(Q37293281)

19 August 2017

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title

Physiological roles of CLC Cl(-)/H (+) exchangers in renal proximal tubules (English)

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19 August 2017

Thomas J Jentsch

3

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author name string

Vanessa Plans

series ordinal

1

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19 August 2017

Gesa Rickheit

series ordinal

2

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19 August 2017

publication date

14 October 2008

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19 August 2017

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19 August 2017

volume

458

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19 August 2017

issue

1

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19 August 2017

page(s)

23-37

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The ClC-5 chloride channel knock-out mouse - an animal model for Dent's disease.

19 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00424-008-0597-Z

Megalin knockout mice as an animal model of low molecular weight proteinuria.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00424-008-0597-Z

Megalin and cubilin: multifunctional endocytic receptors

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00424-008-0597-Z

Barttin modulates trafficking and function of ClC-K channels

21 January 2018

1 reference

12 December 2020

Inactivation of muscle chloride channel by transposon insertion in myotonic mice

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12 December 2020

Kidney-specific upregulation of vitamin D3 target genes in ClC-5 KO mice.

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12 December 2020

Glomerular protein sieving and implications for renal failure in Fanconi syndrome

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12 December 2020

The ClC-0 chloride channel is a 'broken' Cl-/H+ antiporter

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12 December 2020

Parathyroid hormone regulates 25-hydroxyvitamin D(3)-24-hydroxylase mRNA by altering its stability

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12 December 2020

Tissue distribution and subcellular localization of the ClC-5 chloride channel in rat intestinal cells

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12 December 2020

Thyroid hormone modulates ClC-2 chloride channel gene expression in rat renal proximal tubules

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12 December 2020

Additional disruption of the ClC-2 Cl(-) channel does not exacerbate the cystic fibrosis phenotype of cystic fibrosis transmembrane conductance regulator mouse models

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12 December 2020

ATP depletion inhibits the endocytosis of ClC-2.

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12 December 2020

A common molecular basis for three inherited kidney stone diseases

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12 December 2020

Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III

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12 December 2020

Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man

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12 December 2020

An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3

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12 December 2020

Functional and structural conservation of CBS domains from CLC chloride channels.

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12 December 2020

Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels

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12 December 2020

Identification of novel human WW domain-containing proteins by cloning of ligand targets

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12 December 2020

The Chloride Channel ClC-4 Contributes to Endosomal Acidification and Trafficking

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12 December 2020

Biophysical properties of ClC-3 differentiate it from swelling-activated chloride channels in Chinese hamster ovary-K1 cells

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12 December 2020

The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover

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12 December 2020

Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes

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12 December 2020

A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction

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12 December 2020

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins

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12 December 2020

Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.

1 reference

12 December 2020

Megalin antagonizes activation of the parathyroid hormone receptor.

1 reference

12 December 2020

Nucleotide recognition by the cytoplasmic domain of the human chloride transporter ClC-5

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12 December 2020

Proximal tubular handling of phosphate: A molecular perspective

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12 December 2020

Endosomal alkalinization reduces Jmax and Km of albumin receptor-mediated endocytosis in OK cells

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12 December 2020

Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules

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12 December 2020

Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption

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12 December 2020

Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney

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12 December 2020

Crystal structure of the cytoplasmic domain of the chloride channel ClC-0.

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12 December 2020

Two highly homologous members of the ClC chloride channel family in both rat and human kidney

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12 December 2020

Gating the selectivity filter in ClC chloride channels

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12 December 2020

Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel

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12 December 2020

The cytoplasmic domain of the chloride channel ClC-0: structural and dynamic characterization of flexible regions

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12 December 2020

Functional evaluation of Dent's disease-causing mutations: implications for ClC-5 channel trafficking and internalization.

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12 December 2020

Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomes

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12 December 2020

Mutations in CLCN5 chloride channel in Japanese patients with low molecular weight proteinuria

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12 December 2020

CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis

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12 December 2020

Cellular and subcellular immunolocalization of ClC-5 channel in mouse kidney: colocalization with H+-ATPase

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12 December 2020

Heteromultimeric CLC chloride channels with novel properties

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12 December 2020

Dent's disease; a familial proximal renal tubular syndrome with low-molecular-weight proteinuria, hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance.

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12 December 2020

Localization and induction by dehydration of ClC-K chloride channels in the rat kidney.

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12 December 2020

Evidence for genetic heterogeneity in Dent's disease

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12 December 2020

Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers

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12 December 2020

CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology

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12 December 2020

Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

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12 December 2020

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

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12 December 2020

Dent Disease with mutations in OCRL1

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12 December 2020

Pores Formed by Single Subunits in Mixed Dimers of Different CLC Chloride Channels

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12 December 2020

Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney.

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12 December 2020

Localization and functional characterization of rat kidney-specific chloride channel, ClC-K1

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12 December 2020

The structure of the cytoplasmic domain of the chloride channel ClC-Ka reveals a conserved interaction interface

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12 December 2020

Estrogen modulates ClC-2 chloride channel gene expression in rat kidney.

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12 December 2020

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.

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12 December 2020

The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells

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12 December 2020

Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling

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12 December 2020

Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels

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12 December 2020

Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone, calcitonin, and 1alpha,25(OH)2D3 in intact animals

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12 December 2020

Endocytosis and molecular sorting

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12 December 2020

Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice

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12 December 2020

A chloride channel widely expressed in epithelial and non-epithelial cells

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12 December 2020

ClC-5: role in endocytosis in the proximal tubule.

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12 December 2020

Loss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout mice

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12 December 2020

The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles

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12 December 2020

Absence of ClC5 in knockout mice leads to glycosuria, impaired renal glucose handling and low proximal tubule GLUT2 protein expression.

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12 December 2020

Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus

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12 December 2020

V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway

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12 December 2020

Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.

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12 December 2020

Vacuolar ATPase activity is required for endosomal carrier vesicle formation

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12 December 2020

Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease

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12 December 2020

Posttranscriptional regulation of the proximal tubule NaPi-II transporter in response to PTH and dietary P(i).

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12 December 2020

Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease

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12 December 2020

Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders.

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12 December 2020

Altered GABAergic function accompanies hippocampal degeneration in mice lacking ClC-3 voltage-gated chloride channels

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12 December 2020

ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells

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12 December 2020

Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration

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12 December 2020

X-linked hypercalciuric nephrolithiasis: clinical syndromes and chloride channel mutations

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12 December 2020

Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines.

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12 December 2020

Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl- channel gene.

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12 December 2020

Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients

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12 December 2020

Cystic fibrosis is associated with a defect in apical receptor-mediated endocytosis in mouse and human kidney

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12 December 2020

Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion

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12 December 2020

Modeling study of human renal chloride channel (hCLC-5) mutations suggests a structural-functional relationship.

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12 December 2020

Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents.

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12 December 2020

Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells

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12 December 2020

Homodimeric architecture of a ClC-type chloride ion channel

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12 December 2020

An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease.

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12 December 2020

Dimeric structure of single chloride channels from Torpedo electroplax

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12 December 2020

Determinants of anion-proton coupling in mammalian endosomal CLC proteins

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12 December 2020

The muscle chloride channel ClC-1 is not directly regulated by intracellular ATP

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12 December 2020

Impaired acidification in early endosomes of ClC-5 deficient proximal tubule

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12 December 2020

Regulation of albumin endocytosis by PSD95/Dlg/ZO-1 (PDZ) scaffolds. Interaction of Na+-H+ exchange regulatory factor-2 with ClC-5.

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12 December 2020

ClC-3 chloride channels facilitate endosomal acidification and chloride accumulation

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12 December 2020

Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6.

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12 December 2020

Determinants of slow gating in ClC-0, the voltage-gated chloride channel of Torpedo marmorata.

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12 December 2020

Anion permeation in human ClC-4 channels

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12 December 2020

Two physically distinct pores in the dimeric ClC-0 chloride channel.

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12 December 2020

Golgi localization and functionally important domains in the NH2 and COOH terminus of the yeast CLC putative chloride channel Gef1p

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12 December 2020

Leukoencephalopathy upon disruption of the chloride channel ClC-2.

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12 December 2020

The skeletal muscle chloride channel in dominant and recessive human myotonia

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12 December 2020

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome

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12 December 2020

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells

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12 December 2020

ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease.

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12 December 2020

Open-state substructure of single chloride channels from Torpedo electroplax

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12 December 2020

Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure

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12 December 2020

Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion.

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12 December 2020

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.

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12 December 2020

Dent disease-like phenotype and the chloride channel ClC-4 (CLCN4) gene.

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12 December 2020

ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function

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12 December 2020

Completely functional double-barreled chloride channel expressed from a single Torpedo cDNA

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12 December 2020

Separate ion pathways in a Cl-/H+ exchanger

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12 December 2020

Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter

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12 December 2020

Nucleotides bind to the C-terminus of ClC-5.

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12 December 2020

Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dent's disease (an X-linked hereditary nephrolithiasis).

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12 December 2020

X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity

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12 December 2020

10.1007/S00424-008-0597-Z

Identifiers

DOI

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19 August 2017

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