(Q37212024)

19 August 2017

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title

Effects of androgens on insulin action in women: is androgen excess a component of female metabolic syndrome? (English)

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19 August 2017

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A Corbould

1

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19 August 2017

1 October 2008

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Diabetes - Metabolism: Research and Reviews

19 August 2017

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19 August 2017

24

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19 August 2017

7

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19 August 2017

520-532

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Inflammation and metabolic disorders

19 August 2017

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7 January 2021

On the paradox of insulin-induced hyperandrogenism in insulin-resistant states

1 reference

7 January 2021

Androgen excess in women--a health hazard?

1 reference

7 January 2021

Hyperandrogenicity in women--a prediabetic condition?

1 reference

7 January 2021

Obesity in adolescent girls: is excess androgen the real bad actor?

1 reference

7 January 2021

Effects of testosterone on fat cell lipolysis. Species differences and possible role in polycystic ovarian syndrome

1 reference

7 January 2021

Obesity and androgens: facts and perspectives

1 reference

7 January 2021

Androgens, insulin resistance and vascular disease in men.

1 reference

7 January 2021

Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis

1 reference

7 January 2021

Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma

1 reference

7 January 2021

Pathophysiology of sex hormone binding globulin (SHBG): relation to insulin

1 reference

7 January 2021

Editorial: Sex hormone binding globulin: inhibitor or facilitator (or both) of sex steroid action?

1 reference

7 January 2021

Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement

1 reference

7 January 2021

Relative androgen excess and increased cardiovascular risk after menopause: a hypothesized relation

1 reference

7 January 2021

Relation of serum levels of sex hormone binding globulin to coronary heart disease in postmenopausal women

1 reference

7 January 2021

Endogenous androgens and carotid intimal-medial thickness in women

1 reference

7 January 2021

Endogenous postmenopausal hormones and carotid atherosclerosis: a case-control study of the atherosclerosis risk in communities cohort

1 reference

7 January 2021

Endogenous sex hormone levels in postmenopausal women undergoing carotid artery endarterectomy

1 reference

7 January 2021

Fasting Plasma Glucose Levels and Endogenous Androgens in Non-Diabetic Postmenopausal Women

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7 January 2021

Association between hyperinsulinemia and endogenous androgen levels in peri- and postmenopausal women.

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7 January 2021

Low sex hormone-binding globulin is associated with the metabolic syndrome in postmenopausal women

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7 January 2021

Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study

1 reference

7 January 2021

Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities study

1 reference

7 January 2021

Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN).

1 reference

7 January 2021

Endogenous sex hormones and glucose tolerance status in postmenopausal women.

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7 January 2021

Testosterone concentrations in women and men with NIDDM.

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7 January 2021

Androgen activity as a risk factor for impaired glucose tolerance in postmenopausal women.

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7 January 2021

Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older men and women

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7 January 2021

Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women

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7 January 2021

Does androgen excess contribute to the cardiovascular risk profile in postmenopausal women with type 2 diabetes?

1 reference

7 January 2021

Low sex-hormone-binding globulin concentration as independent risk factor for development of NIDDM. 12-yr follow-up of population study of women in Gothenburg, Sweden.

1 reference

7 January 2021

Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study

1 reference

7 January 2021

The androgenic sex hormone profile is an essential feature of metabolic syndrome in premenopausal women: a controlled community-based study

1 reference

7 January 2021

The association of obesity and hyperandrogenemia during the pubertal transition in girls: obesity as a potential factor in the genesis of postpubertal hyperandrogenism

1 reference

7 January 2021

Obesity and sex steroid changes across puberty: evidence for marked hyperandrogenemia in pre- and early pubertal obese girls

1 reference

7 January 2021

Effects of testosterone therapy on cardiovascular risk markers in androgen-deficient women with hypopituitarism

1 reference

7 January 2021

Effects of estradiol with and without testosterone on body composition and relationships with lipids in postmenopausal women

1 reference

7 January 2021

Effects of treatment with testosterone alone or in combination with estrogen on insulin sensitivity in postmenopausal women

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7 January 2021

Comparative evaluation of androgen and progesterone receptor transcription selectivity indices of 19-nortestosterone-derived progestins.

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7 January 2021

The effects of different formulations of oral contraceptive agents on lipid and carbohydrate metabolism.

1 reference

7 January 2021

Contraception and the risk of type 2 diabetes mellitus in Latina women with prior gestational diabetes mellitus

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7 January 2021

Androgenicity of progestins in hormonal contraceptives and the risk of gestational diabetes mellitus.

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7 January 2021

The role of the adrenal cortex in polycystic ovary syndrome

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7 January 2021

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS).

1 reference

7 January 2021

Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1 reference

7 January 2021

Phenotypic variation in hyperandrogenic women influences the findings of abnormal metabolic and cardiovascular risk parameters

1 reference

7 January 2021

Characterizing discrete subsets of polycystic ovary syndrome as defined by the Rotterdam criteria: the impact of weight on phenotype and metabolic features

1 reference

7 January 2021

Defects in insulin receptor signaling in vivo in the polycystic ovary syndrome (PCOS).

1 reference

7 January 2021

Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling

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7 January 2021

Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome.

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7 January 2021

Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome

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7 January 2021

Severe impairment of insulin action in adipocytes from amenorrheic subjects with polycystic ovary syndrome

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7 January 2021

The adipose cell lineage is not intrinsically insulin resistant in polycystic ovary syndrome

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7 January 2021

Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease

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7 January 2021

Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance

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7 January 2021

Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome

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7 January 2021

Metabolic profile and body composition in adult women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

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7 January 2021

Suppression of hyperandrogenism does not improve peripheral or hepatic insulin resistance in the polycystic ovary syndrome

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7 January 2021

Insulin sensitivity and antiandrogenic therapy in women with polycystic ovary syndrome

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7 January 2021

No changes of peripheral insulin resistance in polycystic ovary syndrome after long-term reduction of endogenous androgens with leuprolide

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7 January 2021

The effect of a pure antiandrogen receptor blocker, flutamide, on the lipid profile in the polycystic ovary syndrome

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7 January 2021

Effects of two antiandrogen treatments on hirsutism and insulin sensitivity in women with polycystic ovary syndrome.

1 reference

7 January 2021

Effect of two modes of antiandrogen treatment on insulin sensitivity and serum leptin in women with PCOS.

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7 January 2021

Effect of ovarian suppression on glucose metabolism of young lean women with and without ovarian hyperandrogenism.

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7 January 2021

The influence of androgens on insulin resistance.

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7 January 2021

Persistence of insulin resistance in polycystic ovarian disease after inhibition of ovarian steroid secretion.

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7 January 2021

Insulin secretion in polycystic ovarian disease: effect of ovarian suppression by GnRH agonist

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7 January 2021

Hormonal changes in patients with polycystic ovarian disease after ovarian electrocautery or pituitary desensitization

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7 January 2021

Effects of ovary suppression by a long-acting GnRH-agonist on circulating GH, insulin-like growth factor I and insulin levels in women with polycystic ovary syndrome

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7 January 2021

Treatment with flutamide improves hyperinsulinemia in women with idiopathic hirsutism.

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7 January 2021

Metformin versus flutamide in the treatment of metabolic consequences of non-obese young women with polycystic ovary syndrome: a randomized prospective study

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7 January 2021

Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome

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7 January 2021

Spironolactone in the treatment of polycystic ovary syndrome: effects on clinical features, insulin sensitivity and lipid profile.

1 reference

7 January 2021

Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome

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7 January 2021

Treatment with flutamide, metformin, and their combination added to a hypocaloric diet in overweight-obese women with polycystic ovary syndrome: a randomized, 12-month, placebo-controlled study.

1 reference

7 January 2021

Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation

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7 January 2021

Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism

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7 January 2021

Late endocrine effects of ovarian electrocautery in women with polycystic ovary syndrome.

1 reference

7 January 2021

Ovarian electrocauterization causes LH-regulated but not insulin-regulated endocrine changes.

1 reference

7 January 2021

Amelioration of insulin resistance in women with PCOS via reduced insulin receptor substrate-1 Ser312 phosphorylation following laparoscopic ovarian electrocautery.

1 reference

7 January 2021

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

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7 January 2021

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7 January 2021

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

7 January 2021

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

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7 January 2021

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle

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7 January 2021

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

1 reference

7 January 2021

The interconversion and aromatization of androgens by human adipose tissue

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7 January 2021

Influence of adipose tissue distribution on the biological activity of androgens

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7 January 2021

Fat tissue: a steroid reservoir and site of steroid metabolism

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7 January 2021

Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone

1 reference

7 January 2021

Testosterone and Androstenedione Blood Production Rates in Normal Women and Women with Idiopathic Hirsutism or Polycystic Ovaries*

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7 January 2021

Combined Ovarian and Adrenal Vein Catheterization To Determine the Site(s) of Androgen Overproduction in Hirsute Women1

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7 January 2021

A comparison of androgen production and clearance in hirsute and obese women

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7 January 2021

Elevated production and metabolic clearance rates of androgens in morbidly obese women

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7 January 2021

The effect of obesity on the ratio of type 3 17beta-hydroxysteroid dehydrogenase mRNA to cytochrome P450 aromatase mRNA in subcutaneous abdominal and intra-abdominal adipose tissue of women

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7 January 2021

Local androgen inactivation in abdominal visceral adipose tissue.

1 reference

7 January 2021

Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.

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7 January 2021

Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression

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7 January 2021

Identification of steroid receptors in human adipose tissue.

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7 January 2021

Androgen receptors in human preadipocytes and adipocytes: regional specificities and regulation by sex steroids.

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7 January 2021

Intrinsic regional differences in androgen receptors and dihydrotestosterone metabolism in human preadipocytes

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7 January 2021

Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor gamma2

1 reference

7 January 2021

Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors

1 reference

7 January 2021

Effect of testosterone on lipolysis in human pre-adipocytes from different fat depots

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7 January 2021

The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue.

1 reference

7 January 2021

Effects of testosterone and estrogen treatment on lipolysis signaling pathways in subcutaneous adipose tissue of postmenopausal women

1 reference

7 January 2021

Regulation of adenosine 5',monophosphate-activated protein kinase and lipogenesis by androgens contributes to visceral obesity in an estrogen-deficient state.

1 reference

7 January 2021

Effects of prenatal androgenization and lactation on adipose tissue metabolism in finishing single-calf heifers

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7 January 2021

Increased adiposity in female rhesus monkeys exposed to androgen excess during early gestation.

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7 January 2021

Imprinting of female offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats

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7 January 2021

Postnatal testosterone exposure results in insulin resistance, enlarged mesenteric adipocytes, and an atherogenic lipid profile in adult female rats: comparisons with estradiol and dihydrotestosterone.

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7 January 2021

Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?

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7 January 2021

Impairment in insulin sensitivity after early androgenization in the post-pubertal female rat.

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7 January 2021

Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women

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7 January 2021

Effects of testosterone on muscle insulin sensitivity and morphology in female rats.

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7 January 2021

Effects of short-term testosterone exposure on insulin sensitivity of muscles in female rats

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7 January 2021

Insulin insensitivity and delayed transcapillary delivery of insulin in oophorectomized rats treated with testosterone

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7 January 2021

Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment

1 reference

7 January 2021

Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women

1 reference

7 January 2021

Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways

1 reference

7 January 2021

Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse.

1 reference

7 January 2021

Estrogen receptor null mice: what have we learned and where will they lead us?

1 reference

7 January 2021

Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene

1 reference

7 January 2021

Effect of the ovarian hormones on GLUT4 expression and contraction-stimulated glucose uptake

1 reference

7 January 2021

Effect of ovarian hormones on mitochondrial enzyme activity in the fat oxidation pathway of skeletal muscle

1 reference

7 January 2021

Androgen therapy in women: an Endocrine Society Clinical Practice guideline.

1 reference

7 January 2021

Identifiers

DOI

10.1002/DMRR.872

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19 August 2017

1 reference

PubMed ID

18615851