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26 February 2020

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

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April 2022 Public Data File from Crossref

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A monovalent streptavidin with a single femtomolar biotin binding site

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TLR signalling and the function of dendritic cells

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

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6 September 2017

Immunization against hepatitis C virus with a fusion protein containing the extra domain A from fibronectin and the hepatitis C virus NS3 protein

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14 September 2017

In vivo targeting of antigens to human dendritic cells through DC-SIGN elicits stimulatory immune responses and inhibits tumor growth in grafted mouse models

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Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells

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Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity

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Dendritic cell survival and maturation are regulated by different signaling pathways.

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Avidin and streptavidin

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Identifiers

10.1155/2013/864720

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093105%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24093105%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

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Europe PubMed Central

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26 February 2020

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