(Q37949269)

25 August 2017

title

The complex roles of Wnt antagonists in RCC. (English)

1 reference

25 August 2017

2

Shahana Majid

1 reference

25 August 2017

3

Rajvir Dahiya

1 reference

25 August 2017

Sharanjot Saini

1

1 reference

25 August 2017

language of work or name

English

0 references

publication date

25 October 2011

1 reference

25 August 2017

published in

Nature Reviews Urology

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25 August 2017

volume

8

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25 August 2017

issue

12

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25 August 2017

page(s)

690-699

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Histopathology and molecular genetics of renal tumors toward unification of a classification system

25 August 2017

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Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription

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A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

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The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

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Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in Xenopus

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Secreted antagonists of the Wnt signalling pathway

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The advantages and disadvantages of sfrp1 and sfrp2 expression in pathological events.

21 January 2018

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Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

21 January 2018

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Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.

21 January 2018

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SARPs: a family of secreted apoptosis-related proteins

21 January 2018

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Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis

21 January 2018

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The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling

21 January 2018

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A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors

21 January 2018

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Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction

21 January 2018

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Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

The NTR module: domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

A new secreted protein that binds to Wnt proteins and inhibits their activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted WNT antagonists as tumor suppressors: pro and con.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Functional and structural diversity of the human Dickkopf gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

DKK1 antagonizes Wnt signaling without promotion of LRP6 internalization and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

The many ways of Wnt in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Frequent loss of SFRP1 expression in multiple human solid tumours: association with aberrant promoter methylation in renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Epigenetic alterations of the Wnt/beta-catenin pathway in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Detection of loss of heterozygosity in the APC tumor suppressor gene in nonpapillary renal cell carcinoma by microdissection and polymerase chain reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

MBD2 deficiency does not accelerate p53 mediated lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Role of secreted frizzled-related protein 3 in human renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Functional significance of secreted Frizzled-related protein 1 in metastatic renal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Roles of secreted frizzled-related proteins in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

The Wnt antagonist sFRP1 in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted Frizzled-related proteins can regulate metanephric development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Hypermethylation of SFRP2 as a potential marker for stool-based detection of colorectal cancer and precancerous lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Frzb-1, an antagonist of Wnt-1 and Wnt-8, does not block signaling by Wnts -3A, -5A, or -11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Severe suppression of Frzb/sFRP3 transcription in osteogenic sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Wnt antagonist gene polymorphisms and renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Wnt antagonist DICKKOPF-3 (Dkk-3) induces apoptosis in human renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

DICKKOPF-4 activates the noncanonical c-Jun-NH2 kinase signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Wise, a context-dependent activator and inhibitor of Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

SOSTDC1 differentially modulates Smad and beta-catenin activation and is down-regulated in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

A human bone morphogenetic protein antagonist is down-regulated in renal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Cancer. The metastasis cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted Frizzled Related Protein 1 Is Overexpressed in Uterine Leiomyomas, Associated with a High Estrogenic Environment and Unrelated to Proliferative Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Autocrine/paracrine secreted Frizzled-related protein 2 induces cellular resistance to apoptosis: a possible mechanism of mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

sFRP-1 binds via its netrin-related motif to the N-module of thrombospondin-1 and blocks thrombospondin-1 stimulation of MDA-MB-231 breast carcinoma cell adhesion and migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Dickkopf-3/REIC functions as a suppressor gene of tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Alteration of frizzled expression in renal cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

beta-catenin expression and mutational analysis in renal cell carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Mutational state of von Hippel-Lindau and adenomatous polyposis coli genes in renal tumors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Apc deficiency predisposes to renal carcinoma in the mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Functional significance of Wnt inhibitory factor-1 gene in kidney cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

Secreted frizzled related protein 1 is overexpressed in uterine leiomyomas, associated with a high estrogenic environment and unrelated to proliferative activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.146

IGFBP-4 activates the Wnt/beta-catenin signaling pathway and induces M-CAM expression in human renal cell carcinoma

31 March 2020

1 reference

12 December 2020

Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms' tumors.

1 reference

12 December 2020

WNT/PCP signaling pathway and human cancer (review).

1 reference

12 December 2020

The human T-cell factor-4 gene splicing isoforms, Wnt signal pathway, and apoptosis in renal cell carcinoma.

1 reference

12 December 2020

Expression of beta-catenin in renal cell carcinoma

1 reference

12 December 2020

A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling.

1 reference

12 December 2020

Targeted therapy for metastatic renal cell carcinoma: a home run or a work in progress?

1 reference

12 December 2020

Methylation-associated silencing of SFRP1 in renal cell carcinoma.

1 reference

12 December 2020

Altered expression of beta-catenin in renal cell cancer and transitional cell cancer with the absence of beta-catenin gene mutations

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRUROL.2011.146

1 reference

release_blidbt53cngz3n3dbmd2ygluga

25 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/blidbt53cngz3n3dbmd2ygluga

24 November 2022

mapped directly with Wikidata item

1 reference