(Q37285111)

English

Reactive oxygen species-independent oxidation of thioredoxin in hypoxia: inactivation of ribonucleotide reductase and redox-mediated checkpoint control

scientific article published on 15 April 2009

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scholarly article

1 reference

Europe PubMed Central

19 August 2017

Reactive oxygen species-independent oxidation of thioredoxin in hypoxia: inactivation of ribonucleotide reductase and redox-mediated checkpoint control (English)

1 reference

Europe PubMed Central

19 August 2017

0 references

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

Harish Muniyappa

1

1 reference

Europe PubMed Central

19 August 2017

Shiwei Song

2

1 reference

Europe PubMed Central

19 August 2017

Christopher K Mathews

3

1 reference

Europe PubMed Central

19 August 2017

Kumuda C Das

4

1 reference

Europe PubMed Central

19 August 2017

language of work or name

0 references

publication date

15 April 2009

1 reference

Europe PubMed Central

19 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

19 August 2017

284

1 reference

Europe PubMed Central

19 August 2017

17069-17081

1 reference

Europe PubMed Central

19 August 2017

25

1 reference

Europe PubMed Central

19 August 2017

Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2719345

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Reactive oxygen species and cellular oxygen sensing

1 reference

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1 reference

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Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

1 reference

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Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH.

1 reference

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The role of p53 in hypoxia-induced apoptosis

1 reference

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The role of ATM and ATR in the cellular response to hypoxia and re-oxygenation

1 reference

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6 September 2017

Structure, function, and mechanism of ribonucleotide reductases

1 reference

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Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites

1 reference

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Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

1 reference

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Hypoxia links ATR and p53 through replication arrest

1 reference

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Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

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Biological consequences of tumor hypoxia

1 reference

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Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

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Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.

1 reference

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c-Jun NH2-terminal kinase-mediated redox-dependent degradation of IkappaB: role of thioredoxin in NF-kappaB activation

1 reference

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6 September 2017

Redox regulation of p53 during hypoxia

1 reference

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6 September 2017

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

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Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies

1 reference

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The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture.

1 reference

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Molecular analysis of selected cell cycle regulatory proteins during aerobic and hypoxic maintenance of human ovarian carcinoma cells

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Drug resistance mediated by cellular stress response to the microenvironment of solid tumors

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6 September 2017

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

1 reference

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A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro

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6 September 2017

Site-directed mutagenesis of active site cysteines in human thioredoxin produces competitive inhibitors of human thioredoxin reductase and elimination of mitogenic properties of thioredoxin.

1 reference

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6 September 2017

Vaccinia virus induces ribonucleotide reductase in primate cells

1 reference

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6 September 2017

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Complementary DNA encoding human colon cancer manganese superoxide dismutase and the expression of its gene in human cells

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Hypoxia induces p53 accumulation in the S-phase and accumulation of hypophosphorylated retinoblastoma protein in all cell cycle phases of human melanoma cells

1 reference

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Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner

1 reference

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Endogenous thioredoxin is required for redox cycling of anthracyclines and p53-dependent apoptosis in cancer cells

1 reference

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Inhibition of mitochondrial respiration elevates oxygen concentration but leaves regulation of hypoxia-inducible factor (HIF) intact

1 reference

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

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Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

1 reference

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ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation

1 reference

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Hypoxia and drug resistance

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ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

1 reference

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DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

1 reference

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Maspin gene expression in tumor suppression induced by overexpressing manganese-containing superoxide dismutase cDNA in human breast cancer cells

1 reference

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The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease

1 reference

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The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target

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Cell cycle distribution of hypoxia and progression of hypoxic tumour cells in vivo.

1 reference

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1 reference

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Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells

1 reference

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Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport

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An ROS generator, antimycin A, inhibits the growth of HeLa cells via apoptosis.

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Structurally dependent redox property of ribonucleotide reductase subunit p53R2.

1 reference

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Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH.

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Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest

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Detection of thioredoxin in human serum and biological samples using a sensitive sandwich ELISA with digoxigenin-labeled antibody.

1 reference

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Mismatch Binding Protein-Based Mutation Detection Systems

1 reference

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Hyperoxia induces S-phase cell-cycle arrest and p21(Cip1/Waf1)-independent Cdk2 inhibition in human carcinoma T47D-H3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19369702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19369702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements

1 reference

https://pubmed.ncbi.nlm.nih.gov/19369702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin and thioredoxin reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19369702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of manganese superoxide dismutase gene expression by thioredoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19369702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of thioredoxin and thioredoxin reductase gene expression in lungs of newborn primates by oxygen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19369702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commentary on "Hypoxia, hypoxic signaling, tissue damage, and detection of reactive oxygen species (ROS)"

1 reference

https://pubmed.ncbi.nlm.nih.gov/19369702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.008557

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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