(Q37203980)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

17

1 reference

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20 February 2020

Søren Warming

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

20

Merone Roose-Girma

1 reference

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20 February 2020

author name string

Shahram Misaghi

1

1 reference

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20 February 2020

Kate Senger

2

1 reference

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20 February 2020

Tao Sai

3

1 reference

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20 February 2020

Yan Qu

4

1 reference

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20 February 2020

Yonglian Sun

5

1 reference

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20 February 2020

Kajal Hamidzadeh

6

1 reference

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20 February 2020

Allen Nguyen

7

1 reference

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20 February 2020

Zhaoyu Jin

8

1 reference

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20 February 2020

Meijuan Zhou

9

1 reference

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20 February 2020

Donghong Yan

10

1 reference

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20 February 2020

Wei Yu Lin

11

1 reference

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20 February 2020

Zhonghua Lin

12

1 reference

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20 February 2020

Maria N Lorenzo

13

1 reference

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20 February 2020

Andrew Sebrell

14

1 reference

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20 February 2020

Jiabing Ding

15

1 reference

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20 February 2020

Min Xu

16

1 reference

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20 February 2020

Cary D Austin

18

1 reference

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20 February 2020

Mercedesz Balazs

19

1 reference

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20 February 2020

Laura DeForge

21

1 reference

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20 February 2020

Wyne P Lee

23

1 reference

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20 February 2020

Vishva M Dixit

24

1 reference

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20 February 2020

Ali A Zarrin

25

1 reference

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20 February 2020

language of work or name

English

0 references

publication date

9 September 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

20 February 2020

published in

1 reference

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20 February 2020

volume

110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

issue

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

15770-15775

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

Critical role of activation induced cytidine deaminase in experimental autoimmune encephalomyelitis.

20 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Origin of immunoglobulin isotype switching

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Evolutionarily conserved paired immunoglobulin-like receptor α (PILRα) domain mediates its interaction with diverse sialylated ligands

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Sequential class switching is required for the generation of high affinity IgE antibodies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

The IgH locus 3' regulatory region: pulling the strings from behind

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Omalizumab for asthma: indications, off-label uses and future directions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

PTIP promotes chromatin changes critical for immunoglobulin class switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

The development of allergic inflammation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

A role for AID in chromosome translocations between c-myc and the IgH variable region.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

IgH class switching and translocations use a robust non-classical end-joining pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Molecular mechanisms of antibody somatic hypermutation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Myc translocations in B cell and plasma cell neoplasms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Influence of switch region length on immunoglobulin class switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

ATM is required for efficient recombination between immunoglobulin switch regions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Internal IgH class switch region deletions are position-independent and enhanced by AID expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Mechanism and control of class-switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, A role for G-G pairing in immunoglobulin switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Immunoglobulin switch circular DNA in the mouse infected with Nippostrongylus brasiliensis: evidence for successive class switching from mu to epsilon via gamma 1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Antibody class switching mediated by yeast endonuclease-generated DNA breaks.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Frequency of immunoglobulin E class switching is autonomously determined and independent of prior switching to other classes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Human Ig S gamma regions and their participation in sequential switching to IgE.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

An evolutionarily conserved target motif for immunoglobulin class-switch recombination

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Deregulated PAX-5 transcription from a translocated IgH promoter in marginal zone lymphoma.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3785764

Establishment of antigen-specific IgE transgenic mice to study pathological and immunobiological roles of IgE in vivo

3 September 2018

1 reference

12 December 2020

Expression and biological effects of high levels of serum IgE in epsilon heavy chain transgenic mice

1 reference

12 December 2020

IL-4 induction of IgE class switching by lipopolysaccharide-activated murine B cells occurs predominantly through sequential switching

1 reference

12 December 2020

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1221661110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

24019479

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019479%20AND%20SRC:MED&resulttype=core&format=json