(Q37213606)

English

Toward Smarter Lumping and Smarter Splitting: Rethinking Strategies for Sepsis and Acute Respiratory Distress Syndrome Clinical Trial Design

scientific article published on 31 May 2016

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

Toward Smarter Lumping and Smarter Splitting: Rethinking Strategies for Sepsis and Acute Respiratory Distress Syndrome Clinical Trial Design (English)

1 reference

Europe PubMed Central

19 August 2017

0 references

acute respiratory distress syndrome

1 reference

based on heuristic

inferred from title

4

object named as

Derek C Angus

1 reference

Europe PubMed Central

19 August 2017

2

object named as

Carolyn S Calfee

1 reference

Europe PubMed Central

19 August 2017

author name string

Hallie C Prescott

1

1 reference

Europe PubMed Central

19 August 2017

B Taylor Thompson

3

1 reference

Europe PubMed Central

19 August 2017

Vincent X Liu

5

1 reference

Europe PubMed Central

19 August 2017

language of work or name

0 references

publication date

31 May 2016

1 reference

Europe PubMed Central

19 August 2017

American Journal of Respiratory and Critical Care Medicine

1 reference

Europe PubMed Central

19 August 2017

194

1 reference

Europe PubMed Central

19 August 2017

147-155

1 reference

Europe PubMed Central

19 August 2017

2

1 reference

Europe PubMed Central

19 August 2017

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

1 reference

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6 September 2017

Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries

1 reference

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6 September 2017

Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria

1 reference

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6 September 2017

A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care

1 reference

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6 September 2017

Sepsis: a roadmap for future research

1 reference

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6 September 2017

Trial of Early, Goal-Directed Resuscitation for Septic Shock

1 reference

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6 September 2017

Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial.

1 reference

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6 September 2017

Developing a clinically feasible personalized medicine approach to pediatric septic shock

1 reference

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6 September 2017

Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial

1 reference

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6 September 2017

Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial

1 reference

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6 September 2017

Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials

1 reference

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6 September 2017

The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*.

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6 September 2017

Association between source of infection and hospital mortality in patients who have septic shock

1 reference

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6 September 2017

Systemic inflammatory response syndrome (SIRS): where did it come from and is it still relevant today?

1 reference

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6 September 2017

Two decades of mortality trends among patients with severe sepsis: a comparative meta-analysis*.

1 reference

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6 September 2017

Cost and health care utilization in ARDS--different from other critical illness?

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6 September 2017

Multiplex PCR system for rapid detection of pathogens in patients with presumed sepsis - a systemic review and meta-analysis

1 reference

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6 September 2017

Prone positioning in severe acute respiratory distress syndrome

1 reference

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6 September 2017

Acute respiratory distress syndrome: the Berlin Definition

1 reference

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6 September 2017

Epidemiology of ARDS and ALI.

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6 September 2017

Systemic Steroids in Severe Sepsis and Septic Shock

1 reference

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6 September 2017

Neuromuscular blockers in early acute respiratory distress syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Pharmacological treatments for acute respiratory distress syndrome

1 reference

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6 September 2017

Bayesian statistics in oncology: a guide for the clinical investigator

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6 September 2017

Identification of pediatric septic shock subclasses based on genome-wide expression profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Vasopressin versus norepinephrine infusion in patients with septic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

An expanded definition of the adult respiratory distress syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

6 September 2017

New Strategies for Effective Therapeutics in Critically Ill Patients.

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28 September 2017

Seven Questions for Personalized Medicine

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28 September 2017

Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5003218

28 September 2017

Can overall results of clinical trials be applied to all patients?

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28 September 2017

Trial of the route of early nutritional support in critically ill adults

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26 June 2018

Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012.

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3 September 2018

Comparison of the Berlin definition for acute respiratory distress syndrome with autopsy

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3 September 2018

The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury

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3 September 2018

Problems of stopping trials early

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3 September 2018

Drotrecogin alfa (activated) in adults with septic shock.

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3 September 2018

Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis

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3 September 2018

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3 September 2018

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3 September 2018

Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial.

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3 September 2018

Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation.

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3 September 2018

Effect of prone positioning on the survival of patients with acute respiratory failure.

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3 September 2018

Gene expression profiling: classification of mice with left ventricle systolic dysfunction using microarray analysis

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21 January 2018

Hospital Deaths in Patients With Sepsis From 2 Independent Cohorts

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21 January 2018

Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27244481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between use of lung-protective ventilation with lower tidal volumes and clinical outcomes among patients without acute respiratory distress syndrome: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27244481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticosteroids for Severe Community-Acquired Pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27244481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1164/RCCM.201512-2544CP

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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