(Q37267062)

English

Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance

scientific article published on 02 June 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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1 reference

based on heuristic

inferred from title

6

object named as

Graeme I Bell

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Dennis T. Villareal

1

object named as

Dennis T Villareal

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Joseph C Koster

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Heather Robertson

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Alejandro Akrouh

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Kazuaki Miyake

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Bruce W Patterson

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Colin G Nichols

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Kenneth S Polonsky

9

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Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

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publication date

2 June 2009

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Europe PubMed Central

PMC publication ID

19 August 2017

number of pages

10

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based on heuristic

inferred from page(s)

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Europe PubMed Central

PMC publication ID

19 August 2017

58

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Europe PubMed Central

PMC publication ID

19 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1869-1878

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Association of the Kir6.2 E23K variant with reduced acute insulin response in African-Americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2712777

6 September 2017

Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism

1 reference

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6 September 2017

Genetic variations in the pancreatic ATP-sensitive potassium channel, beta-cell dysfunction, and susceptibility to type 2 diabetes

1 reference

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Nonalcoholic fatty liver disease is associated with hepatic and skeletal muscle insulin resistance in overweight adolescents

1 reference

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6 September 2017

New gene variants alter type 2 diabetes risk predominantly through reduced beta-cell function

1 reference

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program

1 reference

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Hypothalamic K(ATP) channels control hepatic glucose production

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6 September 2017

Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features

1 reference

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Current status of the E23K Kir6.2 polymorphism: implications for type-2 diabetes

1 reference

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1 reference

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6 September 2017

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

1 reference

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6 September 2017

Nucleotide sensitivity of pancreatic ATP-sensitive potassium channels and type 2 diabetes

1 reference

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6 September 2017

Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity

1 reference

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The kinetic and physical basis of K(ATP) channel gating: toward a unified molecular understanding

1 reference

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Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

1 reference

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6 September 2017

Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro

1 reference

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Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations

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Hepatic metabolism of insulin

1 reference

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Conductance fluctuations and ionic pores in membranes

1 reference

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ATP and sulfonylurea sensitivity of mutant ATP-sensitive K+ channels in neonatal diabetes: implications for pharmacogenomic therapy

1 reference

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14 September 2017

Kir6.2 polymorphisms sensitize beta-cell ATP-sensitive potassium channels to activation by acyl CoAs: a possible cellular mechanism for increased susceptibility to type 2 diabetes?

1 reference

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Binding and degradation of 125I-insulin by rat hepatocytes

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Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir6.2 and their relationships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM.

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Serum tolbutamide and chlorpropamide concentrations in patients with diabetes mellitus

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The E23K variant of KCNJ11 and the risk for severe sulfonylurea-induced hypoglycemia in patients with type 2 diabetes

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Impact of Kir6.2 E23K polymorphism on the development of type 2 diabetes in a general Japanese population: The Hisayama Study

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The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

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Clinical presentation and early course of type 1 diabetes in patients with and without thyroid autoimmunity

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inferred from PubMed ID database lookup

Identifiers

10.2337/DB09-0025

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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