(Q37262001)

English

Bama miniature pigs (Sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin

scientific article published on December 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Bama miniature pigs (Sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

0 references

0 references

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Yu Liu

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Ben-Hua Zeng

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Hai-Tao Shang

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yan-Yan Cen

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Hong Wei

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

1 December 2008

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Comparative Medicine

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

58

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

580-587

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Cytochromes P450 and experimental models of drug metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Microsomal catalyzed N-hydroxylation of guanabenz and reduction of the N-hydroxylated metabolite: characterization of the two reactions and genotoxic potential of guanoxabenz

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Species differences in metabolism and pharmacokinetics: are we close to an understanding?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

6 September 2017

Human, rat and crocodile liver microsomal monooxygenase activities measured using diazepam and nifedipine: effects of CYP3A inhibitors and relationship to immunochemically detected CYP3A apoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

26 June 2018

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

26 June 2018

Metabolism of lovastatin by rat and human liver microsomes in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

26 June 2018

A Consumer Use Study of Over-The-Counter lovastatin (CUSTOM).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

3 September 2018

A multicenter, randomized, double-blind clinical trial comparing the low-density lipoprotein cholesterol-lowering ability of lovastatin 10, 20, and 40 mg/d with fluvastatin 20 and 40 mg/d

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

3 September 2018

[Analysis of genetic diversity of Bama miniature pigs and Guizhou miniature pigs by RAPD]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

3 September 2018

Inhalation studies with the Göttingen minipig

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

3 September 2018

Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

3 September 2018

Biotransformation of lovastatin. V. Species differences in in vivo metabolite profiles of mouse, rat, dog, and human.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2710758

3 September 2018

Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/19149415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The physiological disposition of lovastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19149415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biotransformation of lovastatin. I. Structure elucidation of in vitro and in vivo metabolites in the rat and mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/19149415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biotransformation of lovastatin. IV. Identification of cytochrome P450 3A proteins as the major enzymes responsible for the oxidative metabolism of lovastatin in rat and human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19149415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of NO-1886 on inflammation-associated cytokines in high-fat/high-sucrose/high-cholesterol diet-fed miniature pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19149415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19149415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The minipig in toxicology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19149415

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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