(Q37306454)

19 August 2017

3 references

24 August 2020

18 July 2021

Anti-carcinogenic effects of the flavonoid luteolin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

1 reference

ChEBI release 2020-05-28

1 reference

24 August 2020

cell population proliferation

1 reference

18 July 2021

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

2

Irmgard Merfort

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

author name string

Günter Seelinger

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

Christoph M Schempp

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

22 October 2008

3 references

19 August 2017

24 August 2020

18 July 2021

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

24 August 2020

18 July 2021

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

page(s)

2628-2651

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

Creative Commons Attribution

12 May 2020

copyright license

2 references

24 August 2020

18 July 2021

0 references

Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

The chemistry behind antioxidant capacity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Phenolics as potential antioxidant therapeutic agents: mechanism and actions

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Structural dependence of flavonoid interactions with Cu2+ ions: implications for their antioxidant properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Regioselectivity of phase II metabolism of luteolin and quercetin by UDP-glucuronosyl transferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Glucuronidase deconjugation in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Cancer preventive mechanisms of the green tea polyphenol (-)-epigallocatechin-3-gallate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Antiproliferative activity of flavonoids on several cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Chemopreventive effects of minor dietary constituents in common foods on human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Caspase activation and extracellular signal-regulated kinase/Akt inhibition were involved in luteolin-induced apoptosis in Lewis lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Luteolin induced DNA damage leading to human lung squamous carcinoma CH27 cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Antioxidant enzymes activity involvement in luteolin-induced human lung squamous carcinoma CH27 cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21(WAF1/CIP1) expression with rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Downregulation of androgen receptor expression by luteolin causes inhibition of cell proliferation and induction of apoptosis in human prostate cancer cells and xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Tumor infiltrating macrophages reduce development of peritoneal colorectal carcinoma metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Inhibitory effect of Perilla leaf extract and luteolin on mouse skin tumor promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Protective effect of quercetin and luteolin in human melanoma HMB-2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Modulation of interleukin-1beta mediated inflammatory response in human astrocytes by flavonoids: implications in neuroprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Antimutagenic effect of plant flavonoids in the Salmonella assay system

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

The effect of paclitaxel on gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Topoisomerase II inhibition and high yield of endoreduplication induced by the flavonoids luteolin and quercetin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Luteolin sensitizes the anticancer effect of cisplatin via c-Jun NH2-terminal kinase-mediated p53 phosphorylation and stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Down-regulation of prostate specific antigen in LNCaP cells by flavonoids from the pollen of Brassica napus L.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Induction of apoptosis by luteolin through cleavage of Bcl-2 family in human leukemia HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Induction apoptosis of luteolin in human hepatoma HepG2 cells involving mitochondria translocation of Bax/Bak and activation of JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Pro-apoptotic effects of the flavonoid luteolin in rat H4IIE cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Flavonoids and breast cancer risk in Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Flavonoid intake and breast cancer risk: a case--control study in Greece

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Fruits, vegetables, and micronutrient intake in relation to breast cancer survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Flavonoids and colorectal cancer in Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Flavonoids and the risk of renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Dietary flavonoids and cancer risk: evidence from human population studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES13102628

Protective role of luteolin in 1,2-dimethylhydrazine induced experimental colon carcinogenesis

21 January 2018

1 reference

12 December 2020

The free radical scavenging activity of four flavonoids determined by the comet assay.

1 reference

12 December 2020

In vivo skin penetration studies of camomile flavones

1 reference

12 December 2020

Cytotoxic flavonoids from Vitex agnus-castus

1 reference

12 December 2020

Flavonoids suppress androgen-independent human prostate tumor proliferation

1 reference

12 December 2020

[Comparison of antioxidative and antitumor activities of six flavonoids from Epimedium koreanum]

1 reference

12 December 2020

Flavonoids activate wild-type p53.

1 reference

12 December 2020

Dietary flavonoid intake and breast cancer survival among women on Long Island

1 reference

12 December 2020

Anti-tumor promoting potential of luteolin against 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats

1 reference

12 December 2020

Inhibition by quercetin and luteolin of chromosomal alterations induced by salted, deep-fried fish and mutton in rats

1 reference

12 December 2020

Effects of luteolin on arylamine N-acetyltransferase activity in human liver tumour cells.

1 reference

12 December 2020

Antineoplastic agents 338. The cancer cell growth inhibitory. Constituents of Terminalia arjuna (Combretaceae).

1 reference

12 December 2020

Radioprotective effect of antioxidative flavonoids in gamma-ray irradiated mice

1 reference

12 December 2020

Bioflavonoids, type II [H-3]estradiol binding sites and prostatic cancer cell proliferation

1 reference

12 December 2020

Inhibitory effect of Perilla frutescens and its phenolic constituents on cultured murine mesangial cell proliferation

1 reference

12 December 2020

Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes

1 reference

12 December 2020

Genotoxicity of quercetin in cultured mammalian cells

1 reference

12 December 2020

A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer

1 reference

12 December 2020

Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis.

1 reference

12 December 2020

[Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60]

1 reference

12 December 2020

Structure-activity relationships of flavonoids and the induction of granulocytic- or monocytic-differentiation in HL60 human myeloid leukemia cells

1 reference

12 December 2020

Distinct mechanisms of DNA damage in apoptosis induced by quercetin and luteolin

1 reference

12 December 2020

[Effect of three flavones on enzyme activity of recombinant human phosphoinositide 3-kinase p110beta catalytic subunit]

1 reference

12 December 2020

Chemopreventive potential of luteolin during colon carcinogenesis induced by 1,2-dimethylhydrazine.

1 reference

12 December 2020

Pharmacokinetics and bioavailability of the flavonol quercetin in humans.

1 reference

12 December 2020

Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells

1 reference

12 December 2020

Luteolin induces N-acetylation and DNA adduct of 2-aminofluorene accompanying N-acetyltransferase activity and gene expression in human bladder cancer T24 cell line

1 reference

12 December 2020

Functional diversity of flavonoids in the inhibition of the proinflammatory NF-kappaB, IRF, and Akt signaling pathways in murine intestinal epithelial cells.

1 reference

12 December 2020

[Current understanding of the metabolism of flavonoids. II. Adsorption and metabolism of flavones, flavonones, flavanes, proanthocyanidens and isoflavonoids]

1 reference

12 December 2020

Growth inhibitory effects of bioflavonoids and related compounds on human leukemic CEM-C1 and CEM-C7 cells

1 reference

12 December 2020

Determination of free radical scavenging activity of quercetin, rutin, luteolin and apigenin in H2O2-treated human ML cells K562.

1 reference

12 December 2020

10.3390/MOLECULES13102628

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6245397&resulttype=core&format=json

12 May 2020

1 reference