(Q37246148)

19 August 2017

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title

Gene-nutrient interactions: importance of folic acid and vitamin B12 during early embryogenesis (English)

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19 August 2017

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2

Gary M Shaw

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19 August 2017

Richard H Finnell

1

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19 August 2017

Edward J Lammer

series ordinal

3

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19 August 2017

Thomas H Rosenquist

series ordinal

4

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19 August 2017

publication date

1 June 2008

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Food and Nutrition Bulletin

19 August 2017

published in

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19 August 2017

volume

29

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19 August 2017

issue

2 Suppl

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19 August 2017

page(s)

S86-98; discussion S99-100

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Child health statistical review, 1997

19 August 2017

cites work

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Socioeconomic inequalities in risk of congenital anomaly

21 January 2018

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Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development

21 January 2018

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Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation.

21 January 2018

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Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal hyperhomocysteinemia: a risk factor for neural-tube defects?

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Periconceptional vitamin use, dietary folate, and the occurrence of neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Risk of neural tube defect-affected pregnancies among obese women

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip.

21 January 2018

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Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Quantifying the effect of folic acid

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Neural tube and craniofacial defects with special emphasis on folate pathway genes.

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Lack of association between mutations in the folate receptor-alpha gene and spina bifida

21 January 2018

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https://api.crossref.org/works/10.1177%2F15648265080292S112

Folate pathway gene alterations in patients with neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Reduced folate carrier polymorphism (80A-->G) and neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Smoking, genetic polymorphisms in biotransformation enzymes, and nonsyndromic oral clefting: a gene-environment interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Genetic variation analysis of MLP, TFAP2A, and CSK in patients with neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Periconceptional use of multivitamins and the occurrence of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Periconceptional folic acid exposure and risk of occurrent neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Review of neural tube defects: risk factors in parental occupation and the environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal supplemental and dietary zinc intake and the occurrence of neural tube defects in California

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Folic acid antagonists during pregnancy and the risk of birth defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Neural tube defects among Mexican Americans living on the US-Mexico border: effects of folic acid and dietary folate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Folic acid alone prevents neural tube defects: evidence from the China study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Dieting behaviors and risk of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Mouse models for neural tube closure defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Neural tube defects and folate: case far from closed

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Investigations into the etiology of neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Neurulation in the cranial region--normal and abnormal

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

A log-linear approach to case-parent-triad data: assessing effects of disease genes that act either directly or through maternal effects and that may be subject to parental imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Studying parents and grandparents to assess genetic contributions to early-onset disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Susceptibility to spina bifida; an association study of five candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Molecular genetic analysis of the gene encoding the trifunctional enzyme MTHFD (methylenetetrahydrofolate-dehydrogenase, methenyltetrahydrofolate-cyclohydrolase, formyltetrahydrofolate synthetase) in patients with neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Structural and Functional Analysis of the Human KB Cell Folate Receptor Gene P4 Promoter: Cooperation of Three Clustered Sp1-Binding Sites with Initiator Region for Basal Promoter Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Folate levels and N(5),N(10)-methylenetetrahydrofolate reductase genotype (MTHFR) in mothers of offspring with neural tube defects: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Mouse models of neural tube defects: investigating preventive mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Integration of DNA sample collection into a multi-site birth defects case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

A review of folate receptor alpha cycling and 5-methyltetrahydrofolate accumulation with an emphasis on cell models in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Folate receptor endocytosis and trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Endocytosis of GPI-linked membrane folate receptor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Spatial and temporal expression of folate-binding protein 1 (Fbp1) is closely associated with anterior neural tube closure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Developmental consequences of abnormal folate transport during murine heart morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Novel insertion and deletion mutations in the 5'-UTR of the folate receptor-alpha gene: an additional contributor to hyperhomocysteinemia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

A test for linkage and association in general pedigrees: the pedigree disequilibrium test

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Homocysteine induces congenital defects of the heart and neural tube: effect of folic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Neural-tube defects and derangement of homocysteine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Enhanced reduction of fasting total homocysteine levels with supraphysiological versus standard multivitamin dose folic acid supplementation in renal transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Altered vitamin B12 metabolism in fibroblasts from a patient with megaloblastic anemia and homocystinuria due to a new defect in methionine biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Prevention of congenital abnormalities by periconceptional multivitamin supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Dietary folate and nonneural midline birth defects: no evidence of an association from a case-control study in Western Australia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Association between 5,10-Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Conotruncal Heart Defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Essential nature of choline with implications for total parenteral nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Primary prevention of neural tube defects with folic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Cardiac outflow tract malformations in chick embryos exposed to homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Homocysteine metabolism in pregnancies complicated by neural-tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Elevated midtrimester serum methylmalonic acid levels as a risk factor for neural tube defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Congenital heart defects and maternal derangement of homocysteine metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Vitamin B12 insufficiency and the risk of fetal neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal serum folate and vitamin B12 concentrations in pregnancies associated with neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal vitamin levels during pregnancies producing infants with neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Marginal maternal vitamin B12 status increases the risk of offspring with spina bifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Nutrient Levels in Amniotic Fluid from Women with Normal and Neural Tube Defect Pregnancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal Stress, Social Support, and Risk of Neural Tube Defects Among Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal serum B12 levels and risk for neural tube defects in a Texas-Mexico border population

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Transcobalamin and methionine synthase reductase mutated polymorphisms aggravate the risk of neural tube defects in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Maternal folate status and the risk for neural tube defects. The role of dietary folate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

The methylfolate axis in neural tube defects: in vitro characterisation and clinical investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Genetic variants inZIC1,ZIC2, andZIC3 are not major risk factors for neural tube defects in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Distinguishing the Effects of Maternal and Offspring Genes through Studies of "Case-Parent Triads"

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

Methionine Synthase: High-Resolution Mapping of the Human Gene and Evaluation as a Candidate Locus for Neural Tube Defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15648265080292S112

10.1177/15648265080292S112

21 January 2018

Identifiers

DOI

0 references

1 reference