(Q37242594)

English

Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies

scientific article published on January 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

1 reference

Europe PubMed Central

Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

1 reference

based on heuristic

inferred from title

0 references

nicotine dependence

1 reference

based on heuristic

inferred from title

author name string

Matthias E Liechti

1

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

Athina Markou

2

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

publication date

1 January 2008

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

705-724

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

https://scigraph.springernature.com/pub.10.2165/00023210-200822090-00001

0 references

Behavioural and neurochemical adaptations to nicotine in rats: influence of NMDA antagonists

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200822090-00001

21 January 2018

MK801 attenuates behavioural adaptation to chronic nicotine administration in rats

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200822090-00001

21 January 2018

Acamprosate enhances N-methyl-D-apartate receptor-mediated neurotransmission but inhibits presynaptic GABA(B) receptors in nucleus accumbens neurons

1 reference

https://api.crossref.org/works/10.2165%2F00023210-200822090-00001

21 January 2018

The novel mGluR2/3 agonist LY379268 attenuates cue-induced reinstatement of heroin seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamatergic substrates of drug addiction and alcoholism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine produces modest reductions in heroin-induced subjective responses in human research volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of topiramate on cue-induced cigarette craving and the response to a smoked cigarette in briefly abstinent smokers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenyl-tetrazolyl acetophenones: discovery of positive allosteric potentiatiors for the metabotropic glutamate 2 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The selective mGlu2/3 receptor antagonist LY341495 exacerbates behavioral signs of morphine withdrawal and morphine-withdrawal-induced activation of locus coeruleus neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rodent model of nicotine abstinence syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effectiveness of smoking cessation therapies: a systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine-induced excitation of midbrain dopamine neurons in vitro involves ionotropic glutamate receptor activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dramatic decreases in brain reward function during nicotine withdrawal.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term potentiation of excitatory inputs to brain reward areas by nicotine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary evidence for gender-specific effects of topiramate as a potential aid to smoking cessation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of abstinence from tobacco: valid symptoms and time course

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reinstatement model of drug relapse: history, methodology and major findings

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate II receptor agonists in panic disorder: a double blind clinical trial with LY354740.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A metabotropic glutamate 2/3 receptor antagonist, MGS0039, increases extracellular dopamine levels in the nucleus accumbens shell.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine fails to facilitate partial cigarette deprivation in smokers – no role of Memantine in the treatment of nicotine dependency?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-administration in alcohol-preferring (P) rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple brain pathways and receptors underlying tobacco addiction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGluR2/3 agonist LY379268 attenuates context- and discrete cue-induced reinstatement of sucrose seeking but not sucrose self-administration in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The scientific case that nicotine is addictive.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine-induced dopamine release in the nucleus accumbens is inhibited by the novel AMPA antagonist ZK200775 and the NMDA antagonist CGP39551.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The selective mGlu2/3 receptor agonist LY354740 attenuates morphine-withdrawal-induced activation of locus coeruleus neurons and behavioral signs of morphine withdrawal

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

d-Cycloserine facilitates extinction of a cocaine-induced conditioned place preference.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor antagonists: novel therapeutics for nicotine dependence and depression?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphine tolerance and reward but not expression of morphine dependence are inhibited by the selective glutamate carboxypeptidase II (GCP II, NAALADase) inhibitor, 2-PMPA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of acute pretreatment with high-dose memantine on the cardiovascular and behavioral effects of cocaine in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine self-administration acutely activates brain reward systems and induces a long-lasting increase in reward sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain nicotinic acetylcholine receptors: native subtypes and their relevance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal systems underlying behaviors related to nicotine addiction: neural circuits and molecular genetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basolateral amygdala stimulation evokes glutamate receptor-dependent dopamine efflux in the nucleus accumbens of the anaesthetized rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral topiramate for treatment of alcohol dependence: a randomised controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate 2/3 receptor activation induced reward deficits but did not aggravate brain reward deficits associated with spontaneous nicotine withdrawal in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate synaptic inputs to ventral tegmental area neurons in the rat derive primarily from subcortical sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated administration of the GABAB receptor agonist CGP44532 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine-seeking in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Damage to the insula disrupts addiction to cigarette smoking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurochemical changes of the extracellular concentrations of glutamate and aspartate in the nucleus accumbens of rats after chronic administration of morphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective dopamine antagonists reduce nicotine self-administration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NR2B-selective N-methyl-D-aspartate receptor antagonist Ro 25-6981 [(+/-)-(R*,S*)-alpha-(4-hydroxyphenyl)-beta-methyl-4-(phenylmethyl)-1-piperidine propanol] potentiates the effect of nicotine on locomotor activity and dopamine release in the nu

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of oral topiramate to promote smoking abstinence among alcohol-dependent smokers: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of behavioral sensitization to cocaine by NAALADase inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measuring nicotinic receptors with characteristics of alpha4beta2, alpha3beta2 and alpha3beta4 subtypes in rat tissues by autoradiography

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionotropic and metabotropic glutamate receptor structure and pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neurotransmitter release by metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic receptors modulate transmitter cross talk in the CNS: nicotinic modulation of transmitters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic nicotinic ACh receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reinstatement of nicotine-seeking behavior by drug-associated stimuli after extinction in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is cocaine desire reduced by N-acetylcysteine?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cue dependency of nicotine self-administration and smoking.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biphasic effect of acamprosate on NMDA but not on GABAA receptors in spontaneous rhythmic activity from the isolated neonatal rat respiratory network.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamatergic antagonists attenuate ability of dopamine uptake blockers to increase extracellular levels of dopamine: implications for tonic influence of glutamate on dopamine release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pilot trial of topiramate for the treatment of cocaine dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mecamylamine attenuates cue-induced reinstatement of nicotine-seeking behavior in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic potential of NMDA receptor antagonists in the treatment of alcohol and substance use disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved bioavailability of the mGlu2/3 receptor agonist LY354740 using a prodrug strategy: in vivo pharmacology of LY544344.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioural and biochemical adaptations to nicotine in rats: influence of MK801, an NMDA receptor antagonist.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nicotinic and NMDA receptor channel blockers on intravenous cocaine and nicotine self-administration in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate and depression: clinical and preclinical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine activates and desensitizes midbrain dopamine neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for AMPA receptors in mood disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of ionotropic glutamate receptor subunits within specific mesocorticolimbic regions during chronic nicotine self-administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for Homer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl)pyrid-3-ylmethylamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous nicotine withdrawal potentiates the effects of stress in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of memantine on the subjective, reinforcing and cardiovascular effects of cocaine in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of antidepressant potency by a potentiator of AMPA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An open-label trial of N-acetylcysteine for the treatment of cocaine dependence: a pilot study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reinstatement of nicotine self-administration in rats by presentation of nicotine-paired stimuli, but not nicotine priming

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamatergic afferents of the ventral tegmental area in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and food-seeking behavior in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for conditioned ventral tegmental glutamate release in cocaine seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropharmacology and potential efficacy of new treatments for tobacco dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptors in the therapeutic management of depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabotropic glutamate receptors: structure and functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of abstinence from tobacco: etiology, animal models, epidemiology, and significance: a subjective review

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociating nicotine and nonnicotine components of cigarette smoking.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine self-administration in animals as a dependence model

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine in moderate-to-severe Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a metabotropic glutamate(2/3) receptor agonist (LY544344/LY354740) on panic anxiety induced by cholecystokinin tetrapeptide in healthy humans: preliminary results

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nicotine and mecamylamine-induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotransmitter regulation of dopamine neurons in the ventral tegmental area

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pilot double-blind treatment trial of memantine for alcohol dependence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological stimulation of group ii metabotropic glutamate receptors reduces cocaine self-administration and cocaine-induced reinstatement of drug seeking in squirrel monkeys.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ups and downs of addiction: role of metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topiramate selectively attenuates nicotine-induced increases in monoamine release

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-acetyl cysteine-induced blockade of cocaine-induced reinstatement

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Putative role of presynaptic alpha7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and acquisition of the conditioned place preference response to cocaine in rats is blocked by selective inhibitors of the enzyme N-acetylated-alpha-linked-acidic dipeptidase (NAALADASE).

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of sustained-release bupropion and placebo for smoking cessation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and tolerability of an mGlu2/3 agonist in the treatment of generalized anxiety disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seeking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective blockade of drug-induced place preference conditioning by ACPC, a functional NDMA-receptor antagonist.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate receptor subtypes: promising new pharmacotherapeutic targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiology of cocaine addiction: implications for new pharmacotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topiramate in opiate withdrawal- comparison with clonidine and with carbamazepine/mianserin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of NMDA glutamate receptor antagonist drugs on the volitional consumption of ethanol by a genetic drinking rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine self-administration in animals and humans: similarities and differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine increases cardiovascular but not behavioral effects of cocaine in methadone-maintained humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topiramate for smoking cessation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociating the primary reinforcing and reinforcement-enhancing effects of nicotine using a rat self-administration paradigm with concurrently available drug and environmental reinforcers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LY354740, an mGlu2/3 receptor agonist as a novel approach to treat anxiety/stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of topiramate in combination with intravenous nicotine in overnight abstinent smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic nicotine stimulates dopamine release in nucleus accumbens: re-evaluation of the role of N-methyl-D-aspartate receptors in the ventral tegmental area

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18698872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00023210-200822090-00001

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 August 2017

Sitelinks

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