(Q37224066)

19 August 2017

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title

Insulin as a physiological modulator of glucagon secretion (English)

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19 August 2017

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1 reference

Pritpal Bansal

1

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19 August 2017

Qinghua Wang

series ordinal

2

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19 August 2017

publication date

22 July 2008

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American Journal of Physiology - Endocrinology and Metabolism

19 August 2017

published in

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19 August 2017

volume

295

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19 August 2017

issue

4

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19 August 2017

page(s)

E751-61

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Cyclic AMP is a hepatorenal link influencing natriuresis and contributing to glucagon-induced hyperfiltration in rats

19 August 2017

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21 January 2018

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Glucagon suppression of ghrelin secretion is exerted at hypothalamus-pituitary level.

21 January 2018

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Electrophysiology of the pancreatic beta-cell

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Endocrine Pancreas: Three-Dimensional Reconstruction Shows Two Types of Islets of Langerhans

21 January 2018

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Glucose-dependent regulation of gamma-aminobutyric acid (GABA A) receptor expression in mouse pancreatic islet alpha-cells.

21 January 2018

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Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response

21 January 2018

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Two SUR1-specific histidine residues mandatory for zinc-induced activation of the rat KATP channel

21 January 2018

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Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

21 January 2018

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Glucagon in physiological concentrations stimulates brown fat thermogenesis in vivo

21 January 2018

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Zinc-induced changes in ionic currents of clonal rat pancreatic -cells: activation of ATP-sensitive K+ channels

21 January 2018

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GABAB receptor: a site of therapeutic benefit

21 January 2018

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Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion.

21 January 2018

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Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

21 January 2018

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Corelease and differential exit via the fusion pore of GABA, serotonin, and ATP from LDCV in rat pancreatic beta cells.

21 January 2018

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Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy

21 January 2018

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Cloning and sequence analysis of the murine glucagon receptor-encoding gene

21 January 2018

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The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

21 January 2018

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Intra-Islet Somatostatin Regulates Glucagon Release via Type 2 Somatostatin Receptors in Rats

21 January 2018

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The 'ABC' of GABA receptors: a brief review

21 January 2018

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Molecular and cellular responses of islets during perturbations of glucose homeostasis determined by in situ hybridization histochemistry

21 January 2018

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Receptor trafficking and synaptic plasticity

21 January 2018

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Glucose-regulated glucagon secretion requires insulin receptor expression in pancreatic alpha-cells

21 January 2018

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The functional significance of sodium channels in pancreatic beta-cell membranes

21 January 2018

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Gamma-aminobutyric acid up- and downregulates insulin secretion from beta cells in concert with changes in glucose concentration

21 January 2018

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The biology of incretin hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulin: new roles for an ancient hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glycine, GABA and their transporters in pancreatic islets of Langerhans: evidence for a paracrine transmitter interplay

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Cellular and subcellular immunolocalization of L-glutamate decarboxylase in rat pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Immunohistochemical colocalization of GABA and insulin in beta-cells of rat islet

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose modulates gamma-aminobutyric acid release from the pancreatic beta TC6 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Normalization of fasting hyperglucagonemia and excessive glucagon responses to intravenous arginine in human diabetes mellitus by prolonged infusion of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

The Influence of γ-Aminobutyric Acid on Hormone Release by the Mouse and Rat Endocrine Pancreas*

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Localization of GAD-like immunoreactivity in the pancreas and stomach of the rat and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Role of the decrement in intraislet insulin for the glucagon response to hypoglycemia in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Intra-islet insulin permits glucose to directly suppress pancreatic A cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Adrenaline stimulates glucagon secretion in pancreatic A-cells by increasing the Ca2+ current and the number of granules close to the L-type Ca2+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Abnormal glucagon response to arginine and its normalization in obese hyperinsulinaemic patients with glucose intolerance: importance of insulin action on pancreatic alpha cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Regulation of alpha-cell function by the beta-cell in isolated human and rat islets deprived of glucose: the "switch-off" hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon receptors on human islet cells contribute to glucose competence of insulin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Effect of intracerebroventricularly infused glucagon on feeding behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon and regulation of glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulin inhibits glucagon secretion by the activation of PI3-kinase in In-R1-G9 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Cellular function in multicellular system for hormone-secretion: electrophysiological aspect of studies on alpha-, beta- and delta-cells of the pancreatic islet

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulin activates ATP-sensitive K(+) channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon stimulates ketone utilization by rat brain slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Modulation of GABAA receptor activity by phosphorylation and receptor trafficking: implications for the efficacy of synaptic inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Decrease in beta-cell mass leads to impaired pulsatile insulin secretion, reduced postprandial hepatic insulin clearance, and relative hyperglucagonemia in the minipig

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Influence of glucagon on natriuresis and glucose-induced sodium retention in the fasting obese subject

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Autometallography allows ultrastructural monitoring of zinc in the endocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

How does a little acronym become a big transmitter?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon and its family revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glutamate inhibits protein phosphatases and promotes insulin exocytosis in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulin regulates islet alpha-cell function by reducing KATP channel sensitivity to adenosine 5'-triphosphate inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Two populations of pancreatic islet alpha-cells displaying distinct Ca2+ channel properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Electrophysiological characterization of pancreatic islet cells in the mouse insulin promoter-green fluorescent protein mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon receptor-mediated extracellular signal-regulated kinase 1/2 phosphorylation in rat mesangial cells: role of protein kinase A and phospholipase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Long-term hyperglucagonaemia induces early metabolic and renal phenotypes of Type 2 diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Functional modulation of the ATP-sensitive potassium channel by extracellular signal-regulated kinase-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulin within islets is a physiologic glucagon release inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagonlike peptide-1(7-36)amide suppresses glucagon secretion and decreases cyclic AMP concentration in cultured In-R1-G9 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

FoxO1 is required for the regulation of preproglucagon gene expression by insulin in pancreatic alphaTC1-9 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Functional subdivision of islets of Langerhans and possible role of D cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glycemic control in mice with targeted disruption of the glucagon receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Islet-specific proteins interact with the insulin-response element of the glucagon gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Zinc is both an intracellular and extracellular regulator of KATP channel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Loss of the decrement in intraislet insulin plausibly explains loss of the glucagon response to hypoglycemia in insulin-deficient diabetes: documentation of the intraislet insulin hypothesis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Effect of Intermittent Endogenous Hyperglucagonemia on Glucose Homeostasis in Normal and Diabetic Man

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Voltage-activated currents in guinea pig pancreatic alpha 2 cells. Evidence for Ca2+-dependent action potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Paradoxical stimulation of glucagon secretion by high glucose concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

The order of islet microvascular cellular perfusion is B----A----D in the perfused rat pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Protein kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon-induced somatostatin release from perifused rat hypothalamus: calcium dependency and effect of cysteamine treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose-stimulated signaling pathways in biphasic insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Critical nodes in signalling pathways: insights into insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

High Concentration of Gamma-Aminobutyric Acid in Pancreatic Beta Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Possible role of alpha-cell insulin resistance in exaggerated glucagon responses to arginine in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Metabotropic glutamate receptor type 4 is involved in autoinhibitory cascade for glucagon secretion by alpha-cells of islet of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Role of glucagon in the pathogenesis of diabetes: The status of the controversy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucagon physiology and pathophysiology in the light of new advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Studies of pancreatic alpha cell function in normal and diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Physiology and pathophysiology of glucagon

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

GABAA receptor-associated phosphoinositide 3-kinase is required for insulin-induced recruitment of postsynaptic GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Characterization of voltage-dependent sodium and calcium channels in mouse pancreatic A- and B-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose inhibits GABA release by pancreatic beta-cells through an increase in GABA shunt activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Control of synaptic strength, a novel function of Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Molecular and functional diversity of the expanding GABA-A receptor gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Correlation between GABA release from rat islet beta-cells and their metabolic state

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Targeting of voltage-gated K+ and Ca2+ channels and soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins to cholesterol-rich lipid rafts in pancreatic alpha-cells: effects on glucagon stimulus-secretion coupling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

Regulation of alpha-cell function by the beta-cell during hypoglycemia in Wistar rats: the "switch-off" hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.90295.2008

10.1152/AJPENDO.90295.2008

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference