(Q40482231)

20 September 2017

Protein kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription. (English)

1 reference

20 September 2017

1 reference

1 reference

5

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20 September 2017

Sven Schinner

1

1 reference

20 September 2017

Andreas Barthel

2

1 reference

20 September 2017

Claudia Dellas

3

1 reference

20 September 2017

Rafal Grzeskowiak

4

1 reference

20 September 2017

Elke Oetjen

6

1 reference

20 September 2017

Roland Blume

7

1 reference

20 September 2017

Willhart Knepel

8

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20 September 2017

language of work or name

English

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publication date

7 December 2004

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

8

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20 September 2017

7369-7376

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Glucagon and its family revisited

20 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Glucagon and the A cell: physiology and pathophysiology (first two parts).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin responsiveness of the glucagon gene conferred by interactions between proximal promoter and more distal enhancer-like elements involving the paired-domain transcription factor Pax6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Repression of glucagon gene transcription by peroxisome proliferator-activated receptor gamma through inhibition of Pax6 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Transcriptional regulation of plasminogen activator inhibitor type 1 gene by insulin: insights into the signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Dominant negative forms of Akt (protein kinase B) and atypical protein kinase Clambda do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Phosphatidylinositol 3-kinase and Ras/mitogen-activated protein kinase signaling pathways are required for the regulation of 5-aminolevulinate synthase gene expression by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Role of Akt/protein kinase B in metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Assessment of the roles of mitogen-activated protein kinase, phosphatidylinositol 3-kinase, protein kinase B, and protein kinase C in insulin inhibition of cAMP-induced phosphoenolpyruvate carboxykinase gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

A family with severe insulin resistance and diabetes due to a mutation in AKT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Long-distance transcriptional enhancement by the histone acetyltransferase PCAF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Involvement of the Ca(2+)-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Characterization of a novel protein kinase C response element in the glucagon gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Characterization of a novel calcium response element in the glucagon gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Mechanism of activation and function of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

21 January 2018

Glucagon-like peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Blood glucose lowering and glucagonostatic effects of glucagon-like peptide I in insulin-deprived diabetic dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

A tripartite array of transcription factor binding sites mediates cAMP induction of phosphoenolpyruvate carboxykinase gene transcription and its inhibition by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

CREB binding protein coordinates the function of multiple transcription factors including nuclear factor I to regulate phosphoenolpyruvate carboxykinase (GTP) gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin inhibition of glucocorticoid-stimulated gene transcription: requirement for an insulin response element?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408560200

21 January 2018

Identifiers

DOI

10.1074/JBC.M408560200

1 reference

20 September 2017

1 reference