(Q37183109)

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Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

scientific article published on 23 April 2013

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Europe PubMed Central

PMC publication ID

18 August 2017

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Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment (English)

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18 August 2017

mild cognitive impairment

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Andrew J. Saykin

37

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18 August 2017

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L Shen

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Simon Lovestone

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S Lovestone

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Patrizia Mecocci

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P Mecocci

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Alzheimer's Disease Neuroimaging Initiative

38

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Alzheimer's Disease Neuroimaging Initiative (ADNI)

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18 August 2017

Hilkka Soininen

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H Soininen

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Ronald C. Petersen

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R C Petersen

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C R Jack

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P S Aisen

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Lindsay A. Farrer

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AddNeuroMed Consortium

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AddNeuroMed Consortium

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Indiana Memory and Aging Study

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Indiana Memory and Aging Study

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Multi-Institutional Research on Alzheimer Genetic Epidemiology (MIRAGE) Study

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Multi-Institutional Research on Alzheimer Genetic Epidemiology (MIRAGE) Study

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Martin R. Farlow

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M R Farlow

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K Nho

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J J Corneveaux

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S Kim

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H Lin

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S L Risacher

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S Swaminathan

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V K Ramanan

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Y Liu

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T Foroud

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M H Inlow

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A L Siniard

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R A Reiman

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R C Green

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M W Weiner

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C T Baldwin

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K Lunetta

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S J Furney

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A Simmons

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B Vellas

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M Tsolaki

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I Kloszewska

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B C McDonald

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B Ghetti

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M J Huentelman

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23 April 2013

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Molecular Psychiatry

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18 August 2017

18

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7

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18 August 2017

781-787

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18 August 2017

Poly(ADP-ribose) polymerase-1 in amyloid beta toxicity and Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk

1 reference

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6 September 2017

Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease

1 reference

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The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.

1 reference

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6 September 2017

Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data

1 reference

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6 September 2017

Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death

1 reference

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6 September 2017

CARMA3: A novel scaffold protein in regulation of NF-κB activation and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss

1 reference

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6 September 2017

A framework for variation discovery and genotyping using next-generation DNA sequencing data

1 reference

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6 September 2017

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Longitudinal MRI atrophy biomarkers: relationship to conversion in the ADNI cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

The CARMA3-Bcl10-MALT1 signalosome promotes angiotensin II-dependent vascular inflammation and atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Uncovering the roles of rare variants in common disease through whole-genome sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Genome-wide analysis of genetic loci associated with Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

1 reference

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6 September 2017

A method and server for predicting damaging missense mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Mild cognitive impairment: ten years later

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Exome sequencing identifies the cause of a mendelian disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Genetic diagnosis by whole exome capture and massively parallel DNA sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

The Allen Brain Atlas: 5 years and beyond

1 reference

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6 September 2017

Finding the missing heritability of complex diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

PolyADP-ribosylation is required for long-term memory formation in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

1 reference

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6 September 2017

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

1 reference

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6 September 2017

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

1 reference

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6 September 2017

The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods

1 reference

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6 September 2017

CARD-Bcl10-Malt1 signalosomes: missing link to NF-kappaB.

1 reference

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6 September 2017

Multiple roles for poly(ADP-ribose)polymerase-1 in neurological disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

1 reference

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6 September 2017

The role of poly(ADP-ribose) polymerase-1 in CNS disease

1 reference

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6 September 2017

Alzheimer's disease

1 reference

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6 September 2017

Nitric oxide, cell bioenergetics and neurodegeneration.

1 reference

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6 September 2017

Poly(ADP-ribose) polymerase: the nuclear target in signal transduction and its role in brain ischemia-reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Long-term memory requires polyADP-ribosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

1 reference

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6 September 2017

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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6 September 2017

Mapping the evolution of regional atrophy in Alzheimer's disease: unbiased analysis of fluid-registered serial MRI.

1 reference

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6 September 2017

Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

1 reference

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6 September 2017

Voxel-based morphometry–the methods

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6 September 2017

Mild cognitive impairment: clinical characterization and outcome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3777294

6 September 2017

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

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6 September 2017

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

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6 September 2017

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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6 September 2017

Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.

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14 September 2017

Heritability for Alzheimer's disease: the study of dementia in Swedish twins

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26 June 2018

High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease.

1 reference

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3 September 2018

Implication of common and disease specific variants in CLU, CR1, and PICALM.

1 reference

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3 September 2018

Exome sequencing and subsequent association studies identify five amino acid-altering variants influencing human height

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3 September 2018

2011 Alzheimer's disease facts and figures

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3 September 2018

Evaluation of the poly(ADP-ribose) polymerase-1 gene variants in Alzheimer's disease.

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3 September 2018

Interaction between poly(ADP-ribose) polymerase 1 and interleukin 1A genes is associated with Alzheimer's disease risk

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3 September 2018

Change in cognitive function in Alzheimer's disease in African-American and white persons.

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3 September 2018

Does Alzheimer's disease affect hippocampal asymmetry? Evidence from a cross-sectional and longitudinal volumetric MRI study

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3 September 2018

Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease

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3 September 2018

Heredity in dementia of the Alzheimer type.

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3 September 2018

Stopping a thief and killer: Alzheimer's disease crisis demands greater commitment to research

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21 January 2018

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases

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21 January 2018

Hypoxia induces c-fos transcription via a mitogen-activated protein kinase-dependent pathway

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12 December 2020

based on heuristic

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Dysregulation of monocytic nuclear factor-kappa B by oxidized low-density lipoprotein

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12 December 2020

based on heuristic

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The role of heredity in late-onset Alzheimer disease and vascular dementia. A twin study

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12 December 2020

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The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/MP.2013.24

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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