(Q37307236)

19 August 2017

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title

Relevance of transgenic mouse models to human Alzheimer disease (English)

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19 August 2017

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Debbi A Morrissette

1

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19 August 2017

Anna Parachikova

series ordinal

2

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19 August 2017

Kim N Green

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3

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19 August 2017

Frank M LaFerla

series ordinal

4

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19 August 2017

language of work or name

English

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publication date

22 October 2008

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Journal of Biological Chemistry

19 August 2017

5

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based on heuristic

inferred from page(s)

published in

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19 August 2017

284

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19 August 2017

10

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19 August 2017

6033-6037

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The gamma-secretase complex: membrane-embedded proteolytic ensemble

19 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Intracellular amyloid-beta in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Tau pathology in Alzheimer disease and other tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

The significance of neuroinflammation in understanding Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Linking calcium to Abeta and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Inflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Has the amyloid cascade hypothesis for Alzheimer's disease been proved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

The role of amyloid beta peptide 42 in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Extracellular amyloid formation and associated pathology in neural grafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Comparative analysis of amyloid-beta chemical structure and amyloid plaque morphology of transgenic mouse and Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Plaques, tangles, and memory loss in mouse models of neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

A beta oligomers - a decade of discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Soluble Abeta oligomers ultrastructurally localize to cell processes and might be related to synaptic dysfunction in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

A decade of tau transgenic animal models and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Pathways by which Abeta facilitates tau pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

The ubiquitin-proteasome system in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

The mouse C1q A-chain sequence alters beta-amyloid-induced complement activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

The molecular basis of the prevention of Alzheimer's disease through healthy nutrition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Inflammation in neurodegenerative disease--a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Regulation of NMDA receptor trafficking by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Calcium-regulated signaling pathways: role in amyloid beta-induced synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Alzheimer's disease is a synaptic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

APP processing and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Altered synaptic function in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

Genetic background regulates -amyloid precursor protein processing and -amyloid deposition in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R800030200

21 January 2018

Identifiers

DOI

10.1074/JBC.R800030200

1 reference

19 August 2017

1 reference