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Does autophagy have a license to kill mammalian cells?
scientific article published on 04 July 2008
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
review article
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title
Does autophagy have a license to kill mammalian cells?
(English)
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
main subject
autophagy
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author
Riccarda Granata
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2
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author name string
F Scarlatti
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1
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Europe PubMed Central
PubMed publication ID
18600232
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
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10 January 2020
A J Meijer
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3
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PubMed publication ID
18600232
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10 January 2020
P Codogno
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4
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PubMed publication ID
18600232
reference URL
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10 January 2020
publication date
4 July 2008
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
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retrieved
10 January 2020
published in
Cell Death & Differentiation
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
volume
16
1 reference
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
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10 January 2020
issue
1
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
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retrieved
10 January 2020
page(s)
12-20
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Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
cites work
Autophagy fights disease through cellular self-digestion
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7 January 2021
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7 January 2021
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7 January 2021
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7 January 2021
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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
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7 January 2021
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The role of autophagy during the early neonatal starvation period
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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
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https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
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https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
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Induction of autophagy during extracellular matrix detachment promotes cell survival
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7 January 2021
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Consequences of the selective blockage of chaperone-mediated autophagy
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7 January 2021
based on heuristic
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Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus
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7 January 2021
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GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation.
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Developmental cell death: morphological diversity and multiple mechanisms
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7 January 2021
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Autophagy and cell death.
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https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Self-eating and self-killing: crosstalk between autophagy and apoptosis
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7 January 2021
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Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila
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7 January 2021
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The inositol 1,4,5-trisphosphate receptor is required to signal autophagic cell death
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7 January 2021
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Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation
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7 January 2021
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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
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https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
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inferred from DOI database lookup
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
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7 January 2021
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inferred from DOI database lookup
Autophagic programmed cell death by selective catalase degradation
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7 January 2021
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A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death
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7 January 2021
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Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease?
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Autophagy plays a protective role during zVAD-induced necrotic cell death.
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Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.
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The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
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Regulation of autophagy by cytoplasmic p53
1 reference
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7 January 2021
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inferred from DOI database lookup
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
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Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4.
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NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy
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Autophagy and NF-kappaB: fight for fate
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Autophagy gene-dependent clearance of apoptotic cells during embryonic development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of autophagy in cancer development and response to therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
A picky eater: exploring the mechanisms of selective autophagy in human pathologies
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lost to translation: when autophagy targets mature ribosomes
1 reference
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https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rapamycin pre-treatment protects against apoptosis
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ROS, mitochondria and the regulation of autophagy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of macroautophagy by mTOR and Beclin 1 complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role and regulation of starvation-induced autophagy in the Drosophila fat body
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autophagy and p70S6 kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FoxO3 controls autophagy in skeletal muscle in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 inhibition of autophagy: a new route to cancer?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
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7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F1 regulates autophagy and the transcription of autophagy genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of chromatin immunoprecipitation to clone novel E2F target promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physiological control of metabolic flux: the requirement for multisite modulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The INK4a/ARF network in tumour suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell death in unusual but informative and beautiful model organisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2008.101
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/CDD.2008.101
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
PubMed publication ID
18600232
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18600232
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600232%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
ResearchGate publication ID
5251554
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