(Q37295725)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19538468%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Anti-proliferative effect of rhein, an anthraquinone isolated from Cassia species, on Caco-2 human adenocarcinoma cells (English)

1 reference

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31 January 2020

1 reference

1 reference

Angela Maria Acquaviva

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19538468%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Mark McCann

6

1 reference

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31 January 2020

Angelo A. Izzo

8

1 reference

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31 January 2020

author name string

Gabriella Aviello

1

1 reference

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31 January 2020

Ian Rowland

2

1 reference

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31 January 2020

Christopher I Gill

3

1 reference

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31 January 2020

Francesco Capasso

5

1 reference

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31 January 2020

Raffaele Capasso

7

1 reference

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31 January 2020

Francesca Borrelli

9

1 reference

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31 January 2020

publication date

16 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19538468%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular and Molecular Medicine

31 January 2020

published in

1 reference

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31 January 2020

volume

14

1 reference

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31 January 2020

issue

7

1 reference

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31 January 2020

page(s)

2006-2014

1 reference

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Neutral red uptake assay for the estimation of cell viability/cytotoxicity

31 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Reactive oxygen species and antioxidant mechanisms in human tissues and their relation to malignancies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

ERK implication in cell cycle regulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Pathophysiology, diagnosis and current management of chronic constipation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Myths and misconceptions about chronic constipation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Evaluation of the Caco-2 monolayer as a model epithelium for iontophoretic transport

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Laxative use not a risk for colorectal cancer: data from the Melbourne Colorectal Cancer Study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Anthranoid laxative abuse--a risk for colorectal cancer?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Anthraquinone laxatives and human cancer: an association in one case

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Constipation, laxative use, and colon cancer in a North Carolina population

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Antioxidant effectiveness of phenolic apple juice extracts and their gut fermentation products in the human colon carcinoma cell line caco-2.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Studies on the chemical constituents and anticancer activity of Saxifraga stolonifera (L) Meeb

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Isolation and inhibitory activity against ERK phosphorylation of hydroxyanthraquinones from rhubarb.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Effects of fermentation products of pro- and prebiotics on trans-epithelial electrical resistance in an in vitro model of the colon.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Comparative analysis of EspF from enteropathogenic and enterohemorrhagic Escherichia coli in alteration of epithelial barrier function

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Inhibition of human tumor cell proliferation by novel anthraquinones from daylilies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Laxatives and intestinal epithelial cells: a morphological study of epithelial cell damage and proliferation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Cancer risk and oxidative DNA damage in man.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

The effect of an anthraquinone laxative on colonic nerve tissue: a controlled trial in constipated women

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Alterations in colonic anatomy induced by chronic stimulant laxatives: the cathartic colon revisited

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Retrospective study on laxative use and melanosis coli as risk factors for colorectal neoplasma.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Melanosis coli: Studies of the toxic effects of irritant purgatives

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Response of cell cycle/stress-related protein expression and DNA damage upon treatment of CaCo2 cells with anthocyanins

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Fermentation of resistant starches: influence of in vitro models on colon carcinogenesis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Is pseudomelanosis coli a marker of colonic neuropathy in severely constipated patients?

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Effects of uptake of flavonoids on oxidative stress induced by hydrogen peroxide in human intestinal Caco-2 cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Senna and the formation of aberrant crypt foci and tumors in rats treated with azoxymethane

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Potential anti-cancer effects of virgin olive oil phenols on colorectal carcinogenesis models in vitro.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Antigenotoxic properties of Cassia tea (Cassia tora L.): mechanism of action and the influence of roasting process

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayers

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Constipation, anthranoid laxatives, melanosis coli, and colon cancer: a risk assessment using aberrant crypt foci.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Does senna extract promote growth of aberrant crypt foci and malignant tumors in rat colon?

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Nuclear aberrations as a short-term test for genotoxicity to the colon: evaluation of nineteen agents in mice.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Effects of ‘Contact Laxatives’ on Intestinal and Colonic Epithelial Cell Proliferation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3823282

Involvement of prostaglandin E-like material in the purgative action of rhein anthrone, the intraluminal active metabolite of sennosides A and B in mice

3 December 2018

1 reference

12 December 2020

Dual effect of orally administered sennosides on large intestine transit and fluid absorption in the rat

1 reference

12 December 2020

Metabolism of sennosides and rhein in the rat

1 reference

12 December 2020

Site-specific induction of nuclear anomalies (apoptotic bodies and micronuclei) by carcinogens in mice

1 reference

12 December 2020

Ultrastructural modifications of intercellular junctions between tumor cells

1 reference

12 December 2020

Apoptosis induction by sennoside laxatives in man; escape from a protective mechanism during chronic sennoside use?

1 reference

12 December 2020

Effect of anthraquinone-laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells

1 reference

12 December 2020

Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2)

1 reference

12 December 2020

Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal

1 reference

12 December 2020

Excessively high cell proliferation in sigmoid colon after an oral purge with anthraquinone glycosides

1 reference

12 December 2020

Influence of a highly purified senna extract on colonic epithelium

1 reference

12 December 2020

10.1111/J.1582-4934.2009.00815.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19538468%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19538468%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

19538468

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19538468%20AND%20SRC:MED&resulttype=core&format=json