(Q37192883)

18 August 2017

Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease (English)

1 reference

18 August 2017

phase II clinical trial

0 references

0 references

13

Paul S Aisen

1 reference

18 August 2017

7

Martin R Farlow

1 reference

18 August 2017

14

Leon J Thal

1 reference

18 August 2017

9

Elaine R Peskind

1 reference

18 August 2017

Adam S Fleisher

1

1 reference

18 August 2017

Rema Raman

2

1 reference

18 August 2017

Eric R Siemers

3

1 reference

18 August 2017

Lida Becerra

4

1 reference

18 August 2017

Christopher M Clark

5

1 reference

18 August 2017

Robert A Dean

6

1 reference

18 August 2017

James E Galvin

8

1 reference

18 August 2017

Joseph F Quinn

10

1 reference

18 August 2017

Abdullah Sherzai

11

1 reference

18 August 2017

B Brooke Sowell

12

1 reference

18 August 2017

1 August 2008

1 reference

18 August 2017

Archives of Neurology

1 reference

18 August 2017

65

1 reference

18 August 2017

8

1 reference

18 August 2017

1031-1038

1 reference

Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Implication of APP secretases in notch signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

An inventory to assess activities of daily living for clinical trials in Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Clusterin (Apo J) protects against in vitro amyloid-beta (1-40) neurotoxicity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

The Alzheimer's Disease Assessment Scale

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Safety, tolerability, and effects on plasma and cerebrospinal fluid amyloid-beta after inhibition of gamma-secretase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682361

10.1001/ARCHNEUR.65.8.1031

3 September 2018

Identifiers

DOI

1 reference

release_gyhhirnpprfgtbb4j36r6o4bpi

18 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gyhhirnpprfgtbb4j36r6o4bpi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

18 August 2017

PubMed publication ID

18695053

1 reference