(Q37207646)

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21 February 2020

1 reference

29 April 2021

Understanding the role of NRF2-regulated miRNAs in human malignancies (English)

1 reference

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21 February 2020

1 reference

14 November 2020

1 reference

8 February 2021

nuclear factor erythroid 2-related factor 2

1 reference

29 April 2021

2

1 reference

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21 February 2020

Kristian Bowles

4

1 reference

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21 February 2020

David J MacEwan

5

1 reference

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21 February 2020

author name string

Niraj M Shah

1

1 reference

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21 February 2020

Megan Y Murray

3

1 reference

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21 February 2020

language of work or name

English

0 references

publication date

1 August 2013

7 references

3 April 2019

11 December 2019

22 December 2019

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21 February 2020

14 November 2020

8 February 2021

29 April 2021

7 references

3 April 2019

11 December 2019

22 December 2019

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21 February 2020

14 November 2020

8 February 2021

29 April 2021

4

1 reference

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21 February 2020

issue

8

1 reference

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21 February 2020

page(s)

1130-1142

1 reference

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Creative Commons Attribution 2.5 Generic

21 February 2020

copyright license

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3 April 2019

11 December 2019

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8 February 2021

on focus list of Wikimedia project

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ScienceSource

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6 September 2017

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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

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6 September 2017

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MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism

6 September 2017

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6 September 2017

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6 September 2017

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Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway

6 September 2017

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Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization

6 September 2017

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MicroRNA miR-125b causes leukemia

6 September 2017

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Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients

6 September 2017

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Targeting microRNAs in cancer: rationale, strategies and challenges

6 September 2017

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The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone

6 September 2017

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microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease

6 September 2017

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Expression of ABCG2 (BCRP) is regulated by Nrf2 in cancer cells that confers side population and chemoresistance phenotype

6 September 2017

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MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation

6 September 2017

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Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia

6 September 2017

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P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

6 September 2017

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Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth.

6 September 2017

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Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers

6 September 2017

1 reference

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Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

6 September 2017

1 reference

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Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma

6 September 2017

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MicroRNA expression signatures in Barrett's esophagus and esophageal adenocarcinoma

6 September 2017

1 reference

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Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

6 September 2017

1 reference

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MicroRNA profiling of human kidney cancer subtypes

6 September 2017

1 reference

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CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma -A miRNA microarray analysis

6 September 2017

1 reference

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Many roads to maturity: microRNA biogenesis pathways and their regulation

6 September 2017

1 reference

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Loss of Bcl-2 expression in colon cancer: a prognostic factor for recurrence in stage II colon cancer

6 September 2017

1 reference

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Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

6 September 2017

1 reference

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A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

6 September 2017

1 reference

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Mechanistic studies of the Nrf2-Keap1 signaling pathway

6 September 2017

1 reference

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The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

miR-15 and miR-16 induce apoptosis by targeting BCL2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Extensive modulation of a set of microRNAs in primary glioblastoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

MicroRNAs modulate hematopoietic lineage differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

miR-125b is methylated and functions as a tumor suppressor by regulating the ETS1 proto-oncogene in human invasive breast cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Cul3 overexpression depletes Nrf2 in breast cancer and is associated with sensitivity to carcinogens, to oxidative stress, and to chemotherapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

High basal nuclear levels of Nrf2 in acute myeloid leukemia reduces sensitivity to proteasome inhibitors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

High expression of bcl-2 mRNA as a determinant of poor prognosis in acute myeloid leukemia.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Downregulation of microRNA-206 is a potent prognostic marker for patients with gastric cancer

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

MicroRNA-1 inhibits proliferation of hepatocarcinoma cells by targeting endothelin-1.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787145

MicroRNA profiling predicts survival in anti-EGFR treated chemorefractory metastatic colorectal cancer patients with wild-type KRAS and BRAF

3 September 2018

1 reference

12 December 2020

CUL3 and NRF2 mutations confer an NRF2 activation phenotype in a sporadic form of papillary renal cell carcinoma

1 reference

12 December 2020

The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer

1 reference

12 December 2020

The clinical value of hepatocyte growth factor and its receptor--c-met for liver cancer patients with hepatectomy

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.1181

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24029073%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24029073%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24029073%20AND%20SRC:MED&resulttype=core&format=json