(Q34415261)

2 August 2017

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title

Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy. (English)

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2 August 2017

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1

Kornhuber J

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2 August 2017

2

M Weller

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PubMed ID

9018383

2 August 2017

language of work or name

English

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publication date

1 January 1997

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2 August 2017

Biological Psychiatry

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2 August 2017

41

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2 August 2017

135-144

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2 August 2017

2

1 reference

Intra- and extracellular changes of amino acids in the cerebral cortex of the neonatal rat during hypoxic-ischemia.

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Long-term neuropathological and neurochemical effects of nucleus basalis lesions in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

A synaptic model of memory: long-term potentiation in the hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Memantine is a potent blocker of N-methyl-D-aspartate (NMDA) receptor channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The glial cell glutamate uptake carrier countertransports pH-changing anions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Different binding affinities of NMDA receptor channel blockers in various brain regions—Indication of NMDA receptor heterogeneity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The time course of glutamate in the synaptic cleft

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Comparison of phencyclidine hydrochloride (Sernyl) with other drugs. Simulation of schizophrenic performance with phencyclidine hydrochloride (Sernyl), lysergic acid diethylamide (LSD-25), and amobarbital (Amytal) sodium; II. Symbolic and sequential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Simple and rapid GLC method for the determination of orphenadrine in human plasma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Controlled induction of paired helical filaments of the Alzheimer type in cultured human neurons, by glutamate and aspartate.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Alterations in L-glutamate binding in Alzheimer's and Huntington's diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Glutamate transmission and toxicity in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The antiparkinsonian drugs budipine and biperiden are use-dependent (uncompetitive) NMDA receptor antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Antagonist drug selectivity for radioligand binding sites on voltage-gated and N-methyl-D-aspartate receptor-gated Ca2+ channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Recent advances in the phencyclidine model of schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The antiparkinsonian agent budipine is an N-methyl-D-aspartate antagonist.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Memantine displaces [3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

[3H]MK-801 binding sites in post-mortem human frontal cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Affinity of 1-aminoadamantanes for the σ binding site in post-mortem human frontal cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Therapeutic brain concentration of the NMDA receptor antagonist amantadine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Cerebrospinal fluid and serum concentrations of the N-methyl-D-aspartate (NMDA) receptor antagonist memantine in man.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Amantadine and the glutamate hypothesis of schizophrenia Experiences in the treatment of neuroleptic malignant syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Amantadine versus biperiden: a double-blind study of treatment efficacy in neuroleptic extrapyramidal movement disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Molecular diversity of the NMDA receptor channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Difference between single and multiple dose pharmacokinetics of orphenadrine hydrochloride in man.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The toxic effect of sodium L-glutamate on the inner layers of the retina.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Molecular diversity of glutamate receptors and implications for brain function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Controlled trial of amantadine hydrochloride in Parkinson's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The relationship between antidepressant response and tricyclic antidepressant plasma concentrations. A retrospective analysis of the literature using logistic regression analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Comparison of sernyl with other drugs: simulation of schizophrenic performance with sernyl, LSD-25, and amobarbital (amytal) sodium; I. Attention, motor function, and proprioception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or intranigral 1-methyl-4-phenylpyridinium in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Immunohistochemical evidence for apoptosis in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

NMDA receptor-mediated glutamate toxicity of cultured cerebellar, cortical and mesencephalic neurons: neuroprotective properties of amantadine and memantine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

MK-801 and memantine protect cultured neurons from glutamate toxicity induced by glutamate carboxypeptidase-mediated cleavage of methotrexate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

3-Nitropropionic acid is an indirect excitotoxin to cultured cerebellar granule neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

Pharmacokinetics and Pharmacodynamics of procyclidine in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2896%2900047-9

10.1016/S0006-3223(96)00047-9

7 January 2021

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

9018383