(Q37183293)

18 August 2017

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title

Methylglyoxal, diabetes mellitus and diabetic complications (English)

1 reference

18 August 2017

David L Vander Jagt

1

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18 August 2017

publication date

1 January 2008

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Drug Metabolism and Drug Interactions

18 August 2017

published in

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18 August 2017

volume

23

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18 August 2017

issue

1-2

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18 August 2017

page(s)

93-124

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CELL DIVISION AND CANCER.

18 August 2017

cites work

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21 January 2018

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21 January 2018

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Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond

21 January 2018

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Biochemistry and molecular cell biology of diabetic complications

21 January 2018

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AGE, RAGE, and ROS in diabetic nephropathy.

21 January 2018

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Aldose reductase in diabetic microvascular complications

21 January 2018

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Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options

21 January 2018

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Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health

21 January 2018

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Role of reactive aldehyde in cardiovascular diseases

21 January 2018

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Protein-bound acrolein: potential markers for oxidative stress

21 January 2018

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Oxidative stress in diabetes

21 January 2018

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Oxidative stress indices in IDDM subjects with and without long-term diabetic complications

21 January 2018

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Formation of reactive intermediates from Amadori compounds under physiological conditions

21 January 2018

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Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls.

21 January 2018

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Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite.

21 January 2018

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Characterization and detection of lysine-arginine cross-links derived from dehydroascorbic acid

21 January 2018

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Protein cross-linkage induced by formaldehyde derived from semicarbazide-sensitive amine oxidase-mediated deamination of methylamine.

21 January 2018

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Diabetes and semicarbazide-sensitive amine oxidase (SSAO) activity: a review

21 January 2018

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Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications

21 January 2018

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Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

21 January 2018

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Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes

21 January 2018

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The human red blood cell glyoxalase system in diabetes mellitus.

21 January 2018

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Evidence of high levels of methylglyoxal in cultured Chinese hamster ovary cells

21 January 2018

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Copper, zinc, and magnesium levels in non-insulin dependent diabetes mellitus

21 January 2018

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Oxidative modification of human ceruloplasmin by methylglyoxal: an in vitro study.

21 January 2018

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Reactive oxygen species as a signal in glucose-stimulated insulin secretion

21 January 2018

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Cytotoxic action of methylglyoxal on insulin-secreting cells

21 January 2018

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Methylglyoxal causes swelling and activation of a volume-sensitive anion conductance in rat pancreatic beta-cells

21 January 2018

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Structural and functional changes in human insulin induced by methylglyoxal

21 January 2018

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Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Advanced glycosylation: chemistry, biology, and implications for diabetes and aging

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Role of nonenzymatic glycosylation in the development of the sequelae of diabetes mellitus

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Advanced protein glycosylation in diabetes and aging

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

An agent cleaving glucose-derived protein crosslinks in vitro and in vivo

21 January 2018

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Breakers of advanced glycation end products restore large artery properties in experimental diabetes.

21 January 2018

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Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Carbonyl Stress and Diabetic Complications

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Glycation, carbonyl stress, EAGLEs, and the vascular complications of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

21 January 2018

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https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Aminoacetone induces iron-mediated oxidative damage to isolated rat liver mitochondria.

21 January 2018

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The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

21 January 2018

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Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Changes in the erythrocyte glutathione concentration in the course of diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Substrate-induced up-regulation of aldose reductase by methylglyoxal, a reactive oxoaldehyde elevated in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Methylglyoxal downregulates Raf-1 protein through a ubiquitination-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Methylglyoxal-bovine serum albumin stimulates tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen-activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Genotoxicity of advanced glycation end products: involvement of oxidative stress and of angiotensin II type 1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

The pro-oxidant role of methylglyoxal in mesenteric artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Aberrant accumulation of fibulin-3 in the endoplasmic reticulum leads to activation of the unfolded protein response and VEGF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Correlation between erythrocyte aldose reductase level and human diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

cDNA Cloning and Characterization of Human Glyoxalase I Isoforms from HT-1080 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Common polymorphisms in the glyoxalase-1 gene and their association with pro-thrombotic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

An (A-C)n dinucleotide repeat polymorphic marker at the 5' end of the aldose reductase gene is associated with early-onset diabetic retinopathy in NIDDM patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Polymorphisms of the aldose reductase gene and susceptibility to diabetic microvascular complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

(AC)(n) polymorphism of aldose reductase gene and diabetic microvascular complications in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

Aldose reductase gene polymorphisms and susceptibility to microvascular complications in Type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FDMDI.2008.23.1-2.93

10.1515/DMDI.2008.23.1-2.93

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference