(Q37226580)

19 August 2017

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title

Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives (English)

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19 August 2017

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Sally A. Madsen-Bouterse

object named as

Sally A Madsen-Bouterse

series ordinal

1

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author name string

Renu A Kowluru

series ordinal

2

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19 August 2017

1 December 2008

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Reviews in Endocrine and Metabolic Disorders

19 August 2017

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19 August 2017

9

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19 August 2017

4

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19 August 2017

315-327

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https://scigraph.springernature.com/pub.10.1007/s11154-008-9090-4

19 August 2017

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Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro

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Nitric oxide and peroxynitrite interactions with mitochondria

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Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes

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The reaction of no with superoxide

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Retinal vascular changes induced by the oxidative stress of alpha-tocopherol deficiency contrasted with diabetic microangiopathy

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Cellular signaling and potential new treatment targets in diabetic retinopathy

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PARP activation and the alteration of vasoactive factors and extracellular matrix protein in retina and kidney in diabetes.

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Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin

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12 December 2020

Aldose reductase inhibition prevents glucose-induced apoptosis in cultured bovine retinal microvascular pericytes

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12 December 2020

Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy

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The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c

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12 December 2020

The impact of diabetic retinopathy on health-related quality of life

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12 December 2020

Antioxidants and an inhibitor of advanced glycation ameliorate death of retinal microvascular cells in diabetic retinopathy

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12 December 2020

A Novel CRM1-mediated Nuclear Export Signal Governs Nuclear Accumulation of Glyceraldehyde-3-phosphate Dehydrogenase following Genotoxic Stress

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Effect of long-term administration of alpha-lipoic acid on retinal capillary cell death and the development of retinopathy in diabetic rats

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Clinical review: The role of advanced glycation end products in progression and complications of diabetes

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Relations of serum ascorbic acid and alpha-tocopherol to diabetic retinopathy in the Third National Health and Nutrition Examination Survey

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The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes

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Economic costs of diabetes in the U.S. In 2007.

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Effects of curcumin on retinal oxidative stress and inflammation in diabetes

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Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress

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Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase

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Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats

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S-nitrosoglutathione reversibly inhibits GAPDH by S-nitrosylation

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Anti-diabetic activity of green tea polyphenols and their role in reducing oxidative stress in experimental diabetes

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Diabetes-induced activation of caspase-3 in retina: effect of antioxidant therapy

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Relation between intake of vitamins C and E and risk of diabetic retinopathy in the Atherosclerosis Risk in Communities Study

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Hyperglycemia as a cause of diabetic retinopathy

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Screening for subclinical complications in young type 1 diabetic patients: experience acquired in Brussels.

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Altered mRNA levels of antioxidant enzymes in pre-apoptotic pericytes from human diabetic retinas

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12 December 2020

New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells

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12 December 2020

Involvement of gangliosides in glucosamine-induced proliferation decrease of retinal pericytes.

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12 December 2020

A central role for inflammation in the pathogenesis of diabetic retinopathy

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Complementary therapies for diabetes: the case for chromium, magnesium, and antioxidants

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12 December 2020

Lipid peroxidation and retinopathy in streptozotocin-induced diabetes

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Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine

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Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy

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Inducible nitric oxide synthase mediates retinal apoptosis in ischemic proliferative retinopathy.

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12 December 2020

Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia

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12 December 2020

alpha-lipoic acid corrects late-phase supernormal retinal oxygenation response in experimental diabetic retinopathy

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12 December 2020

The pathobiology of diabetic complications: a unifying mechanism

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Inhibition of advanced glycation end‐products protects against retinal capillary basement membrane expansion during long‐term diabetes

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12 December 2020

Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy

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12 December 2020

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12 December 2020

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12 December 2020

Regulation of retinal hemodynamics in diabetic rats by increased expression and action of endothelin-1.

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12 December 2020

Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons

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12 December 2020

Role of interleukin-1beta in the pathogenesis of diabetic retinopathy

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12 December 2020

Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells

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12 December 2020

Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy

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12 December 2020

Beneficial effect of zeaxanthin on retinal metabolic abnormalities in diabetic rats

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12 December 2020

Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are interrelated

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12 December 2020

Analysis of glucose metabolism in diabetic rat retinas

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12 December 2020

Role of vascular endothelial growth factor in diabetic vascular complications

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12 December 2020

Immunological mechanisms in the pathogenesis of diabetic retinopathy

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12 December 2020

Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats

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12 December 2020

Modulation of activator protein-1 (AP-1) transcription factor and protein kinase C by hydrogen peroxide and D-alpha-tocopherol in vascular smooth muscle cells

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12 December 2020

Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor

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12 December 2020

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

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12 December 2020

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

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12 December 2020

Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia

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12 December 2020

Oxidative stress in the pathogenesis of diabetic neuropathy

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12 December 2020

Aldose reductase inhibitors: therapeutic implications for diabetic complications

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12 December 2020

New Insights on Oxidative Stress and Diabetic Complications May Lead to a “Causal” Antioxidant Therapy

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12 December 2020

Natural history of cardiovascular disease in patients with diabetes: role of hyperglycemia

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12 December 2020

Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin

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12 December 2020

Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Müller cells

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12 December 2020

Fas mediated apoptosis of human Jurkat T-cells: intracellular events and potentiation by redox-active alpha-lipoic acid

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12 December 2020

Substrates modified by advanced glycation end-products cause dysfunction and death in retinal pericytes by reducing survival signals mediated by platelet-derived growth factor.

1 reference

12 December 2020

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

1 reference

12 December 2020

Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia

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12 December 2020

Paradoxical effects of green tea (Camellia sinensis) and antioxidant vitamins in diabetic rats: improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking

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12 December 2020

Proteomic identification of 3-nitrotyrosine-containing rat cardiac proteins: effects of biological aging

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12 December 2020

Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation

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12 December 2020

Protein kinase C signaling and oxidative stress

1 reference

12 December 2020

Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress

1 reference

12 December 2020

Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kappaB) in the retina.

1 reference

12 December 2020

Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.

1 reference

12 December 2020

A randomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy. Sorbinil Retinopathy Trial Research Group

1 reference

12 December 2020

High glucose can induce lipid peroxidation in the isolated rat glomeruli

1 reference

12 December 2020

Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy

1 reference

12 December 2020

Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death

1 reference

12 December 2020

The eye in hypertension

1 reference

12 December 2020

Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells

1 reference

12 December 2020

Oxidative stress and diabetic retinopathy

1 reference

12 December 2020

The role of advanced glycation in the pathogenesis of diabetic retinopathy.

1 reference

12 December 2020

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

1 reference

12 December 2020

Inhibition of retinopathy and retinal metabolic abnormalities in diabetic rats with AREDS-based micronutrients

1 reference

12 December 2020

Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy

1 reference

12 December 2020

Long-term treatment with fidarestat suppresses the development of diabetic retinopathy in STZ-induced diabetic rats

1 reference

12 December 2020

Role of interleukin-1beta in the development of retinopathy in rats: effect of antioxidants

1 reference

12 December 2020

Abnormalities of retinal metabolism in diabetes or experimental galactosemia. IV. Antioxidant defense system.

1 reference

12 December 2020

Interaction of Endothelin-1 with Vasoactive Factors in Mediating Glucose-Induced Increased Permeability in Endothelial Cells

1 reference

12 December 2020

Reversible post-translational modification of proteins by nitrated fatty acids in vivo

1 reference

12 December 2020

Pro-oxidant role of heme oxygenase in mediating glucose-induced endothelial cell damage.

1 reference

12 December 2020

1 reference

12 December 2020

Diabetes-induced mitochondrial dysfunction in the retina

1 reference

12 December 2020

Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy

1 reference

12 December 2020

Effect of advanced glycation end products on accelerated apoptosis of retinal capillary cells under in vitro conditions

1 reference

12 December 2020

Subcellular distribution of glyceraldehyde-3-phosphate dehydrogenase in cerebellar granule cells undergoing cytosine arabinoside-induced apoptosis.

1 reference

12 December 2020

Superoxide production from nonenzymatically glycated protein

1 reference

12 December 2020

Healthy coping, negative emotions, and diabetes management: a systematic review and appraisal

1 reference

12 December 2020

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm

1 reference

12 December 2020

Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death

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12 December 2020

Does pregnancy accelerate the rate of progression of diabetic retinopathy?

1 reference

12 December 2020

Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes

1 reference

12 December 2020

Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase

1 reference

12 December 2020

Reaction of NO with O2-. implications for the action of endothelium-derived relaxing factor (EDRF)

1 reference

12 December 2020

Aminoguanidine treatment inhibits the development of experimental diabetic retinopathy

1 reference

12 December 2020

Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats

1 reference

12 December 2020

The Relationship of Dietary Lipid Intake and Age-Related Macular Degeneration in a Case-Control Study

1 reference

12 December 2020

Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB.

1 reference

12 December 2020

A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy.

1 reference

12 December 2020

Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases.

1 reference

12 December 2020

Regulation of tight junctions and loss of barrier function in pathophysiology

1 reference

12 December 2020

Early cellular and molecular changes induced by diabetes in the retina

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12 December 2020

Oxidative stress in diabetes

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12 December 2020

Potential contributory role of H-Ras, a small G-protein, in the development of retinopathy in diabetic rats

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12 December 2020

Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients

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12 December 2020

High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase

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12 December 2020

Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes

1 reference

12 December 2020

Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants.

1 reference

12 December 2020

What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?

1 reference

12 December 2020

PKCbetaII/HuR/VEGF: A new molecular cascade in retinal pericytes for the regulation of VEGF gene expression

1 reference

12 December 2020

10.1007/S11154-008-9090-4

Identifiers

DOI

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19 August 2017

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PubMed ID

18654858