(Q37188498)

English

Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks

scientific article published on April 2011

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks (English)

1 reference

Europe PubMed Central

18 August 2017

ubiquitin-proteasome system

0 references

0 references

author name string

Ae Jeong Kim

1

1 reference

Europe PubMed Central

18 August 2017

Hyun-Ju Kim

2

1 reference

Europe PubMed Central

18 August 2017

Hye Jin Jee

3

1 reference

Europe PubMed Central

18 August 2017

Naree Song

4

1 reference

Europe PubMed Central

18 August 2017

Minjee Kim

5

1 reference

Europe PubMed Central

18 August 2017

Yoe-Sik Bae

6

1 reference

Europe PubMed Central

18 August 2017

Jay H Chung

7

1 reference

Europe PubMed Central

18 August 2017

Jeanho Yun

8

1 reference

Europe PubMed Central

18 August 2017

language of work or name

0 references

publication date

1 April 2011

1 reference

Europe PubMed Central

18 August 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Biochimica et Biophysica Acta

1 reference

Europe PubMed Central

18 August 2017

1813

1 reference

Europe PubMed Central

18 August 2017

6

1 reference

Europe PubMed Central

18 August 2017

1230-1238

1 reference

Europe PubMed Central

18 August 2017

The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Genetic polymorphisms and micronucleus formation: a review of the literature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Chk1- and claspin-dependent but ATR/ATM- and Rad17-independent DNA replication checkpoint response in HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Chk1 is haploinsufficient for multiple functions critical to tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Tumor microenvironmental physiology and its implications for radiation oncology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Degradation of Transcription Repressor ZBRK1 through the Ubiquitin-Proteasome Pathway Relieves Repression of Gadd45a upon DNA Damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Chk1 and Chk2 kinases in checkpoint control and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Metabolic mapping with bioluminescence: basic and clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Mechanisms underlying ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

The DNA damage response: putting checkpoints in perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

The ubiquitin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Replication checkpoint enforced by kinases Cds1 and Chk1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Structure and functions of the 20S and 26S proteasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Geographical mapping of metabolites in biological tissue with quantitative bioluminescence and single photon imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

6 September 2017

Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

14 September 2017

Regulation of DNA topoisomerase IIalpha stability by the ECV ubiquitin ligase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

14 September 2017

Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

14 September 2017

Ischemia-induced K-ras mutations in human colorectal cancer cells: role of microenvironmental regulation of MSH2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

14 September 2017

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

14 September 2017

Tumor hypoxia: its impact on cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

14 September 2017

Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

28 September 2017

DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

28 September 2017

Microenvironmental influences on mutagenesis in mammary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779427

3 September 2018

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21440578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21440578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic instability in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21440578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenesis induced by the tumor microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21440578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21440578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/21440578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix

1 reference

https://pubmed.ncbi.nlm.nih.gov/21440578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBAMCR.2011.03.012

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

ResearchGate publication ID

0 references

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