(Q37220668)

English

Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons

scientific article published on 13 June 2013

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons. (English)

1 reference

Europe PubMed Central

19 August 2017

amyotrophic lateral sclerosis

0 references

author name string

Leonardo Aliaga

1

1 reference

Europe PubMed Central

19 August 2017

Chen Lai

2

1 reference

Europe PubMed Central

19 August 2017

Jia Yu

3

1 reference

Europe PubMed Central

19 August 2017

Nikolai Chub

4

1 reference

Europe PubMed Central

19 August 2017

Hoon Shim

5

1 reference

Europe PubMed Central

19 August 2017

Lixin Sun

6

1 reference

Europe PubMed Central

19 August 2017

Chengsong Xie

7

1 reference

Europe PubMed Central

19 August 2017

Wan-Jou Yang

8

1 reference

Europe PubMed Central

19 August 2017

Xian Lin

9

1 reference

Europe PubMed Central

19 August 2017

Michael J O'Donovan

10

1 reference

Europe PubMed Central

19 August 2017

Huaibin Cai

11

1 reference

Europe PubMed Central

19 August 2017

publication date

13 June 2013

1 reference

Europe PubMed Central

19 August 2017

Human Molecular Genetics

1 reference

Europe PubMed Central

19 August 2017

22

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Europe PubMed Central

19 August 2017

4293-4305

1 reference

Europe PubMed Central

19 August 2017

21

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Europe PubMed Central

19 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3792689/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Secreted VAPB/ALS8 major sperm protein domains modulate mitochondrial localization and morphology via growth cone guidance receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Accumulation of wildtype and ALS-linked mutated VAPB impairs activity of the proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

The unfolded protein response in familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Excitatory actions of ventral root stimulation during network activity generated by the disinhibited neonatal mouse spinal cord

1 reference

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6 September 2017

The endoplasmic reticulum stress response in immunity and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Molecular development of corticospinal motor neuron circuitry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

The G59S mutation in p150(glued) causes dysfunction of dynactin in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Spinal cholinergic interneurons regulate the excitability of motoneurons during locomotion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Intracellular signaling by the unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Gait analysis detects early changes in transgenic SOD1(G93A) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Large cholinergic nerve terminals on subsets of motoneurons and their relation to muscarinic receptor type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

An electron microscopic examination of the corticospinal projection to the cervical spinal cord in the rat: lack of evidence for cortico-motoneuronal synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

6 September 2017

ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

14 September 2017

VAPB interacts with and modulates the activity of ATF6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

14 September 2017

A cluster of cholinergic premotor interneurons modulates mouse locomotor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

28 September 2017

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

3 September 2018

Structural changes at synapses after delayed perfusion fixation in different regions of the mouse brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

3 September 2018

Expanding the phenotypes of the Pro56Ser VAPB mutation: proximal SMA with dysautonomia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

3 September 2018

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3792689

3 September 2018

Quantitative study of synaptophysin immunoreactivity of cerebral cortex and spinal cord in motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23771029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From ER to Eph receptors: new roles for VAP fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/23771029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/23771029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutation in VAPB that causes amyotrophic lateral sclerosis also causes a nuclear envelope defect

1 reference

https://pubmed.ncbi.nlm.nih.gov/23771029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDT279

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

ResearchGate publication ID

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