(Q37195520)

18 August 2017

SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment (English)

1 reference

18 August 2017

Y Sun

1

1 reference

18 August 2017

D Zhu

2

1 reference

18 August 2017

F Chen

3

1 reference

18 August 2017

M Qian

4

1 reference

18 August 2017

H Wei

5

1 reference

18 August 2017

W Chen

6

1 reference

18 August 2017

J Xu

7

1 reference

18 August 2017

language of work or name

English

0 references

publication date

11 January 2016

1 reference

18 August 2017

1 reference

18 August 2017

35

1 reference

18 August 2017

33

1 reference

18 August 2017

4321-4334

1 reference

Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

18 August 2017

start time

11 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/onc.2015.494

0 references

cites work

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

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New horizons in tumor microenvironment biology: challenges and opportunities

9 September 2017

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Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma

9 September 2017

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Translational horizons in the tumor microenvironment: harnessing breakthroughs and targeting cures

9 September 2017

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DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance.

9 September 2017

1 reference

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Microenvironmental regulation of therapeutic response in cancer

9 September 2017

1 reference

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Systemic therapy in men with metastatic castration-resistant prostate cancer:American Society of Clinical Oncology and Cancer Care Ontario clinical practice guideline

9 September 2017

1 reference

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Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?

9 September 2017

1 reference

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Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy

9 September 2017

1 reference

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Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

p38MAPK plays a crucial role in stromal-mediated tumorigenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responses.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

CD44 expressed on cancer-associated fibroblasts is a functional molecule supporting the stemness and drug resistance of malignant cancer cells in the tumor microenvironment

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Prognostic model predicting metastatic castration-resistant prostate cancer survival in men treated with second-line chemotherapy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Targeting cancer stem cells to suppress acquired chemotherapy resistance

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Cancer drug resistance: an evolving paradigm

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Cell-autonomous and non-cell-autonomous mechanisms of HGF/MET-driven resistance to targeted therapies: from basic research to a clinical perspective

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

WNT signalling pathways as therapeutic targets in cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Glucocorticoids suppress selected components of the senescence-associated secretory phenotype

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

The role of secreted frizzled-related protein 2 expression in prostate cancer.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

The complex roles of Wnt antagonists in RCC.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

The role of calcineurin/NFAT in SFRP2 induced angiogenesis--a rationale for breast cancer treatment with the calcineurin inhibitor tacrolimus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Drug resistance in metastatic castration-resistant prostate cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

The distribution of secondary growths in cancer of the breast. 1889

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

The structural basis of DKK-mediated inhibition of Wnt/LRP signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Molecular pathways: involving microenvironment damage responses in cancer therapy resistance

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4994019

Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin-angiotensin system

3 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.494

The tumor microenvironment controls drug sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.494

Tumor microenvironment and cancer therapy resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.494

Preoperative hepatic and regional arterial chemotherapy in the prevention of liver metastasis after colorectal cancer surgery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.494

[Tumor microenvironment in pathogenesis and drug resistance of non-Hodgkin's lymphoma]

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26751775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Tumor microenvironment and therapeutic resistance process]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26751775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2015.494

1 reference

18 August 2017

1 reference

18 August 2017

1 reference