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The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
scientific article published on 29 February 2016
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scholarly article
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Europe PubMed Central
PMCID
5036938
retrieved
19 August 2017
title
The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
(English)
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Europe PubMed Central
PMCID
5036938
retrieved
19 August 2017
author
Raphael Kopan
series ordinal
3
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Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
author name string
Mustafa Turkoz
series ordinal
1
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Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
R Reid Townsend
series ordinal
2
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Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
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English
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publication date
29 February 2016
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PMCID
5036938
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19 August 2017
published in
Journal of Investigative Dermatology
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stated in
Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
volume
136
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Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
issue
6
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Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
page(s)
1106-1115
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Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
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Notch signaling represses p63 expression in the developing surface ectoderm
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Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged mice
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Elevated epidermal thymic stromal lymphopoietin levels establish an antitumor environment in the skin
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Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9.
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Notch signaling and the developing hair follicle
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The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways
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Notch signaling regulates late-stage epidermal differentiation and maintains postnatal hair cycle homeostasis
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Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells
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Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin
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Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma
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The canonical Notch signaling pathway: unfolding the activation mechanism
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Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity
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ADAM proteases: ligand processing and modulation of the Notch pathway
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Epidermal Notch signalling: differentiation, cancer and adhesion
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Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1
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6 September 2017
Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes.
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PubMed Central
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6 September 2017
Canonical notch signaling functions as a commitment switch in the epidermal lineage
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6 September 2017
Notch signalling: a simple pathway becomes complex
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6 September 2017
Notch1 is essential for postnatal hair follicle development and homeostasis
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PubMed Central
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6 September 2017
Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.
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PubMed Central
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6 September 2017
Molecular principles of hair follicle induction and morphogenesis
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6 September 2017
gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis
1 reference
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PubMed Central
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6 September 2017
The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments
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PubMed Central
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6 September 2017
The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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6 September 2017
Links between signal transduction, transcription and adhesion in epithelial bud development
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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6 September 2017
The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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6 September 2017
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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6 September 2017
A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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6 September 2017
Notch signaling: cell fate control and signal integration in development
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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6 September 2017
The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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6 September 2017
Genetic mosaic analysis indicates that the bulb region of coat hair follicles contains a resident population of several active multipotent epithelial lineage progenitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
14 September 2017
The Delta intracellular domain mediates TGF-beta/Activin signaling through binding to Smads and has an important bi-directional function in the Notch-Delta signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
14 September 2017
Notch-induced proteolysis and nuclear localization of the Delta ligand
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
14 September 2017
Mutations at the P1' position of Notch1 decrease intracellular domain stability rather than cleavage by gamma-secretase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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14 September 2017
Processing of the notch ligand delta by the metalloprotease Kuzbanian
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
28 September 2017
Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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26 June 2018
Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
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26 June 2018
Programming gene expression in developing epidermis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
26 June 2018
Gene-specific targeting of the histone chaperone asf1 to mediate silencing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
3 September 2018
Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
3 September 2018
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
3 September 2018
Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5036938
retrieved
3 December 2018
Changes in keratin gene expression during terminal differentiation of the keratinocyte
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26940862
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.JID.2016.02.018
1 reference
stated in
Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
PMCID
5036938
1 reference
stated in
Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
PubMed ID
26940862
1 reference
stated in
Europe PubMed Central
PMCID
5036938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26940862%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
ResearchGate publication ID
297587807
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