(Q37198586)

18 August 2017

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title

The ADRB3 Trp64Arg variant and BMI: a meta-analysis of 44 833 individuals (English)

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18 August 2017

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7

R J F Loos

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18 August 2017

5

N J Wareham

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18 August 2017

N Kurokawa

1

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18 August 2017

E H Young

2

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18 August 2017

Y Oka

3

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18 August 2017

H Satoh

4

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18 August 2017

M S Sandhu

6

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18 August 2017

language of work or name

English

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publication date

24 June 2008

1 reference

International Journal of Obesity

18 August 2017

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18 August 2017

32

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18 August 2017

8

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18 August 2017

1240-1249

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https://scigraph.springernature.com/pub.10.1038/ijo.2008.90

18 August 2017

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cites work

The human obesity gene map: the 2005 update

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https://api.crossref.org/works/10.1038%2FIJO.2008.90

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Meta-analysis of the association of Trp64Arg polymorphism of beta 3-adrenergic receptor gene with body mass index.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Association of BMI with the beta3-adrenergic receptor gene polymorphism in Japanese: meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

A mutation in the beta 3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Phenotypic characterization of the Trp64Arg polymorphism in the beta 3-adrenergic receptor gene in normal weight and obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Molecular scanning for mutations in the beta 3-adrenergic receptor gene in Nauruans with obesity and noninsulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The Trp64Arg mutation of the beta3 adrenergic receptor gene has no effect on obesity phenotypes in the Québec Family Study and Swedish Obese Subjects cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Role of the beta 3-adrenergic receptor locus in obesity and noninsulin-dependent diabetes among members of Caucasian families with a diabetic sibling pair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Beta 3-adrenergic-receptor polymorphism: a genetic marker for visceral fat obesity and the insulin resistance syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Prevalence of the Trp64Arg missense mutation of the beta3-adrenergic receptor gene in Japanese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Association of a genetic variation in the beta 3-adrenergic receptor gene with coronary heart disease among Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Beta 3-adrenergic receptor gene polymorphism is not a major genetic determinant of obesity and diabetes in Japanese general population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Expression of the beta 3-adrenoceptor gene polymorphism (Trp64Arg) in obese diabetic and non-diabetic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

TRP64ARG β3-adrenergic receptor and obesity in Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The Trp64Arg mutation of the beta3-adrenergic receptor is associated with hyperglycemia and current body mass index in Jamaican women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Clinical features associated with the homozygous Trp64Arg mutation of the beta3-adrenergic receptor: no evidence for its association with obesity in Japanese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Association of the Trp64Arg mutation of the beta3-adrenergic receptor with fatty liver and mild glucose intolerance in Japanese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Lack of associations between serum leptin, a polymorphism in the gene for the beta 3-adrenergic receptor and glucose tolerance in the Dutch population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Beta 3-adrenoreceptor gene polymorphism and leptin. Lack of relationship in type 2 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Contribution of a missense mutation (Trp64Arg) in beta3-adrenergic receptor gene to multiple risk factors in Japanese men with hyperuricemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Additive effects of the mutations in the beta3-adrenergic receptor and uncoupling protein-1 genes on weight loss and weight maintenance in Finnish women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

A Trp 64 Arg mutation in the beta3-adrenergic receptor gene is not associated with moderate overweight in Japanese workers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Polymorphism of the human beta3-adrenoceptor gene forms a well-conserved haplotype that is associated with moderate obesity and altered receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Association of Trp64Arg beta 3-adrenergic-receptor gene polymorphism with essential hypertension in the Sardinian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The W64R variant of the beta3-adrenergic receptor is not associated with type II diabetes or obesity in a large Finnish sample.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Polymorphism of the beta3-adrenergic receptor gene and weight gain in pregnant diabetic women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Phenotypic characterization of the beta3-adrenergic receptor mutation and the uncoupling protein 1 polymorphism in Japanese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Lack of association between genetic variation in the beta3-adrenergic receptor gene and insulin resistance in patients with coronary heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

A study on the genetics of obesity: influence of polymorphisms of the beta-3-adrenergic receptor and insulin receptor substrate 1 in relation to weight loss, waist to hip ratio and frequencies of common cardiovascular risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Study of the Trp64Arg polymorphism of the beta3-adrenergic receptor in Greek women with gestational diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Genetic and environmental nature of the insulin resistance syndrome in Indo-Mauritian subjects with premature coronary heart disease: contribution of beta3-adrenoreceptor gene polymorphism and beta blockers on triglyceride and HDL concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Beta 3-adrenergic receptor gene polymorphism and type 2 diabetes in a Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Relationship of the Trp64Arg polymorphism of the beta3-adrenoceptor gene to central adiposity and high blood pressure: interaction with age. Cross-sectional and longitudinal findings of the Olivetti Prospective Heart Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Possible association of beta2- and beta3-adrenergic receptor gene polymorphisms with susceptibility to breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-adrenergic receptor is associated with type 2 diabetes and obesity in a large Japanese sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Beta(3)-adrenergic receptor gene variant is associated with upper body obesity only in obese Japanese-American men but not in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Gender specific associations of the Trp64Arg mutation in the beta3-adrenergic receptor gene with obesity-related phenotypes in a Mediterranean population: interaction with a common lipoprotein lipase gene variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Effects of intestinal fatty acid-binding protein gene Ala54Thr polymorphism and beta3-adrenergic receptor gene Trp64Arg polymorphism on insulin resistance and fasting plasma glucose in young to older Japanese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

No evidence for an association between genetic polymorphisms of beta(2)- and beta(3)-adrenergic receptor genes with body mass index in Aymara natives from Chile

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The polymorphism of the beta3-adrenergic receptor gene is associated with reduced low-density lipoprotein particle size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Arg64β3‐Adrenoceptor Variant and the Components of Energy Expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

No interactions between polymorphisms in the beta3-adrenergic receptor gene and the PPAR-gamma gene on the risk of the insulin resistance syndrome in the Danish MONICA cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Effects of uncoupling protein 1 and ß3-adrenergic receptor gene polymorphisms on body size and serum lipid concentrations in Japanese women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The Trp(64)Arg polymorphism of the beta(3)-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: a longitudinal analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Polymorphism of Trp64Arg in beta3-adrenergic receptor gene among Bolivian people in rural areas at high and low altitudes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The Trp64Arg polymorphism of the beta3-adrenergic receptor is not increased in women with preeclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Lack of relationship between beta3-adrenergic receptor gene polymorphism and gestational diabetes mellitus in a Taiwanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The Arg64 allele of the beta 3-adrenoceptor gene but not the -3826G allele of the uncoupling protein 1 gene is associated with increased leptin levels in the Spanish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Trp64Arg polymorphism of the beta3-adrenergic receptor gene, pre-pregnancy obesity and risk of pre-eclampsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Tryptophan 64 --> arginine polymorphism of beta-3-adrenergic receptor in Chilean women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

No association of the Trp 64 Arg mutation of the beta3-adrenergic receptor gene with obesity, type 2 diabetes mellitus, hyperlipidemia, and hypertension in Japanese patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Association between beta-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Beta3-adrenergic receptor gene, body mass index, bone mineral density and fracture risk in elderly men and women: the Dubbo Osteoporosis Epidemiology Study (DOES).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Polymorphisms of insulin receptor substrate 1 and beta3-adrenergic receptor genes in gestational diabetes and normal pregnancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

beta2- and beta3-Adrenoceptor polymorphisms relate to subsequent weight gain and blood pressure elevation in obese normotensive individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The biochemical effect of the naturally occurring Trp64-->Arg mutation on human beta3-adrenoceptor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Trp64Arg mutation of beta3-adrenoceptor gene deteriorates lipolysis induced by beta3-adrenoceptor agonist in human omental adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Pharmacological characterization of a recently described human beta 3- adrenergic receptor mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Relationship between metabolic syndrome and Trp64arg polymorphism of the beta-adrenergic receptor gene in a general sample: the Shigaraki study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

The Trp64Arg polymorphism of the β3-adrenergic receptor gene and obesity in Chinese subjects with components of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Genetic Influences of .BETA.-Adrenoceptor Polymorphisms on Arterial Functional Changes and Cardiac Remodeling in Hypertensive Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

UKPDS 19: Heterogeneity in NIDDM: separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Mutation of beta 3-adrenergic-receptor gene and response to treatment of obesity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Genetic variation in the beta3-adrenergic receptor in Japanese NIDDM patients

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Insulin sensitivity and body weight changes in young white carriers of the codon 64 amino acid polymorphism of the beta 3-adrenergic receptor gene

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Genetic variation in the beta 3-adrenergic receptor in Japanese NIDDM patients

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

The beta 3-adrenergic receptor gene Trp64Arg mutation is overrepresented in obese women. Effects on weight, BMI, abdominal fat, blood pressure, and reproductive history in an elderly Australian population

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Trp64Arg substitution in the beta 3-adrenergic receptor does not relate to body weight in healthy, premenopausal women

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Trp64Arg mutation of beta 3-adrenergic receptor and insulin sensitivity in subjects with glucose intolerance

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

The beta(3)-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Eskimos

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

W64R mutation in beta-3-adrenergic receptor gene and weight in a large population sample

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Trp64Arg mutation of beta3-adrenoceptor gene is associated with diabetic nephropathy in Type II diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Genetic variation in the beta-3-adrenergic receptor in essential hypertension

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

The Trp64Arg polymorphism of the beta3-adrenergic receptor gene is associated with hypertension in men with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Frequency of and interaction between polymorphisms in the beta3-adrenergic receptor and in uncoupling proteins 1 and 2 and obesity in Germans

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

The beta 3-adrenergic receptor gene and obesity in a population sample of African Americans

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

The impact of Trp64Arg mutation in the beta3-adrenergic receptor gene on haemodialysis patients

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Synergistic effect of polymorphisms of uncoupling protein 1 and beta3-adrenergic receptor genes on autonomic nervous system activity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Difficulty in losing weight by behavioral intervention for women with Trp64Arg polymorphism of the beta3-adrenergic receptor gene

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Phenotypic linkage between single-nucleotide polymorphisms of beta3-adrenergic receptor gene and NADH dehydrogenase subunit-2 gene, with special reference to eating behavior

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Additive effect of the mutations in the beta3-adrenoceptor gene and UCP3 gene promoter on body fat distribution and glycemic control after weight reduction in overweight subjects with CAD or metabolic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Increased risk of obesity resulting from the interaction between high energy intake and the Trp64Arg polymorphism of the beta3-adrenergic receptor gene in healthy Japanese men

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Impact of variation inADRB2, ADRB3, andGNB3 genes on body mass index and waist circumference in a Brazilian population

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Comparison of body fat distribution and blood lipid profiles according to Trp64Arg polymorphism for the beta 3-adrenergic receptor gene in Korean middle-aged women.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

LEPR, ADBR3, IRS-1 and 5-HTT genes polymorphisms do not associate with obesity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Mutated human beta3-adrenergic receptor (Trp64Arg) lowers the response to beta3-adrenergic agonists in transfected 3T3-L1 preadipocytes

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Pharmacological characterization of a recently described human beta 3-adrenergic receptor mutant

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.90

7 January 2021

Identifiers

DOI

10.1038/IJO.2008.90

1 reference

18 August 2017

1 reference