(Q37207076)

18 August 2017

Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug (English)

1 reference

18 August 2017

0 references

Grant R Zimmermann

1

1 reference

18 August 2017

William Avery

2

1 reference

18 August 2017

Alyce L Finelli

3

1 reference

18 August 2017

Melissa Farwell

4

1 reference

18 August 2017

Christopher C Fraser

5

1 reference

18 August 2017

Alexis A Borisy

6

1 reference

18 August 2017

26 January 2009

1 reference

Arthritis Research and Therapy

18 August 2017

1 reference

18 August 2017

11

1 reference

18 August 2017

R12

1 reference

18 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1186/ar2602

18 August 2017

0 references

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Role of the RNA-binding protein tristetraprolin in glucocorticoid-mediated gene regulation.

6 September 2017

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Translational therapeutics of dipyridamole

6 September 2017

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Antiinflammatory glucocorticoid receptor ligand with reduced side effects exhibits an altered protein-protein interaction profile

6 September 2017

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Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis

6 September 2017

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EULAR evidence-based recommendations on the management of systemic glucocorticoid therapy in rheumatic diseases.

6 September 2017

1 reference

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Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor?

6 September 2017

1 reference

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Glucocorticoid receptor action in beneficial and side effects of steroid therapy: lessons from conditional knockout mice

6 September 2017

1 reference

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Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

6 September 2017

1 reference

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Effects of glucocorticoids on radiological progression in rheumatoid arthritis

6 September 2017

1 reference

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Annexin 1: the new face of an old molecule

6 September 2017

1 reference

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Multi-target therapeutics: when the whole is greater than the sum of the parts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

RANTES and chemotactic activity in synovial fluids from patients with rheumatoid arthritis and osteoarthritis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

A fully dissociated compound of plant origin for inflammatory gene repression

6 September 2017

1 reference

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Assessment of the clinical significance of gelatinase activity in patients with juvenile idiopathic arthritis using quantitative protein substrate zymography

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Post-transcriptional and nongenomic effects of glucocorticoids.

6 September 2017

1 reference

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Mechanisms of glucocorticoid receptor action in noninflammatory and inflammatory cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published evidence and prospective trial data.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Multicomponent therapeutics for networked systems

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Negative glucocorticoid receptor response elements and their role in glucocorticoid action

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Cancer genes and the pathways they control

6 September 2017

1 reference

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Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Systematic discovery of multicomponent therapeutics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

A novel antiinflammatory maintains glucocorticoid efficacy with reduced side effects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Mechanisms involved in the side effects of glucocorticoids

6 September 2017

1 reference

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Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ.

6 September 2017

1 reference

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Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Use of oral corticosteroids and risk of fractures.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

The DNA binding-independent function of the glucocorticoid receptor mediates repression of AP-1-dependent genes in skin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Glucocorticoid signalling--multiple variations of a common theme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Steroid receptor interactions with heat shock protein and immunophilin chaperones

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Serum corticosterone, interleukin-1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wistar strains

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Autoimmunity to type II collagen an experimental model of arthritis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E release.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Glucocorticoid regulation of corticotropin-releasing factor1 receptor expression in pituitary-derived AtT-20 cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Depolarization counteracts glucocorticoid inhibition of adenohypophysical corticotroph cells

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

A weak TATA box is a prerequisite for glucocorticoid-dependent repression of the osteocalcin gene

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Inhibition of human monocyte TNF production by adenosine receptor agonists

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Suppression of collagen-induced arthritis by combination cyclosporin A and methotrexate therapy

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Autoactivation profiles of calcium-dependent matrix metalloproteinase-2 and -9 in inflammatory synovial fluid: effect of pyrophosphate and bisphosphonates

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2688244

Effects of low-dose prednisolone on endothelial function, atherosclerosis, and traditional risk factors for atherosclerosis in patients with rheumatoid arthritis--a randomized study

3 September 2018

1 reference

12 December 2020

Uveitis and arthritis induced by adjuvant: clinical, immunologic and histologic characteristics

1 reference

12 December 2020

A new grammar for drug discovery

1 reference

12 December 2020

Revisiting the toxicity of low-dose glucocorticoids: risks and fears

1 reference

12 December 2020

RANTES and monocyte chemoattractant protein 1 as sensitive markers of disease activity in patients with juvenile rheumatoid arthritis: a six-year longitudinal study

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR2602

1 reference

Dimensions Publication ID

18 August 2017

0 references

1 reference

18 August 2017

1 reference