(Q37275769)

19 August 2017

Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R. (English)

1 reference

19 August 2017

2

1 reference

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31 May 2020

Mohamed Bentires-Alj

9

1 reference

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31 May 2020

author name string

D S Meyer

1

1 reference

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31 May 2020

C Leroy

3

1 reference

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31 May 2020

H Brinkhaus

4

1 reference

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31 May 2020

U Müller

5

1 reference

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31 May 2020

I Klebba

6

1 reference

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31 May 2020

M Müller

7

1 reference

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31 May 2020

R D Cardiff

8

1 reference

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31 May 2020

language of work or name

1 reference

30 September 2013

1 reference

19 August 2017

1 reference

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31 May 2020

volume

2

1 reference

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31 May 2020

page(s)

e74

1 reference

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https://scigraph.springernature.com/pub.10.1038/oncsis.2013.38

31 May 2020

exact match

0 references

cites work

Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors.

1 reference

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Comprehensive molecular portraits of human breast tumours

6 September 2017

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Physiological levels of Pik3ca(H1047R) mutation in the mouse mammary gland results in ductal hyperplasia and formation of ERα-positive tumors

6 September 2017

1 reference

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Initiating breast cancer by PIK3CA mutation

6 September 2017

1 reference

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Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance (review).

6 September 2017

1 reference

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Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway-dependent and PI3K pathway-independent mechanisms

6 September 2017

1 reference

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Functional characterization of stem cell activity in the mouse mammary gland

6 September 2017

1 reference

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PIK3CA mutations in in situ and invasive breast carcinomas

6 September 2017

1 reference

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Identification of novel gene amplifications in breast cancer and coexistence of gene amplification with an activating mutation of PIK3CA

6 September 2017

1 reference

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PIK3CA mutation associates with improved outcome in breast cancer.

6 September 2017

1 reference

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PI3K pathway alterations in cancer: variations on a theme

6 September 2017

1 reference

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Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms

6 September 2017

1 reference

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AKT/PKB signaling: navigating downstream

6 September 2017

1 reference

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Cancer-specific mutations in PIK3CA are oncogenic in vivo

6 September 2017

1 reference

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Oncogenic PI3K deregulates transcription and translation

6 September 2017

1 reference

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The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells

6 September 2017

1 reference

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Somatic mutation and gain of copy number of PIK3CA in human breast cancer

6 September 2017

1 reference

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PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

6 September 2017

1 reference

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High frequency of mutations of the PIK3CA gene in human cancers

6 September 2017

1 reference

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Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells

6 September 2017

1 reference

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Targeting mammary epithelial cells using a bacterial artificial chromosome

14 September 2017

1 reference

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Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors

28 September 2017

1 reference

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Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.

26 June 2018

1 reference

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Alveolar progenitor cells develop in mouse mammary glands independent of pregnancy and lactation.

3 September 2018

1 reference

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Frequent mutation of the PIK3CA gene in ovarian and breast cancers.

3 September 2018

1 reference

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The PIK3CA gene is mutated with high frequency in human breast cancers.

3 September 2018

1 reference

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Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice

3 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FONCSIS.2013.38

Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONCSIS.2013.38

PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients

31 March 2020

1 reference

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Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression

31 March 2020

1 reference

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31 March 2020

Identifiers

DOI

10.1038/ONCSIS.2013.38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24080956%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24080956%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

24080956

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24080956%20AND%20SRC:MED&resulttype=core&format=json